Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$110K - $130K *

Lead the administration and engineering of a robust Snowflake data platform, ensuring security, performance, and reliability. Design data pipelines and enable AI applications, driving innovation and s...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $120K *

Drive specialized pulmonology care for adults in a collaborative outpatient setting, managing diverse respiratory conditions while ensuring high-quality patient interactions and support within a dedic...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Lead the integration agenda for Customer Development, driving alignment across functions and ensuring successful execution of complex initiatives while managing risks and dependencies...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Food & Beverages

$114K - $252K *

Join a team that's shaping the future of AI by developing and supporting innovative workflows and agents on an enterprise platform, ensuring seamless integration and high-quality performance in secure...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Information Technology

$58K - $115K *

Advance geospatial solutions by developing and enhancing ArcGIS applications for transportation management. Collaborate with a dynamic team to support critical defense operations through innovative ma...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$90K - $189K *

Elevate your career as a Test Engineer, driving quality assurance for enterprise IT services. Collaborate with teams to implement automated testing frameworks, ensuring high standards and seamless int...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Information Technology

$68K - $114K *

Lead the charge in designing and implementing assessment tools that enhance talent acquisition and management strategies, collaborating with key stakeholders to optimize hiring processes and ensure eq...

Reposted yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$87K - $154K *

Lead the charge in strategic sourcing for Marketing initiatives, driving supplier engagement in print and mail services. Collaborate cross-functionally to optimize contract negotiations and enhance su...

Reposted yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$119K - $224K *

Accelerate your career by leading custom credit solutions for high-net-worth clients. Collaborate with a dynamic team to structure complex transactions and drive innovative financial strategies in the...

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$99K *

Engage in Treasury Management support by analyzing client needs, identifying process improvements, and collaborating with stakeholders to enhance operational efficiency while ensuring compliance with...

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Unlock potential by leading user acceptance testing for AI and automation initiatives. Collaborate across teams to ensure solutions meet business needs and compliance standards, driving efficiency and...

Reposted yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$139K - $260K *

Advance legal strategies by providing expert counsel to the Merchant Services team, ensuring compliance with regulations and supporting product development initiatives while collaborating with various...

Reposted yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$87K - $154K *

Lead the charge in optimizing talent selection and assessment processes. Collaborate with stakeholders to design and implement tools that enhance hiring quality and support employee development across...

Reposted yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$77K - $121K *

Lead the charge in managing complex commercial loan closings, ensuring compliance and accuracy while collaborating with cross-functional teams to mitigate risks and enhance operational efficiency...

Reposted yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$175K - $270K *

Advance client relationships by identifying growth opportunities and leading the sales cycle. Collaborate cross-functionally to design solutions that meet client needs and drive revenue, ensuring long...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Business Services

$95K - $123K *

Redefine HR compliance by leading programs that ensure adherence to federal, state, and local regulations. Collaborate with cross-functional teams to enhance operational effectiveness and mitigate com...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Energy & Utilities

$120K - $145K *

Lead the charge in developing high-performance, secure cloud components while collaborating with stakeholders to enhance data products and mentor junior engineers in an agile environment...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$196K - $294K *

Empower the EMD franchise by leading learning strategies and operational execution, driving measurable impact across commercial, medical, and market access teams while fostering a high-performing cult...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$268K - $402K *

Champion the epilepsy pipeline by leading global medical strategies, ensuring regional insights drive clinical development and evidence generation. Collaborate across teams to address healthcare needs...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$196K - $294K *

Unlock potential by leading innovative learning strategies for the Sleep franchise, driving operational excellence and measurable impact across commercial, medical, and market access teams while foste...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$78K - $88K *

Optimize your career by developing innovative AI/ML applications. Collaborate with diverse teams to enhance software tools that drive sales effectiveness and efficiency. Contribute to the entire softw...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$135K - $155K *

Innovate cutting-edge firmware solutions for advanced video security products. Collaborate with cross-functional teams to design, develop, and enhance embedded systems, ensuring high-quality performan...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$112K - $135K *

Join a team that's innovating healthcare solutions by developing cutting-edge network messaging software. Collaborate with diverse engineers to enhance patient experiences while enjoying a positive wo...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$134K - $168K *

Join a team that's transforming operational data into reliable customer experiences. As a Senior Machine Learning Engineer, you'll lead the development of innovative machine learning solutions, enhanc...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$94K - $120K *

Elevate your career by leading the optimization of EMR applications, enhancing laboratory workflows, and ensuring efficient patient care delivery through collaboration with clinical and technical team...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.