Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,075

Sort By: Relevance

$80K - $95K *

Transform control systems for food and beverage plants by designing, programming, and implementing PLC/HMI solutions. Collaborate with teams to enhance manufacturing processes and deliver innovative a...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$95K - $130K *

Lead the charge in backlog management and agile ceremonies, translating stakeholder needs into prioritized tasks. Collaborate across squads to ensure delivery quality and stakeholder satisfaction whil...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Partner with us to drive sales in the Neurosurgery product line, achieving revenue targets through strategic planning, relationship building, and exceptional customer service in a dynamic operating ro...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $156K *

Transform the product marketing landscape by executing strategic go-to-market plans, ensuring cohesive messaging across athenaOne offerings. Collaborate with cross-functional teams to drive market und...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Empower digital transformation by leading Drupal modernization initiatives, guiding architecture strategies, and enhancing enterprise web platforms for improved performance, security, and user experie...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$160K - $190K *

Advance product strategy and innovation by leading cross-functional teams to drive the vision, roadmap, and delivery of shared commercial platforms, ensuring alignment with business priorities and tec...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$149K - $298K *

Lead strategic and operational initiatives for field clinical teams, ensuring compliance and effective trial support for TMVR programs while driving positive patient outcomes and team performance...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$145K - $175K *

Champion the strategic growth of our North America insurance program, leading teams to enhance client retention and drive profitability. Collaborate with partners to ensure compliance and operational...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$154K - $185K *

Empower the development of scalable observability systems, driving projects from concept to operation. Collaborate with a remote team to enhance performance and reliability while contributing to open...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$200K - $240K *

Join a dynamic team as you provide technical expertise, drive enterprise opportunities, and architect innovative solutions that meet client needs while showcasing the value of our cutting-edge product...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$67K - $111K *

Deliver compassionate, expert behavioral health care throughout members' journeys, ensuring clinical excellence in a fast-paced, 24/7 environment as a trusted clinical partner in diverse cases and sup...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $130K *

Join a dynamic team to design and optimize scalable data solutions that enhance healthcare technology platforms. Collaborate with cross-functional teams to ensure data integrity and drive informed dec...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$103K - $123K *

Drive growth by managing a sales territory, building relationships, and generating premium. Leverage existing partnerships while prospecting new agencies to achieve targets and expand market presence...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Champion your career by leading a diverse team to deliver innovative technical solutions across multiple platforms, ensuring quality and security in a fast-paced environment while managing complex pro...

2 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$110K - $130K *

Lead a diverse team of technology professionals to deliver innovative, secure solutions across multiple platforms, ensuring timely execution of complex projects while maintaining high performance and...

2 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$63K - $105K *

Champion the development of AI agents and workflows, leveraging GenAI.mil to create innovative automated solutions. Collaborate with cross-functional teams to enhance processes and deliver high-qualit...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$69K - $93K *

Join a dynamic team as you leverage your technical expertise to drive customer success in IoT solutions. Engage with diverse industries, providing tailored support and fostering relationships that enh...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $125K *

Deliver exceptional customer success through effective engagement, relationship-building, and proactive problem-solving for complex district implementations. Collaborate with teams to ensure portfolio...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Shape the visual identity of our brand by evolving design systems, creating impactful marketing materials, and collaborating across teams to ensure cohesive brand representation in all digital and phy...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$165K - $175K *

Champion strategic people initiatives by advising leadership, crafting executive communications, and leveraging analytics to drive organizational effectiveness and accountability across the People fun...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Advance patient care in a collaborative healthcare environment. As a Nurse Practitioner, you'll assess, diagnose, and treat patients while coordinating care across multiple programs, ensuring high-qua...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Join a team that's driving growth by executing strategic sales plans and expanding distribution networks. Collaborate with contractors and retail customers to enhance market presence and deliver tailo...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Lead the charge in shaping product strategy for fraud detection, collaborating across teams to deliver impactful solutions. Drive innovation while ensuring reliability and user experience in a fast-pa...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $140K *

Unlock potential by driving SBA loan origination and fostering partnerships in targeted sectors. Join a dynamic team focused on revenue growth and relationship development through your established net...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Drive success by leading sales and marketing strategies across multiple properties, enhancing occupancy and revenue while fostering key client relationships and managing a dynamic team in a competitiv...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.