Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,150

Sort By: Relevance

$110K - $150K *

Advance cloud infrastructure by designing, deploying, and managing scalable solutions. Collaborate with teams to ensure compliance, optimize costs, and enhance operational efficiency while supporting...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$170K - $200K *

Empower a high-growth organization by leading operations strategy, enhancing client satisfaction, and driving efficiency through AI and automation. Collaborate with senior leadership to ensure financi...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$170K - $250K *

Unlock potential by owning a product area end-to-end, collaborating with engineering and customers to drive innovation and deliver impactful solutions in a dynamic market...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Staffing

$76K - $95K *

Advance the intake process by managing conflicts analysis, ensuring timely responses, and supporting new client matters. Collaborate with attorneys and staff to uphold high service standards across mu...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$95K - $115K *

Analyze financial performance and operational metrics to support strategic growth initiatives. Collaborate with cross-functional teams to enhance reporting accuracy and drive insights for decision-mak...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to creating impactful medical education content for healthcare providers and patients. Collaborate closely with scientific and account teams to deliver high-quality materi...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Join a team that's transforming home and specialty insurance solutions through data-driven analysis and innovative project management, delivering value to customers and driving growth in a dynamic env...

RemoteRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Drive growth by managing key national accounts, optimizing revenue, and enhancing client satisfaction through strategic relationship building and collaboration across teams...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$73K - $102K *

Drive end-to-end Oracle EBS R12 upgrades, ensuring seamless technical design, configuration, and deployment. Collaborate with teams to resolve issues, develop customizations, and enhance system integr...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$173K - $255K *

Join a dynamic team to enhance product security throughout the development lifecycle. Collaborate with engineering and product teams to identify vulnerabilities, automate processes, and implement secu...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Transform the future of data center construction by leading mechanical field delivery. Oversee contractors and ensure safe installation of cooling infrastructure, while coordinating with multiple team...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Take ownership of client relationships and campaign performance, managing a portfolio of accounts. Lead strategy discussions, optimize Meta campaigns, and ensure client satisfaction through proactive...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$118K - $222K *

Empower the delivery of transformative technology initiatives by collaborating with leaders to enhance project execution, manage dependencies, and drive value across teams, ensuring successful outcome...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$75K - $90K *

Champion client success by managing media dashboard projects and audience creation across multiple accounts. Collaborate with teams to ensure accurate tracking and actionable insights, driving perform...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Media

$100K - $130K *

Transform healthcare by leading a dynamic PMO, ensuring program transparency and compliance across multiple customer accounts while fostering collaboration and continuous improvement...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $90K *

Unlock new business opportunities by developing strategic marketing and sales plans. Collaborate with executives to secure and grow employer accounts, driving revenue growth and expanding market share...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Join a team that's transforming healthcare by driving enterprise sales and partnerships with leading health systems. Leverage your expertise to educate executives on innovative solutions that enhance...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $100K *

Develop strategic customer relationships and expand international presence by acquiring new enterprise clients and nurturing existing accounts in the pharmaceutical and life sciences sectors...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $120K *

Explore innovative marketing automation solutions by collaborating with teams to implement Salesforce Marketing Cloud technologies, ensuring high-quality execution and strategic alignment for client c...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$165K - $185K *

Unlock your potential by leading the design and implementation of innovative digital solutions for Veteran healthcare services. Collaborate with cross-functional teams to enhance enterprise applicatio...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$166K - $200K *

Engage with strategic accounts to drive sales growth and build influential relationships. Leverage deep industry knowledge to create tailored solutions, manage complex negotiations, and achieve perfor...

RemoteRemote

2 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$150K - $185K *

Shape the future of oncology solutions by leading product strategy and execution for a groundbreaking genomic profiling product line, driving innovation and enhancing patient care through cross-functi...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$330K - $375K *

Elevate your career by joining a dedicated team of Psychiatrists focused on patient care and clinical excellence, offering flexible schedules and a supportive environment for both full-time and part-t...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Elevate project outcomes by leading cross-functional teams to deliver clinical research projects on time and within budget, ensuring compliance with regulatory standards and client expectations while...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$104K - $130K *

Empower growth by transforming complex data into actionable insights. Collaborate with senior leaders to build analytical tools and models that drive strategic decisions, while enhancing operational e...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.