Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$100K - $110K *

Empower decision-making by developing impactful Power BI dashboards and reports. Collaborate with data engineers and stakeholders to create semantic models and ensure data quality, enhancing analytics...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$249K - $338K *

Architect innovative embedded software solutions, leading design, development, and integration efforts. Collaborate with cross-functional teams to ensure compliance with industry standards while enhan...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$57K - $108K *

Invent the future of defense systems as a Systems Engineer I, collaborating with cross-functional teams to develop cutting-edge Open System Architecture products. Contribute to requirements developmen...

2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$150K - $180K *

Transform patient access services by leading a diverse team, managing client portfolios, and driving operational excellence to exceed performance targets while fostering strong client relationships an...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Healthcare

$91K - $143K *

Unlock potential by providing high-level administrative support to senior executives, managing complex schedules, facilitating communication, and ensuring seamless operations in a dynamic environment...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$139K - $190K *

Accelerate progress at the intersection of technology and safety by leading cross-functional initiatives to combat fraud and abuse. Collaborate with diverse teams to implement effective defenses and e...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$143K - $194K *

Elevate your career by leading strategic media initiatives for Medical Affairs, translating scientific priorities into impactful media strategies, and optimizing campaigns to enhance communication and...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$83K - $133K *

Drive sales growth by building strong customer relationships and delivering tailored solutions in the Force Measurement sector. Collaborate with teams to identify market opportunities and enhance cust...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead the charge in delivering impactful customer experience consulting by analyzing complex data, mentoring junior consultants, and driving projects to successful, measurable results, all while ensuri...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $110K *

Lead the enablement program for customer-facing teams, ensuring they are equipped with the latest product knowledge and skills. Collaborate with Sales and CS leaders to create impactful training sessi...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$166K - $187K *

Empower patients by delivering high-quality, evidence-based primary care through innovative digital platforms. Collaborate with a diverse team to manage complex health needs and enhance patient outcom...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Provide comprehensive clinical care for individuals with substance use disorders, focusing on assessment, diagnosis, and treatment. Collaborate with interdisciplinary teams to ensure effective medicat...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Drive the evolution of a comprehensive Product Security program, overseeing security integration across multiple product offerings. Collaborate with teams to enhance security practices while ensuring...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $185K *

Pioneer growth marketing strategies as you drive customer acquisition, optimize funnels, and elevate conversion rates. Collaborate across functions to maximize impact and harness data-driven decisions...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$170K - $325K *

Lead the development of control-plane architecture for AI inference systems. Collaborate across hardware and software to create robust, secure, and scalable solutions, ensuring seamless integration an...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$78K - $107K *

Contribute to impactful healthcare analytics by designing and executing rigorous outcomes studies. Collaborate with multidisciplinary teams to translate complex data into actionable insights that enha...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $130K *

Join our team to drive sales growth by cultivating leads and executing sales strategies for innovative SaaS solutions, enhancing learning and development across enterprise organizations...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Join a dynamic team to lead proposal and security response efforts, driving innovation and quality. Manage a skilled group, streamline processes, and enhance collaboration across functions to achieve...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$166K - $198K *

Elevate your career by driving talent acquisition for high-impact engineering teams. Collaborate with hiring managers to refine processes and build strong candidate pipelines, ensuring a seamless expe...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Business Services

$75K - $125K *

Advance your career in technology sales by building relationships and driving growth in the SLED market. Collaborate with top tech brands and leverage support to achieve your sales goals while develop...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Advance your career by owning the full sales cycle for multi-location auto repair groups. Drive pipeline growth through outbound efforts and strategic partnerships, while aligning stakeholders on impa...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Optimize client compensation strategies by managing complex projects, delivering advanced expertise, and mentoring team members. Drive measurable outcomes through data-driven insights and strategic re...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Business Services

$150K - $190K *

Take ownership of actuarial modeling efforts, oversee team activities, and innovate integration of new product regulatory requirements in a collaborative environment focused on professional growth...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Staffing

$120K - $145K *

Elevate the AI sales platform by transforming seller challenges into innovative solutions. Collaborate with cross-functional teams to enhance product capabilities, drive user adoption, and shape the r...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Media

$175K - $210K *

Lead the execution of energy infrastructure investments, managing complex programs from development to delivery. Drive governance, cross-functional coordination, and external partnerships to ensure ti...

RemoteRemote

2 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.