Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,130

Sort By: Relevance

$110K - $130K *

Optimize clinical trial operations by leading cross-functional teams, managing vendor relationships, and ensuring compliance with regulatory standards to drive successful study execution and patient e...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$129K - $231K *

Elevate nonclinical toxicology operations by managing study execution, ensuring compliance, and fostering collaboration across teams to advance innovative therapies for sleep-wake disorders. Drive acc...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Build strong relationships and drive sales for advanced wound care products in a defined territory. Achieve revenue targets through strategic planning, customer engagement, and exceptional service in...

RemoteRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Partner with us to drive customer success by implementing and expanding Teleport solutions. Leverage your expertise to enhance adoption, troubleshoot issues, and deliver tailored training, ensuring cl...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Elevate revenue growth by driving sales of innovative traffic management solutions to government agencies. Collaborate with partners, identify opportunities, and build strong relationships to achieve...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Transportation

$84K - $131K *

Engineer innovative web applications by leveraging Java and Spring Boot. Collaborate across teams to implement DevSecOps practices, ensuring secure, efficient delivery while integrating AI capabilitie...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$320K - $488K *

Join a team that's pushing the boundaries of innovation in rack-scale system software. Lead technical design efforts, collaborate with top industry players, and drive quality across a rapidly evolving...

United StatesRemote

Reposted 2 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$100K - $110K *

Empower corporate veterinary groups by driving software adoption and growth. Collaborate with cross-functional teams to develop strategic partnerships, influence decisions, and enhance customer satisf...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Collaborate with us to develop and configure Guidewire PolicyCenter solutions, enhancing the policy lifecycle for Personal and Commercial Lines of Business while integrating advanced technologies and...

2 days ago

  •   5 - 7 years exp.  •   Staffing

$95K - $115K *

Elevate the future of advanced compute platforms by leading test engineering in a high-volume manufacturing environment. Drive product quality and operational excellence through innovative troubleshoo...

2 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$95K - $115K *

Join a team that's driving innovation in next-gen compute platforms. Lead test engineering in a high-volume environment, enhancing product quality and performance through advanced troubleshooting, aut...

2 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$110K - $130K *

Join a team that's dedicated to fostering strategic relationships with enterprise customers, ensuring successful adoption and optimization of technology solutions in the financial services sector whil...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$105K - $150K *

Join a team that's transforming construction project management through technology. Leverage your industry expertise to guide customers in adopting Autodesk solutions, enhancing workflows, and driving...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Join a dynamic team to architect and implement cutting-edge MLOps strategies, leveraging Google Cloud's AI/ML stack. Drive innovation in model lifecycle management and collaborate with cross-functiona...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $115K *

Lead the charge in enhancing customer support by guiding a skilled team of Support Engineers. Balance hands-on technical assistance with operational oversight to ensure a world-class experience for cl...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $170K *

Lead the charge in modernizing enterprise security by investigating and mitigating critical vulnerabilities. Collaborate across teams to drive risk reduction and enhance operational effectiveness in a...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$105K - $140K *

Champion clinical trial excellence by leading a high-performing CRA team, ensuring compliance with ICH-GCP and local regulations while fostering a positive team culture and optimizing site relationshi...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K *

Join a team that's driving impactful cross-functional initiatives by leading strategic delivery efforts. Leverage your project management expertise to align complex projects with enterprise priorities...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Drive regional sales growth by developing strategies, managing key accounts, and expanding market presence. Engage with K-12 leaders to enhance customer relationships and achieve sales targets while m...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$83K - $138K *

Lead the strategy and performance management for our mobile app and loyalty experience, driving athlete engagement and revenue growth through cross-functional collaboration and data-driven insights. O...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$112K - $132K *

Join a team that's shaping the future of autism care by building robust statistical methodologies. You'll analyze real-world clinical data, ensuring rigorous evaluation of outcomes and social validity...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Champion the growth of strategic travel partnerships by leading enterprise sales efforts, securing high-value accounts, and leveraging modern sales frameworks to drive commercial success in a fast-pac...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$185K - $265K *

Engage in strategic leadership to design and implement partner programs that drive pipeline growth, enhance partner enablement, and ensure operational excellence across cross-functional teams for scal...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$85K - $110K *

Unlock potential by leading end-to-end payroll processing across multiple US entities, ensuring compliance and accuracy while contributing to the evolution of a global payroll model within a dynamic...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$180K - $220K *

Drive high-value sales and elevate team performance by mentoring Account Executives. Leverage your expertise in complex negotiations while managing a strategic pipeline to achieve personal and team su...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.