Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$100K - $120K *

Transform patient care as a Floating Registered Pharmacist, delivering exceptional service across multiple locations. Collaborate with teams, counsel patients, and ensure compliance while thriving in...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Unlock potential by delivering exceptional patient care as a Registered Pharmacist. You'll fill prescriptions, counsel patients, and support wellness initiatives, all while collaborating with a dedica...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$78K - $113K *

Innovate healthcare fraud prevention by leading complex investigations, evaluating medical necessity, and collaborating with regulatory agencies to ensure quality member care and safeguard plan assets...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$78K - $113K *

Unlock potential by leading complex investigations into healthcare fraud, waste, and abuse. Collaborate with regulatory agencies and internal teams to ensure compliance and safeguard member care while...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $189K *

Transform SAP ABAP development for mission-critical DoD logistics systems, ensuring alignment with regulatory requirements and optimizing user interfaces while collaborating across teams to enhance op...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$105K - $231K *

Accelerate progress at the forefront of SAP integration, driving complex data exchanges and ensuring compliance with DoD standards while enhancing transportation operations across diverse systems...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$75K - $158K *

Drive agile excellence by coaching teams in a scaled framework, facilitating planning, and enhancing collaboration. Engage with stakeholders to ensure successful delivery and continuous improvement in...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $189K *

Shape the future of network infrastructure by leading modernization efforts across classified and unclassified systems. Collaborate with teams to design secure, high-performance networks while ensurin...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $158K *

Join us to lead agile teams in a dynamic environment, coaching and facilitating processes to enhance productivity and collaboration. Drive successful project delivery while fostering strong relationsh...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $189K *

Contribute to critical government missions as a Release Train Engineer, facilitating Agile Release Train events, coaching teams, and driving continuous improvement to deliver value using cutting-edge...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $158K *

Elevate your career as a Senior Business Systems Analyst, driving modernization initiatives in federal financial systems. Collaborate with teams to analyze data, implement solutions, and lead developm...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Transform the member experience by owning the full lifecycle of features across a cutting-edge AI-first platform, leveraging technologies from React to GraphQL and AI services to deliver personalized...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$100K - $120K *

Join a team that's driving growth in the commercial sector by leveraging data and AI solutions. As an Account Executive, you'll cultivate relationships, manage accounts, and optimize customer success...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$134K - $205K *

Drive civil and structural construction excellence by managing on-site activities, ensuring compliance with safety and quality standards, and collaborating with diverse teams to meet project milestone...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$160K - $180K *

Drive innovation as a Senior Product Manager, leading strategic initiatives in Adaptive Training and Continuous Learning. Collaborate with cross-functional teams to enhance user experiences and achiev...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $190K *

Lead project scheduling across a diverse portfolio, ensuring timely execution and risk mitigation. Collaborate with teams to develop critical path schedules, manage resources, and enhance project deli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$115K - $175K *

Lead the charge in ensuring mission-critical projects meet quality standards through effective commissioning strategies, technical oversight, and stakeholder coordination. Drive operational readiness...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$180K - $225K *

Join a team that's driving operational excellence in platform management. As a key leader, you'll enhance mission readiness, enforce standards, and integrate cross-functional teams to ensure seamless...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$120K - $155K *

Join a team that's dedicated to enhancing national security through expert program analysis. Leverage your extensive experience to support critical FAA initiatives, ensuring compliance and effective p...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$164K - $228K *

Transform complex systems into a cohesive architecture by leading end-to-end solutions across CRM, billing, and integrations. Collaborate with stakeholders to address challenges and drive modernizatio...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $150K *

Lead the charge in overseeing large-scale construction projects, ensuring fiscal success and client satisfaction. Collaborate with teams to manage budgets, schedules, and quality from pre-construction...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$95K - $115K *

Drive high-quality technical support for aviation connectivity systems, ensuring customer satisfaction through troubleshooting, training, and collaboration with cross-functional teams in a fast-paced...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$93K - $134K *

Drive impactful data mining initiatives by analyzing complex claims across Medicare, Medicaid, and Commercial sectors. Leverage your expertise to identify anomalies and enhance recovery opportunities...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$125K - $150K *

Optimize reimbursement strategies and regulatory compliance by leading analysis, developing policies, and mentoring teams. Drive operational excellence and foster relationships with stakeholders to en...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Unlock potential by leading technical vision and mentoring engineers. Drive modernization and collaboration across teams to build resilient, scalable infrastructure while fostering a high-performance...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.