Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$125K - $150K *

Transform data integration in modern data centers by leading a team to design and implement edge collectors, ensuring seamless connectivity and efficient onboarding across multiple sites while collabo...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$195K - $230K *

Join a team that's redefining partnership development in the fintech space. You'll drive new opportunities with PSPs and banks, managing complex deals and collaborating cross-functionally to enhance C...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$216K - $361K *

Elevate your career by driving sales growth in enterprise software across retail, energy management, and telecommunications. Collaborate with top clients to achieve strategic goals and expand market p...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Transform nursing services by overseeing quality care for residents, managing a dedicated team, and ensuring compliance with health standards. Lead with passion and expertise in a supportive environme...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Lead the nursing team in delivering exceptional care to residents while overseeing operations and ensuring quality standards. This role offers mentorship and growth opportunities in a supportive envir...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Lead the charge in delivering exceptional oncology care as a Nurse Manager. Oversee infusion staff, provide direct patient care, and collaborate on healthcare delivery processes while shaping departme...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$148K - $201K *

Join us to shape the future of secure software delivery by developing AI-driven workflows and orchestrating complex systems. Collaborate with cross-functional teams to create intuitive solutions that...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$91K - $122K *

Empower and lead a high-performing sales team to exceed targets, fostering strategic relationships and guiding consultative sales strategies that highlight key market differentiators for sustained gro...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$120K - $185K *

Transform the future of engineering design by leading diverse teams to deliver high-quality electrical engineering solutions. Drive project success through strategic oversight, mentoring, and adherenc...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$135K - $145K *

Drive innovative software solutions by developing robust, cloud-native systems that enhance provider data management capabilities and meet the evolving needs of clients in a dynamic, collaborative env...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $140K *

Unlock potential by joining a dynamic team that enhances naval supply systems through application engineering, integration, and support. Collaborate with partners to refine requirements and ensure sys...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Join us to lead strategic projects in speech and audio, driving high-quality data programs for AI. You'll manage complex workflows, enhance client communication, and ensure quality standards in a rapi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$204K - $290K *

Manage the Resilience Engineering team to enhance system reliability through production load testing and chaos engineering while fostering a proactive safety culture across engineering practices...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Join a team that's redefining operational excellence in healthcare. This role drives performance and compliance across call center operations, enhancing efficiency and quality through strategic planni...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $121K *

Shape your career by leading a dynamic team in Operations, ensuring client satisfaction and effective implementation of Web Pay Products. Drive success through coaching and problem-solving in a fully...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$110K - $130K *

Join a team that's dedicated to enhancing client relationships and driving success. Oversee client performance, mentor staff, and ensure compliance while collaborating with various departments to deli...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $105K *

Join a dynamic team to drive the development and execution of innovative customer enablement programs. Lead cross-functional initiatives, establish operational excellence, and measure performance to e...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$80K - $95K *

Drive procurement excellence by overseeing purchasing activities, managing supplier relationships, and ensuring timely delivery of materials to meet production needs while optimizing costs and quality...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $214K *

Innovate and lead strategic partnerships in the HCM and WFM sectors, driving joint solutions and aligning cross-functional teams to enhance product offerings and deliver exceptional value to customers...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$143K - $176K *

Champion product marketing initiatives across diverse tools, guiding go-to-market strategies and collaborating with cross-functional teams to enhance user engagement and adoption, while driving measur...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$85K - $110K *

Build strong executive relationships and drive growth in strategic accounts while guiding clients with AI solutions and cloud technology in a fast-paced environment. Leverage your expertise to unlock...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Transform patient care as a Registered Pharmacist, ensuring accurate prescriptions, providing expert counseling, and driving community wellness initiatives while leading a dedicated pharmacy team...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Shape customer success by building strong partnerships, managing accounts, and translating data into actionable insights. Drive advocacy and operational efficiency while collaborating cross-functional...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$268K - $282K *

Shape the future of media products by driving strategy and innovation. Collaborate with cross-functional teams to enhance measurement and optimization capabilities, ensuring impactful solutions for cl...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $155K *

Join us to lead security and compliance initiatives within a dynamic platform team. You'll leverage your expertise to enhance production infrastructure, ensuring robust protection and reliability for...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.