Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,075

Sort By: Relevance

$135K - $160K *

Join us to lead innovative Oracle Cloud solutions, collaborating with clients to design and deliver cutting-edge technical architectures that address complex business challenges and drive success in a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$136K - $160K *

Drive global procurement strategies and foster client relationships while overseeing multi-regional teams. Lead sourcing initiatives, ensure compliance, and deliver measurable value aligned with clien...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Elevate your career by building strategic partnerships with top clients, driving renewals and upsells. Own the sales process and collaborate with teams to ensure exceptional service and satisfaction w...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $110K *

Transform field support by leveraging expertise to enhance customer satisfaction, drive product improvements, and lead training initiatives. Collaborate with R&D and field teams to ensure optimal perf...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $90K *

Grow your career with a dynamic team providing intensive outpatient therapy for older adults. Collaborate with healthcare professionals to deliver compassionate mental health support, focusing on grou...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$89K - $148K *

Elevate financial management and audit remediation efforts for DoD clients, leveraging expertise in accounting, internal controls, and compliance to drive strategic improvements and ensure adherence t...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$197K - $239K *

Join us to lead AI-driven innovation in real-world data strategy, translating business priorities into actionable insights. Drive data intelligence and collaboration across teams to enhance evidence g...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $130K *

Champion quality and commissioning excellence across diverse construction projects, ensuring compliance and safety while fostering collaboration among teams and stakeholders to drive impactful results...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $190K *

Innovate scalable, cloud-native APIs with .NET and Java/Kotlin. Lead architecture discussions, enhance core offerings, and collaborate across teams to deliver high-value system components in a dynamic...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Transportation

$120K - $170K *

Elevate enterprise service reliability by leading Major Incident Management and supporting operational excellence across monitoring and incident response functions in a dynamic, 24x7 environment...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Empower teams by designing and delivering automation solutions that streamline workflows, enhance operational efficiency, and support scalable applications across hybrid cloud environments. Join us in...

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$90K - $115K *

Explore a strategic leadership role focused on developing omnichannel engagement strategies that connect media, analytics, and customer experiences, driving measurable outcomes for healthcare brands a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$199K - $285K *

Empower enterprise transformation by leading strategic initiatives and engaging with C-level executives. Collaborate cross-functionally to drive revenue and deliver impactful workshops that showcase i...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$93K - $125K *

Join a dynamic team as a technical resource, enhancing enterprise applications and infrastructure services. Drive operational excellence, support cross-functional initiatives, and ensure reliable, sec...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $210K *

Unlock the potential of Higher Education by designing and implementing Workday Grants Management solutions. Collaborate with mission-driven organizations to ensure accuracy and long-term success in gr...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$110K - $151K *

Champion operational excellence by ensuring radiation safety and EHS compliance across cyclotron manufacturing and PET nuclear pharmacy facilities in the South Central US, while collaborating with cro...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Elevate customer relationships by owning a strategic account portfolio, driving growth through consultative selling and collaboration across teams. This senior role demands proactive engagement and a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Elevate operational excellence by standardizing workflows and driving accountability across multiple sites. Lead a high-performing team to ensure consistent patient access and optimize performance met...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$230K - $260K *

Redefine global compensation and benefits strategies to attract AI talent, ensuring fairness and scalability across 18 countries while collaborating with executives and leveraging AI for innovative re...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Join a team that's dedicated to providing exceptional remote technical support for complex issues across our product lines. Collaborate with peers to resolve challenges and ensure customer satisfactio...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead the charge in enhancing cloud security by conducting proactive reviews, managing complex incidents, and collaborating with cross-functional teams to improve detection and response mechanisms whil...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $88K *

Transform the claims process by analyzing Lost-Time Workers Compensation claims, ensuring timely resolutions while delivering exceptional service to clients across various industries. Join a dynamic t...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $170K *

Transform community health by providing comprehensive primary care services. Engage with diverse patient populations, manage chronic conditions, and collaborate with a dedicated team in a supportive e...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $170K *

Accelerate financial management for high-impact health research programs. Collaborate with diverse teams to develop budgets, analyze expenditures, and ensure compliance with federal regulations, drivi...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$165K - $185K *

Accelerate progress at the forefront of test automation, driving quality and performance through innovative strategies and frameworks. Collaborate within an agile team to enhance product scalability a...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.