Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$140K - $160K *

Drive high-volume technical recruitment efforts, focusing on specialized roles like Data Scientists and AI Engineers. Collaborate with hiring managers to build strong candidate pipelines and ensure an...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$62K - $103K *

Transform client security by designing and deploying Microsoft 365 solutions. Engage with stakeholders, lead technical discussions, and ensure robust security postures across hybrid and cloud environm...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$62K - $103K *

Join us to design and deploy Microsoft 365 security solutions, advising clients on best practices across hybrid and cloud environments. Leverage your expertise in Defender XDR, Entra ID, and Intune wh...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$62K - $103K *

Join a dynamic team to design and implement Microsoft 365 security solutions, leveraging your expertise in Defender XDR, Entra ID, and Intune. Engage with clients to enhance their security posture in...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$62K - $103K *

Unlock potential by designing and deploying Microsoft 365 security solutions. Collaborate with clients to enhance security posture through technical expertise in Defender XDR, Entra ID, Intune, and Pu...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$184K - $356K *

Unlock potential by developing innovative AI solutions and enhancing infrastructure capabilities. Collaborate with strategic partners to deliver hands-on technical support, ensuring optimal performanc...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$85K - $111K *

Lead cross-functional teams to design and implement resilient infrastructure solutions. Collaborate with diverse stakeholders to ensure timely delivery of high-quality systems, leveraging automation a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$135K - $145K *

Deliver seamless integration and Tier 3 support for secure mobile infrastructure. Collaborate with enterprise stakeholders to ensure compliance, performance, and customer satisfaction while managing c...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $220K *

Champion innovation in macOS development, driving core sensor features for endpoint protection. Collaborate with a dynamic team to enhance security capabilities, ensuring high performance and reliabil...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$155K *

Transform complex challenges into impactful software solutions. Collaborate with engineers, designers, and justice leaders to drive product strategy and execution, enhancing the criminal justice syste...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Take ownership of software engineering initiatives within established companies. Lead teams, modernize development processes, and enhance code quality while delivering impactful software solutions. Co...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$161K - $190K *

Join us to define and evolve the architecture of a cutting-edge digital platform, guiding engineering decisions and establishing shared services for scalable, secure, and reliable solutions that empow...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$85K - $115K *

Elevate healthcare education by developing evidence-based content for clinicians. Collaborate with experts to create innovative learning materials that address practice gaps and enhance professional s...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$135K - $160K *

Lead a dynamic team to transform AI strategies into impactful healthcare solutions. Oversee engineering execution, guide architecture, and ensure compliance while collaborating with cross-functional p...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $92K *

Help us design and implement innovative software solutions that meet business needs. Collaborate with cross-functional teams to deliver scalable, secure applications while staying current with emergin...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $110K *

Advance your career by conducting vital physical security evaluations across multiple data centers. Collaborate with teams to enhance security measures and protect critical infrastructure while engagi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Join a team that's redefining product marketing by driving impactful go-to-market strategies, enabling sales teams, and translating complex product features into clear customer value across diverse ma...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$240K - $330K *

Join a team that’s pioneering growth in revenue intelligence by driving new business opportunities in financial services and healthcare. Leverage your extensive sales expertise to build relationships...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$172K - $216K *

Help us drive growth in the utilities sector by leading a high-performing sales team. You'll shape strategies, build relationships, and coach sellers to excel in complex, multi-year deals, ensuring al...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$120K - $180K *

Unlock potential by leading full-cycle sales in the corrections sector, driving innovative drone solutions. Collaborate with diverse teams to build trust and pipeline, while navigating complex agency...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$110K - $130K *

Unlock potential by driving pipeline visibility and forecasting accuracy. Collaborate with Sales, Marketing, and Finance to enhance workflows and insights, ensuring clean data and effective GTM strate...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$149K - $202K *

Transform the HCP launch landscape by leading innovative marketing initiatives for a groundbreaking treatment in Sjögren's disease. Collaborate cross-functionally to engage healthcare professionals an...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock potential by leading cross-functional initiatives to enhance caregiver enrollment technology. Drive strategy, optimize user experiences, and leverage data analytics to achieve growth in a dynam...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $125K *

Join a team that's transforming HR and payroll solutions by engaging clients, conducting tailored demos, and bridging business needs with technical expertise to enhance workforce management and compli...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$124K - $198K *

Transform your career by owning and accelerating Unstructured data protection sales. Leverage your technical expertise to drive growth, engage stakeholders, and win competitive deals in a dynamic, quo...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.