Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$90K - $115K *

Optimize contract processes by collaborating with Sales, Legal, and Finance to ensure compliance and efficiency. Drive operational excellence and risk management while supporting timely contract execu...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Architect and manage complex SAP environments, ensuring optimal performance and security. Lead installations, upgrades, and migrations while collaborating with stakeholders to deliver tailored solutio...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$223K - $293K *

Transform the future of R&D by leading digital product strategy and execution, enhancing study budget management and resource forecasting through innovative technology solutions and cross-functional c...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape enterprise sales strategies by driving growth in large home-care organizations. Own the full sales cycle, engage with C-suite executives, and advocate for innovative solutions in a dynamic healt...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $121K *

Empower global supply chain efficiency by overseeing hardware supply planning. Collaborate with cross-functional teams to develop production and capacity plans, ensuring optimal inventory levels while...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$118K - $222K *

Lead the charge in managing cross-functional workstreams to deliver impactful technology solutions. Collaborate with stakeholders to drive business outcomes, mitigate risks, and enhance delivery pract...

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$140K - $160K *

Elevate your career by driving impactful client reporting and analytics. Collaborate with cross-functional teams to deliver actionable insights that enhance client outcomes and support business growth...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$163K - $226K *

Join a team that's dedicated to enhancing product security and privacy. Collaborate with technical experts to identify vulnerabilities, implement solutions, and promote secure coding practices while w...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$113K - $217K *

Shape the future of competitive strategy by transforming insights into actionable sales tactics. Collaborate with cross-functional teams to enhance market positioning, drive revenue growth, and improv...

RemoteRemote

2 days ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$151K - $199K *

Empower sales teams by designing and delivering innovative training programs that enhance product knowledge and sales techniques, ensuring alignment with marketing strategies and industry trends to dr...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$145K - $168K *

Shape the future of the Food & Beverage market by driving growth, building strategic relationships, and leveraging technical expertise to enhance market presence and customer satisfaction across diver...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Drive profitable growth through strategic paid social media management, overseeing campaigns on Meta and TikTok. Collaborate with creative teams and analysts to optimize performance, scale budgets, an...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$85K *

Shape transformative educational environments by collaborating with clients to design tailored solutions that enhance learning experiences and drive measurable outcomes in schools...

2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $110K *

Empower decision-making by developing impactful Power BI dashboards and reports. Collaborate with data engineers and stakeholders to create semantic models and ensure data quality, enhancing analytics...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$249K - $338K *

Architect innovative embedded software solutions, leading design, development, and integration efforts. Collaborate with cross-functional teams to ensure compliance with industry standards while enhan...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$57K - $108K *

Invent the future of defense systems as a Systems Engineer I, collaborating with cross-functional teams to develop cutting-edge Open System Architecture products. Contribute to requirements developmen...

2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$150K - $180K *

Transform patient access services by leading a diverse team, managing client portfolios, and driving operational excellence to exceed performance targets while fostering strong client relationships an...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Healthcare

$91K - $143K *

Unlock potential by providing high-level administrative support to senior executives, managing complex schedules, facilitating communication, and ensuring seamless operations in a dynamic environment...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$139K - $190K *

Accelerate progress at the intersection of technology and safety by leading cross-functional initiatives to combat fraud and abuse. Collaborate with diverse teams to implement effective defenses and e...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$143K - $194K *

Elevate your career by leading strategic media initiatives for Medical Affairs, translating scientific priorities into impactful media strategies, and optimizing campaigns to enhance communication and...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$83K - $133K *

Drive sales growth by building strong customer relationships and delivering tailored solutions in the Force Measurement sector. Collaborate with teams to identify market opportunities and enhance cust...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead the charge in delivering impactful customer experience consulting by analyzing complex data, mentoring junior consultants, and driving projects to successful, measurable results, all while ensuri...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $110K *

Lead the enablement program for customer-facing teams, ensuring they are equipped with the latest product knowledge and skills. Collaborate with Sales and CS leaders to create impactful training sessi...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$166K - $187K *

Empower patients by delivering high-quality, evidence-based primary care through innovative digital platforms. Collaborate with a diverse team to manage complex health needs and enhance patient outcom...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Provide comprehensive clinical care for individuals with substance use disorders, focusing on assessment, diagnosis, and treatment. Collaborate with interdisciplinary teams to ensure effective medicat...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.