Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$110K - $140K *

Join a dynamic team as you drive sales in the public safety sector, managing a diverse territory. Leverage AI tools to identify opportunities, close deals, and build lasting relationships with agencie...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$100K - $120K *

Accelerate client success by owning the onboarding and rollout for enterprise clients, ensuring smooth transitions from purchase to sustained usage. Collaborate with cross-functional teams to drive ad...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$135K - $160K *

Lead the strategy for the Commitments product, enhancing customer compliance tracking through AI. Collaborate with cross-functional teams to drive adoption and deliver impactful solutions that address...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $200K *

Lead the charge in driving membership growth through proactive prospecting and face-to-face sales. Engage small business owners, deliver compelling presentations, and overcome objections to achieve sa...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$80K - $200K *

Unlock potential by driving membership growth through face-to-face sales, prospecting, and relationship-building with small business owners. This dynamic role emphasizes direct engagement and achievin...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$135K - $160K *

Transform healthcare technology by owning core products, driving architectural decisions, and ensuring high-quality code. Collaborate across teams to deliver impactful solutions that enhance patient c...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Contribute to the evolution of US indirect tax compliance by analyzing multistate tax matters, streamlining processes, and collaborating with cross-functional teams to enhance accuracy and efficiency...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$63K - $111K *

Transform your career by joining a dynamic team as a Security Technician, where you'll travel to install, troubleshoot, and maintain advanced electronic systems, ensuring operational excellence across...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$80K - $95K *

Drive procurement excellence by managing supplier relationships and optimizing processes. Take ownership of sourcing strategies, ensuring compliance and cost savings while mentoring team members in a...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$125K - $150K *

Empower healthcare practices by serving as a strategic advisor, enhancing financial performance and operational strategies. Lead client relationships and support growth initiatives in a dynamic, entre...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$230K - $290K *

Drive the architecture and strategy for a high-volume telemetry platform, mentoring a team while collaborating across functions to enhance observability practices and ensure system reliability at scal...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$152K - $190K *

Join a team that's transforming industries through IoT solutions, driving impactful sales from prospecting to closing. Engage with executives, build lasting relationships, and thrive in a high-perform...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Lead the charge in enhancing engineering security for our SaaS platform. Collaborate with teams to identify risks, improve practices, and implement automation, ensuring secure development and robust v...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$144K - $209K *

Drive innovation by building scalable software solutions in a dynamic environment. Collaborate across teams to enhance user experiences and tackle complex challenges while leveraging cutting-edge tech...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$210K - $250K *

Empower a dynamic team of reimbursement professionals to enhance provider access and education. Drive strategic initiatives, foster collaboration, and ensure compliance while navigating complex payer...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$105K - $120K *

Help us drive sales growth and enhance community partnerships by leading a dynamic sales team focused on expanding market share and improving patient registrations in the healthcare sector...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$144K - $180K *

Lead the charge in managing daily operations, optimizing asset performance, and driving strategic initiatives. Collaborate across departments to enhance workforce effectiveness and ensure compliance w...

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$85K - $100K *

Join us to lead nursing practice across ambulatory and inpatient areas, enhancing patient care through education, consultation, and research. Collaborate with clinical leaders to improve orthopedic ca...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$104K - $194K *

Transform your career by spearheading agency relationships and driving profitable Inland Marine solutions while managing a territory remotely, influencing business growth through strategic underwritin...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$155K - $197K *

Innovate as a Tech Lead, driving architectural evolution and engineering execution for a global web platform. Collaborate with cross-functional teams to enhance digital experiences through advanced AI...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$160K - $190K *

Unlock your potential as a key player in software development, leading projects from design to deployment. Collaborate with cross-functional teams to enhance applications, optimize performance, and dr...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$138K - $187K *

Lead cross-functional quality initiatives to enhance product health and compliance. Collaborate with diverse teams on regulatory submissions, quality assessments, and process improvements for late-sta...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Join a team that's redefining product marketing by crafting compelling narratives and lifecycle campaigns that drive customer engagement and platform adoption across diverse segments. Collaborate with...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$175K *

Champion enrollment growth by leading a high-performing team, optimizing processes, and enhancing the student experience. Collaborate cross-functionally to drive strategic initiatives and achieve meas...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Join a dynamic team to enhance application security across web apps, APIs, and cloud services. Collaborate with development squads to prioritize vulnerabilities and implement proactive remediation str...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.