Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$145K - $175K *

Lead commercial legal initiatives by providing strategic counsel, drafting agreements, and collaborating with cross-functional teams to drive business objectives while managing legal risks effectively...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$89K - $120K *

Shape the future of litigation support by managing subpoenas and discovery processes. Collaborate with attorneys and paralegals to ensure timely document production and case management while maintaini...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$73K - $99K *

Take ownership of financial oversight and reporting for private debt funds, collaborating with diverse teams to enhance fund accounting, investor reporting, and audits, while gaining insights into com...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Lead the charge in directing clinical rehabilitation operations across multiple practices, ensuring quality patient care and achieving financial and operational objectives through effective management...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Drive growth by owning the self-serve revenue engine, optimizing user experiences, and leading experimentation to boost conversions. Collaborate across teams to enhance product adoption and revenue, p...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$100K - $124K *

Optimize financial integrity by leading core accounting teams, ensuring accurate and timely financial closes, and driving continuous improvement initiatives while maintaining compliance with GAAP and...

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Champion growth by developing and executing territory plans to maximize revenue. Collaborate with sales, marketing, and business development teams to drive results and enhance market share through eff...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Transform your career by leading the legal function for a pioneering foundation. You'll navigate complex IP, AI regulation, and nonprofit governance, ensuring compliance while fostering innovation and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Lead the charge in transforming patient engagement by integrating booking into our core product. Drive innovative experiments and optimize multi-channel outreach to ensure underserved communities rece...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $143K *

Engage actively in assessing credit risk for commercial clients, ensuring compliance and sound lending practices while collaborating closely with relationship managers to facilitate decision-making an...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $145K *

Unlock potential by driving AI security marketing initiatives, creating demos, and collaborating with cross-functional teams to enhance product visibility and adoption. Serve as the technical voice fo...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$98K - $122K *

Empower progress at the intersection of project management and benefits innovation. Lead initiatives for 401(k) MEP and Benefits Billing, collaborating with diverse stakeholders to enhance operational...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$95K - $158K *

Transform the Property Intelligence platform by connecting customer needs with product insights. Collaborate across teams to enhance product adoption and engagement through analytics and feedback, dri...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$165K - $225K *

Unlock your potential by designing and operating robust Kubernetes infrastructure. Collaborate with cross-functional teams to ensure high-performance, reliable systems that support enterprise-scale AI...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Innovate demand generation strategies by managing paid media, automating workflows, and leveraging AI tools. Collaborate with teams to enhance pipeline efficiency and drive measurable results through...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Media

$200K - $230K *

Lead customer success initiatives by managing federal program delivery, ensuring seamless deployment, support, and renewal processes. Drive team performance and build strategic partnerships to enhance...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$130K - $160K *

Empower AI innovation by designing and building robust tooling for deploying AI agents in production. Collaborate with cross-functional teams to enhance infrastructure reliability and developer experi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$132K - $170K *

Shape the future of client relationships by driving retention and growth through strategic account management and consultative sales, engaging with C-level executives to maximize value and expand serv...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$150K - $180K *

Shape and execute a comprehensive partnership strategy to drive growth, enhance market presence, and foster high-value alliances across the healthcare ecosystem, collaborating with executive leadershi...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$80K - $95K *

Champion the Technical Solutions team by leading projects, enhancing quoting processes, and collaborating cross-functionally to ensure customer satisfaction and operational excellence while driving co...

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$110K - $130K *

Champion transformative initiatives by translating priorities into actionable plans, coordinating cross-functional teams, and driving organizational change to enhance operational effectiveness and ado...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $140K *

Lead the charge in driving sales for mid-sized public safety agencies, managing full-cycle deals from opportunity identification to closing. Collaborate with cross-functional teams to ensure successfu...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$106K - $167K *

Join us to analyze and optimize complex business processes, design ERP solutions, and lead integration efforts. Collaborate with teams to enhance performance and ensure compliance while delivering hig...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $190K *

Pioneer innovative AI solutions to transform biomedical discovery, collaborating with top scientists and engineers to bridge virtual and real-world data, enhancing drug discovery and clinical care pro...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Help us deliver exceptional training and support for medical imaging equipment, enhancing customer experiences through expertise and mentorship while traveling frequently to engage with healthcare pro...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.