Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Average Salary: $110,016
Senior Manager, Virtual Fundraising (Remote)
$80K - $95K *
Join a team that's redefining virtual fundraising by leading innovative campaigns that engage diverse audiences, cultivate partnerships, and drive sustainable revenue growth, all while supporting a me...
1 week ago
Enterprise Architect - Data & Employee Systems (Databricks)
$150K - $170K *
Unlock the potential of enterprise data architecture by designing secure, scalable solutions for employee data using Databricks. Collaborate with cross-functional teams to implement governance, compli...
1 week ago
New Business Sales Executive - Western Territory
$100K - $120K *
Drive revenue growth by cultivating relationships and managing the full-cycle sales process in the healthcare technology sector. Utilize AI-driven solutions to enhance client performance and deliver v...
1 week ago
$80K - $95K *
Join a team that's transforming client websites into growth engines through data-driven conversion rate optimization. Collaborate with cross-functional experts to analyze user behavior, run A/B tests...
1 week ago
Lead Financial Analyst - Capital Reporting (Hybrid)
$94K - $110K *
Shape financial strategies by providing expert analysis and insights into capital generation. Collaborate with cross-functional teams to enhance reporting and drive process improvements while mentorin...
1 week ago
$100K - $120K *
Optimize customer engagement by leveraging technical expertise to drive sales, enhance relationships, and expand market share for pneumatic and control systems. Collaborate with teams to deliver tailo...
1 week ago
Senior Manager / Associate Director, Medical Information
$165K - $210K *
Drive the Medical Information strategy for infigratinib, ensuring high-quality, compliant content delivery. Collaborate cross-functionally to support scientific exchange and operational excellence in...
1 week ago
$80K - $95K *
Transform customer relationships and drive revenue growth by managing account strategies, identifying upsell opportunities, and collaborating with cross-functional teams to enhance product adoption an...
Reposted 1 week ago
$75K - $90K *
Empower your career by joining a dedicated clinical team providing psychological services in long-term care. Enjoy professional autonomy, a flexible schedule, and robust support while making a meaning...
1 week ago
$120K - $175K *
Pioneer insights at the intersection of Sales, Marketing, and CS by owning and enhancing analytical infrastructure to generate decision-ready insights that drive growth in a dynamic, fast-paced enviro...
Reposted 1 week ago
Sr. Advisor, Molecular Pharmacology - Neuroscience
$129K - $231K *
Reimagine drug discovery as you lead molecular pharmacology efforts in neuroscience. Collaborate across teams to develop strategies, interpret data, and advance innovative therapies for sleep-wake dis...
Reposted 1 week ago
$80K - $105K *
Join a specialized team to evaluate biological research, ensuring safety against misuse. Utilize your expertise to distinguish legitimate science from potential threats, contributing to AI safety and...
1 week ago
Senior Staff Engineer, Design Systems
$135K - $160K *
Join a dynamic team to architect and implement a next-gen Design System, ensuring consistent, accessible experiences across products. Collaborate with cross-functional teams to drive technical alignme...
1 week ago
Director, Access Strategy & Marketing
$201K - $251K *
Elevate access strategies and marketing initiatives for oncology products, focusing on non-clinical value propositions. Collaborate cross-functionally to ensure successful product launches and effecti...
1 week ago
Executive Director Access Services - Immunology
$255K - $424K *
Lead the development and execution of Immunology access services strategy, ensuring seamless patient and provider experiences. Collaborate cross-functionally to enhance reimbursement initiatives and d...
1 week ago
$80K - $95K *
Join a dynamic team as you drive continuous improvement initiatives, enhancing operational efficiency and fostering a culture of excellence across the organization. Collaborate with cross-functional t...
1 week ago
$142K - $160K *
Champion privacy compliance in the Neurology therapeutic area, providing expert guidance on data protection, contract negotiation, and training. Collaborate with cross-functional teams to ensure adher...
1 week ago
Territory Sales Representative, Dental Implants
$70K - $150K *
Drive growth in oral surgery practices by building relationships, pursuing new sales opportunities, and achieving targets. Leverage your sales expertise to deliver exceptional customer service and sup...
1 week ago
Nuclear Engineering Manager - Electrical / I&C
$130K - $155K *
Advance your career by leading engineering teams in the critical restoration and operational readiness of a nuclear facility, ensuring compliance and technical excellence while driving Iowa's clean en...
Reposted 1 week ago
Patient Access Liaison - Remote
$110K - $130K *
Join us to minimize access barriers for patients and providers, executing market access plans across multiple states. Collaborate with healthcare professionals to resolve reimbursement issues and enha...
1 week ago
$150K - $350K *
Join a team that's building scalable, high-performance backend systems using TypeScript. Collaborate across functions to optimize trading solutions and tackle complex challenges in the blockchain spac...
1 week ago
Oracle Utilities Field Service Solution Architect
$120K - $145K *
Empower your career by leading the design and implementation of Oracle Field Service solutions for utility organizations. Collaborate with stakeholders to enhance operational performance and customer...
1 week ago
Enterprise Customer Success Manager
$110K - $130K *
Unlock potential by overseeing a portfolio of enterprise accounts, fostering strategic partnerships, and driving user engagement to achieve measurable outcomes. Collaborate with internal teams to deli...
1 week ago
Sr. Director, Marketing Strategy, Analytics & Innovation
$227K - $335K *
Empower growth through strategic marketing leadership, leveraging data insights to drive customer engagement and revenue. Build and mentor a high-performing team to transform analytics into actionable...
1 week ago
Associate Director - Clinical Operations - Healthcare
$155K - $259K *
Transform healthcare performance by leading integrated optimization programs that enhance clinical, operational, and financial outcomes for hospitals and health systems. Drive measurable results throu...
1 week ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.