Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$73K - $182K *

Innovate design concepts while leading and mentoring a dynamic team. Collaborate cross-functionally, present ideas to clients, and drive strategic insights for impactful brand development across multi...

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$120K - $160K *

Transform real estate opportunities by leading market evaluations, strategic planning, and cross-functional collaboration to optimize portfolio growth and cost management across multiple regions...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$180K - $220K *

Drive the product vision and strategy for integrated hardware and software ecosystems, overseeing complex technology development while leading a team of Product Managers to achieve growth and innovati...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Transportation

$70K - $105K *

Collaborate with cross-functional teams to drive project execution and operational excellence in medical communications. Leverage your project management skills to ensure timely delivery and high-qual...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Inspire and elevate design excellence as you lead a talented team, setting and maintaining visual standards, driving innovative campaigns, and partnering cross-functionally to advance Dandy's brand an...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $115K *

Unlock potential by providing vital sales support and presentations, driving customer integration and product utilization, while conducting market research to enhance offerings. Collaborate closely wi...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $230K *

Pioneer innovative oncology solutions by building strong relationships with key stakeholders, driving product adoption, and exceeding performance goals in a dynamic biopharma environment focused on pa...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$272K - $374K *

Empower our sales team to drive revenue growth by leading strategic engagements with Federal Systems Integrators. Utilize your expertise to craft account plans, build relationships, and navigate compl...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $120K *

Grow your career with a dynamic sales role, driving supply chain transparency for leading brands. Own the full sales cycle, engage senior stakeholders, and develop solutions that enhance customer valu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$103K - $141K *

Take ownership of customer success by driving adoption and value realization of the platform. Leverage your technical expertise to guide clients through onboarding and operationalization, ensuring sat...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K *

Unlock potential by driving enterprise account strategies and engaging technical leaders. Collaborate with AEs to create meaningful outreach and build a pipeline that converts, focusing on quality int...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$183K - $230K *

Lead the charge in shaping our platform strategy, overseeing integrations, pricing, and customer experience. Collaborate with cross-functional teams to enhance product offerings and drive growth in a...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $130K *

Drive the Insider Threat Program by leading complex investigations, analyzing risks, and enhancing detection capabilities. Collaborate with cross-functional teams to mitigate insider threats and stren...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Unlock potential by leveraging your GI expertise to enhance product development, strengthen customer relationships, and drive growth in a dynamic SaaS environment. Collaborate across teams to deliver...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Shape the future of client strategy by leading growth initiatives, managing relationships, and driving performance metrics. Collaborate across teams to enhance brand success and ensure seamless execut...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Media

$130K - $241K *

Empower organizations to enhance sales effectiveness by designing and implementing robust Sales Performance Management solutions while leading teams and driving business development initiatives in a d...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Develop and execute innovative product strategies for a global Oil-Flooded compressor portfolio, driving profitable growth through customer insights and cross-functional collaboration to enhance marke...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Inspire excellence in nursing care by leading clinical teams to achieve high-quality standards. Drive positive change, foster a supportive culture, and ensure that residents receive top-tier care tail...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$85K - $95K *

Empower your career as a full-cycle Recruiter, managing diverse hiring needs across sales, IT, marketing, admin, and operations. Collaborate with hiring managers to attract top talent and enhance cand...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Take ownership of complex institutional partnerships, driving customer success and retention. Collaborate cross-functionally to enhance account growth, manage contracts, and optimize platform implemen...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$313K - $365K *

Unlock potential by shaping the future of consumer insights through advanced data science. Lead measurement and modeling strategies to enhance user engagement and community dynamics, driving impactful...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$120K - $140K *

Contribute to innovative performance marketing strategies driving customer acquisition and retention. Manage budgets, conduct experiments, and leverage AI tools to optimize campaigns across multiple d...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$106K - $284K *

Champion the design and development of scalable applications, integrating AI and data systems. Lead technical strategy, mentor teams, and ensure operational excellence across the technology stack whil...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $170K *

Contribute to performance optimization by diagnosing shifts in a $30B portfolio. Leverage data insights to drive strategic recommendations, enhance client outcomes, and collaborate with cross-function...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Unlock your potential by managing key accounts in the pet food industry. Collaborate with diverse brands to drive growth, enhance customer relationships, and execute strategic plans that improve pet h...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.