Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,075

Sort By: Relevance

$130K - $160K *

Advance your leadership in human resources by driving culture, wellbeing, and compliance strategies. Collaborate across teams to enhance HR capabilities, support team members, and achieve organization...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $162K *

Join a team that's redefining digital banking solutions by providing expert consultation and driving value-based technical strategies. Collaborate with peers to enhance product development and optimiz...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$57K - $108K *

Empower the development of cutting-edge flight control systems as you apply your software engineering skills to real-time embedded systems with critical safety requirements in a collaborative team env...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $130K *

Oversee the design and development of clinical databases while ensuring project timelines and quality standards are met. Collaborate across teams to provide technical support and mentor team members...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$73K - $102K *

Unlock potential by leading SAP ABAP development initiatives, driving innovative solutions, and collaborating with teams to enhance client operations. Your expertise will shape the future of technolog...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Elevate network operations by leading complex incident responses and mentoring teams. Collaborate with cross-functional partners to enhance network reliability and operational maturity across global e...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$125K - $150K *

Strategize with senior leadership to shape and execute People strategy, driving organizational design and employee relations. Lead initiatives that align talent with business goals during a critical g...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$70K - $100K *

Drive your career forward by managing key partnerships and delivering measurable results. This role blends strategic relationship management with consultative selling, ensuring partner success and gro...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Innovate at the forefront of data analytics by driving technical presales, engaging with customers, and delivering tailored solutions that enhance business agility and insights. Collaborate with cross...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$85K - $115K *

Engage clients by managing innovative programs that enhance energy solutions. Drive success through strong relationships, effective communication, and strategic problem-solving while collaborating wit...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$80K - $95K *

Join a dynamic team to oversee clinical research activities, ensuring compliance with regulatory standards and driving site performance. Collaborate with stakeholders to enhance patient safety and dat...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$164K - $262K *

Advance your career by designing and operating AI systems for mortgage Fulfillment. Lead architecture, build evaluation frameworks, and ensure reliability while collaborating with cross-functional tea...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$130K - $192K *

Join a team that's implementing robust security controls across multiple brands, safeguarding employees and enhancing productivity through automation and secure practices. Collaborate globally while l...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$160K - $200K *

Join a team that's redefining forensics and collections globally. Lead a skilled team, enhance operational efficiency, and drive client engagement while ensuring compliance and defensibility across re...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Legal & Accounting

$80K - $95K *

Empower frontline workers by owning the full sales cycle in a dynamic team. Drive impactful solutions, build relationships, and refine strategies to scale success in a fast-paced environment. Your con...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Advance customer engagement in banking by executing product strategies and managing CRM solutions. Collaborate with cross-functional teams to enhance customer relationships and drive measurable value...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $176K *

Lead the charge in driving strategic growth and retention for global key accounts. Collaborate across functions to enhance customer relationships and execute multi-year account strategies that align w...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Food & Beverages

$185K - $200K *

Empower engineering excellence by leading backend teams to deliver scalable, reliable systems that enhance member experiences. Drive strategic initiatives, foster talent, and optimize processes for a...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$104K - $156K *

Accelerate your career by leading KPI design and governance, partnering with business leaders to translate strategic priorities into measurable outcomes, and driving accountability for performance imp...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$80K - $95K *

Join us to develop and implement complex financial analyses, ensuring accurate reporting and forecasting. Collaborate across business areas to enhance financial performance and support strategic decis...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$130K - $150K *

Accelerate strategic partner growth through visionary sales leadership, driving revenue and pipeline expansion while cultivating dynamic relationships and actionable growth strategies. Own the partner...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$160K - $201K *

Shape the future of global disputes management by leading a dynamic team focused on employment and litigation matters across diverse jurisdictions. Drive strategic initiatives while collaborating with...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $160K *

Accelerate your career by driving business development in the biotech sector. Build relationships, consult on data solutions, and enhance sales opportunities while collaborating with cross-functional...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$50K - $150K *

Unlock potential by driving sales and building relationships with clients. Manage a pipeline from outreach to close, collaborate with teams, and exceed performance goals while representing the brand w...

2 weeks ago

  •   Less than 5 years exp.  •   Transportation

$340K *

Elevate your career by driving strategic sales in the TOLA region. Collaborate with cross-functional teams to build relationships, uncover opportunities, and deliver value through innovative SaaS solu...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.