Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$120K - $160K *

Accelerate progress at multiple travel centers by leading operational excellence and delivering outstanding guest experiences. Drive performance and develop high-performing teams while ensuring compli...

RemoteRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Energy & Utilities

$150K - $240K *

Develop innovative PCB layouts and improve product designs by collaborating with cross-functional teams. Ensure high quality and compliance throughout the engineering and manufacturing process, while...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$145K - $222K *

Drive structural engineering excellence by leading a talented team, guiding complex projects in nuclear facility design and analysis, and collaborating with clients to innovate sustainable energy solu...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Technical Services

$140K - $180K *

Accelerate your career by delivering innovative MuleSoft solutions that enhance API-led connectivity and integration within complex environments. Collaborate with diverse teams to transform requiremen...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$139K - $232K *

Unlock potential by providing enterprise architecture leadership for Corporate Functions, focusing on Finance and supporting areas. Shape technology strategies and roadmaps to enhance financial manage...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$160K - $200K *

Lead the charge in driving strategic growth by identifying opportunities, building partnerships, and enhancing market presence within federal agencies. Collaborate with teams to develop proposals and...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$159K - $212K *

Drive your career forward by leading strategic BESS augmentation projects. Oversee teams, manage budgets, and ensure safe, timely delivery of battery capacity enhancements while fostering collaboratio...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Energy & Utilities

$117K - $176K *

Innovate solutions as a key analyst in ERP, enhancing business operations through development, configuration, and support of enterprise applications while collaborating with cross-functional teams to...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$325K - $400K *

Drive the evolution of AI-native workflows by embedding with engineering teams, enhancing developer productivity, and defining impactful roadmaps directly aligned with company goals...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Champion customer success by owning relationships, driving adoption, and ensuring renewals. Leverage deep trust to generate qualified leads while proactively engaging law firm accounts to enhance thei...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Legal & Accounting

$185K - $226K *

Engage healthcare providers by promoting Copiktra, driving on-label sales growth through strategic territory planning and collaboration with cross-functional teams to meet customer needs and achieve s...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$200K - $220K *

Join a team that's redefining sales excellence by driving growth and nurturing client relationships. Leverage your expertise in technology sales to identify opportunities, manage forecasts, and articu...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$175K - $210K *

Drive revenue growth by leading a high-performing sales team, crafting strategic initiatives, and fostering customer relationships in a dynamic, fast-paced environment. Shape the future of a high-pote...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Drive efficient order management and logistics operations, ensuring compliance with pharmaceutical regulations while collaborating with internal teams and 3PL partners to optimize product flow and per...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a dynamic team as a Customer Success Manager, driving customer satisfaction and retention through tailored strategies. Collaborate with stakeholders to optimize product adoption and ensure client...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Transportation

$115K - $172K *

Shape the future of healthcare by leading complex data ingestion initiatives. Collaborate with cross-functional teams to drive program delivery, manage risks, and ensure operational excellence while t...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$160K - $200K *

Drive enterprise security architecture initiatives, collaborating with business leaders to design innovative solutions that enhance data protection and compliance across large-scale environments, ensu...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$98K - $163K *

Analyze fraud investigations and operational activities to ensure compliance, accuracy, and quality. Evaluate work products, identify trends, and support documentation and training development to enha...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$87K - $110K *

Join a team that's dedicated to advancing disability research, leading projects that enhance employment and social integration for individuals with disabilities. Collaborate with diverse stakeholders...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $130K *

Lead cross-functional IT projects, ensuring timely delivery and alignment with business goals. Manage project plans, risks, and stakeholder communication to drive successful outcomes and optimize reso...

Yesterday

  •   5 - 7 years exp.  •   Business Services

$86K - $111K *

Champion patient experience initiatives across healthcare facilities, driving service excellence and quality improvement. Collaborate with clinical teams to enhance patient satisfaction and foster a c...

Yesterday

  •   Less than 5 years exp.  •   Hospitality & Recreation

$125K - $150K *

Shape the future of clinical education by leading curriculum design, faculty development, and assessment strategies. Collaborate with key stakeholders to ensure high-quality instruction and compliance...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$200K *

Lead the charge in driving revenue growth and sales execution across the Central Region. Collaborate with Regional Directors to enhance leadership capabilities and ensure exceptional patient experienc...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$135K - $150K *

Unlock the potential of critical data systems by administering and optimizing database environments. Collaborate with cross-functional teams to ensure performance, security, and reliability in healthc...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Innovate the future of customer experience by leading strategic partnerships and driving transformation in AI-driven solutions. Shape commercial strategies that bridge legacy systems with modern, imme...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Telecommunications & Hardware

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.