Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$212K - $287K *

Transform the Hematology landscape by leading a high-performing sales team, driving strategic initiatives, and ensuring compliance while exceeding sales objectives in the Great Plains region...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$184K - $356K *

Drive technical engagement with telecom accounts, connecting customer workloads to NVIDIA's ecosystem. Serve as a trusted advisor, co-design scalable architectures, and lead technical enablement to en...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$145K - $170K *

Join us to drive strategic sales initiatives, leveraging a robust resource model and tech stack to achieve performance goals and maximize customer value in a dynamic, collaborative environment...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $90K *

Transform the claims landscape by managing commercial property claims, collaborating with diverse teams, and enhancing your expertise in global and excess lines. Join a dynamic environment focused on...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Empower the CDL program by leading training initiatives, ensuring compliance, and optimizing fleet management. Collaborate with regional leaders to enhance operational efficiency and drive revenue gro...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$135K - $160K *

Lead the charge in developing and executing CMC strategies for antibody-based radiopharmaceuticals, ensuring alignment with Stage-Gate requirements while managing cross-functional teams and external p...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$112K - $189K *

Lead the charge in delivering exceptional pharmaceutical care by interpreting prescriptions, consulting with patients, and ensuring quality assurance. Collaborate with healthcare professionals to opti...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Empower developers by diagnosing and resolving complex technical issues related to APIs. Collaborate across teams, advocate for improvements, and enhance developer experiences in a fast-paced, innovat...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $110K *

Join a dynamic team to develop and enhance SaaS applications, utilizing Agile methodologies. Collaborate with peers, support customers, and drive innovative solutions while staying updated on technica...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$68K - $131K *

Join our team as you contribute to the development of innovative display products. Collaborate with cross-functional teams to meet project goals while enhancing processes and ensuring quality througho...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$65K - $96K *

Advance leadership development by designing impactful programs and coaching talent. Collaborate with teams to enhance learning experiences and drive measurable success in succession planning and organ...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $196K *

Shape the future of K-12 education by leading product marketing strategies that drive growth and adoption. Collaborate cross-functionally to deliver compelling messaging and go-to-market initiatives t...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$170K - $210K *

Elevate project management excellence by leading design coordination for OFCI mechanical systems in a dynamic data center environment, ensuring seamless integration and adherence to technical standard...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$116K - $165K *

Lead the design and integration of marine electrical systems for commercial and governmental vessels. Ensure compliance with regulatory standards while managing technical responsibilities for shipboar...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Advance your career by leading multi-team oversight and management in accounting operations across diverse industries. Utilize your expertise in compliance, software integration, and project managemen...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$72K - $112K *

Serve as a vital link in healthcare by providing expert technical support for imaging equipment. You'll ensure optimal performance through installation, troubleshooting, and maintenance, while fosteri...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$73K - $132K *

Lead strategies to optimize facility operations, ensuring safety and efficiency. Manage maintenance teams, oversee critical assets, and drive continuous improvement to deliver reliable supply chain so...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$80K - $83K *

Optimize electrical systems by troubleshooting, diagnosing, and repairing equipment. Collaborate with diverse teams to enhance safety and compliance while driving continuous improvement in a dynamic p...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$82K - $123K *

Champion AI innovation by driving tool adoption, engineering practices, and workforce enablement across the enterprise. Collaborate with cross-functional teams, influencing leaders and building future...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$71K - $119K *

Drive customer success by leveraging expertise in intellectual property solutions, enhancing product adoption, and delivering exceptional experiences through strategic engagement and training initiati...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$113K - $188K *

Contribute to innovative Salesforce solutions by leveraging your development expertise. Collaborate with cross-functional teams to design, build, and maintain scalable applications, ensuring high perf...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$74K - $124K *

Drive innovation by enhancing Power Platform tools for executive-level operations. Manage full lifecycle processes, ensuring compliance and improving operational efficiency through workflow automation...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$151K - $237K *

Transform healthcare outcomes by engaging with KOLs and HCPs, analyzing scientific data, and fostering expert networks. Drive medical strategy and enhance patient care through compliant, insightful co...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead the charge in overseeing a national Audit & Compliance team, ensuring regulatory adherence, risk management, and operational excellence while driving process improvements and fostering cross-func...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$90K - $100K *

Join a team that's redefining the Fine & Decorative Arts landscape. Drive strategic growth by transforming buyer demand into actionable supply opportunities, enhancing seller partnerships, and optimiz...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.