Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,075

Sort By: Relevance

$93K - $125K *

Join a dynamic team as a technical resource, enhancing enterprise applications and infrastructure services. Drive operational excellence, support cross-functional initiatives, and ensure reliable, sec...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $210K *

Unlock the potential of Higher Education by designing and implementing Workday Grants Management solutions. Collaborate with mission-driven organizations to ensure accuracy and long-term success in gr...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$110K - $151K *

Champion operational excellence by ensuring radiation safety and EHS compliance across cyclotron manufacturing and PET nuclear pharmacy facilities in the South Central US, while collaborating with cro...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Elevate customer relationships by owning a strategic account portfolio, driving growth through consultative selling and collaboration across teams. This senior role demands proactive engagement and a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Elevate operational excellence by standardizing workflows and driving accountability across multiple sites. Lead a high-performing team to ensure consistent patient access and optimize performance met...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$230K - $260K *

Redefine global compensation and benefits strategies to attract AI talent, ensuring fairness and scalability across 18 countries while collaborating with executives and leveraging AI for innovative re...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Join a team that's dedicated to providing exceptional remote technical support for complex issues across our product lines. Collaborate with peers to resolve challenges and ensure customer satisfactio...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead the charge in enhancing cloud security by conducting proactive reviews, managing complex incidents, and collaborating with cross-functional teams to improve detection and response mechanisms whil...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $88K *

Transform the claims process by analyzing Lost-Time Workers Compensation claims, ensuring timely resolutions while delivering exceptional service to clients across various industries. Join a dynamic t...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $170K *

Transform community health by providing comprehensive primary care services. Engage with diverse patient populations, manage chronic conditions, and collaborate with a dedicated team in a supportive e...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $170K *

Accelerate financial management for high-impact health research programs. Collaborate with diverse teams to develop budgets, analyze expenditures, and ensure compliance with federal regulations, drivi...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$165K - $185K *

Accelerate progress at the forefront of test automation, driving quality and performance through innovative strategies and frameworks. Collaborate within an agile team to enhance product scalability a...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$97K - $137K *

Transform quality assurance processes by leading automation testing initiatives, mentoring teams, and developing strategic test plans to ensure robust web-based applications meet user requirements and...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$231K - $340K *

Partner with us to drive sales of innovative cybersecurity solutions, cultivating strong client relationships and exceeding quotas in the TOLA territory. Leverage your expertise to deliver impactful s...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$115K - $143K *

Unlock the potential of data by architecting scalable pipelines and driving analytics initiatives, mentoring engineers, and collaborating with cross-functional teams to enhance our data solutions in a...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $100K *

Champion your expertise to drive and optimize innovative commerce media strategies, ensuring client satisfaction and measurable success across diverse marketing channels in a fully remote environment...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$80K - $100K *

Optimize marketing campaigns within the commerce media ecosystem, developing tailored omnichannel strategies to drive client success and satisfaction while leveraging data-driven insights for continuo...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$73K - $115K *

Unlock the potential of clinical documentation integrity by driving ICD-10-CM coding accuracy and enhancing provider education. Collaborate with cross-functional teams to support risk adjustment initi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$58K - $107K *

Manage and oversee Short-Term Disability claims and leave requests, ensuring compliance with regulations while supporting employees' return-to-work strategies through effective case management and com...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $173K *

Transform data acquisition processes by leading the development of high-performance ingestion pipelines. Collaborate across teams to ensure data quality, reliability, and security while shaping the fu...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$105K - $124K *

Lead a dynamic team of sales professionals to drive growth in expense management solutions. Collaborate on strategy, nurture talent, and exceed sales goals while engaging with customers and bridging t...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$77K - $101K *

Execute strategic sales initiatives to drive growth in expense management solutions, engaging existing clients to enhance their financial operations through innovative payment processing and expense m...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$122K - $177K *

Unlock potential by leading HRIS strategy and optimization, overseeing a team to enhance Workday and UKG systems. Drive transformation and collaboration across HR, Finance, and Operations for impactfu...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in managing complex projects within the pharmaceutical and biotech sectors, ensuring successful execution and delivery while mentoring teams and collaborating with stakeholders to achi...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$246K - $332K *

Shape the future of health economics and outcomes research by leading strategic initiatives across the nephrology portfolio, ensuring high-quality evidence generation and collaboration with cross-func...

RemoteRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.