Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$98K - $130K *

Drive financial excellence by leading cost accounting operations, ensuring accurate reporting and analysis. Collaborate across departments to support strategic business decisions and contribute to tim...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$195K - $264K *

Drive global regulatory strategies for obesity and cardiometabolic disorders, ensuring alignment across teams and leading interactions with health authorities. Leverage scientific expertise to navigat...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$217K - $294K *

Innovate the U.S. Cardiovascular & Metabolic Medical strategy, leading evidence generation and stakeholder engagement for chronic weight management. Collaborate cross-functionally to ensure launch rea...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $135K *

Elevate our proposal management efforts by leading strategic submissions, fostering collaboration among teams, and enhancing our pursuit capabilities to secure high-value projects that improve infrast...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Technical Services

$86K - $138K *

Lead the charge in defining and executing a comprehensive product strategy, driving value across product portfolios. Collaborate with key stakeholders to align strategic vision while overseeing perfor...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in delivering complex renewable energy projects, ensuring safety, quality, and budget adherence. Collaborate with diverse stakeholders to drive project success from development through...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$90K - $100K *

Join a team that's driving franchise sales success by leading, coaching, and developing a high-performing sales team. Optimize processes, leverage analytics, and collaborate across departments to enha...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$80K - $95K *

Elevate your career as a Senior Accountant, driving day-to-day operations and enhancing internal processes. Collaborate with teams to transition activities, ensuring accuracy and scalability in a fast...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$115K - $120K *

Innovate solutions for time capture and billing in a dynamic team. Leverage AI tools to enhance software development, ensuring accuracy and efficiency in invoicing processes while collaborating across...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$74K - $91K *

Contribute to national health data collection efforts by leveraging your nursing expertise and survey research skills. Engage in participant-centered data collection, quality control, and training whi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$119K - $221K *

Advance your career by driving strategic sales initiatives within large enterprises. Collaborate with cross-functional teams to exceed sales quotas and develop innovative solutions that meet client ne...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$75K - $88K *

Join a team that's dedicated to maintaining and enhancing electrical systems. This role involves skilled installation, repair, and inspection of control systems, ensuring operational efficiency and sa...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$140K - $170K *

Join us to drive growth in the travel loyalty sector by building relationships with airlines, hotels, and gaming operators. You'll lead new business initiatives, shaping partnerships that enhance cust...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$160K - $200K *

Lead the charge in providing tailored financial planning and investment strategies for senior executives. Collaborate with a dedicated team to enhance client relationships and drive business growth wh...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$130K - $163K *

Champion the analytical validation of NGS assays, driving real-world evidence studies and collaborating with cross-functional teams to enhance oncology applications and support regulatory submissions...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead the charge in driving sales performance by building relationships with healthcare professionals and executing strategic territory plans to achieve business objectives and market share growth...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $215K *

Lead the charge in driving strategic growth and client satisfaction by managing senior-level relationships, leveraging cross-functional resources, and delivering measurable business value within a por...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Champion the clinician experience by designing and optimizing tools that enhance daily workflows, ensuring seamless integration of clinical data and improving patient care delivery in home settings...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Shape the future of networking by designing and implementing advanced SDN orchestration systems for high-performance, isolated networking in distributed computing environments, enabling seamless acces...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$183K - $301K *

Accelerate growth by leading strategic partnerships and go-to-market initiatives in the healthcare ecosystem. Drive revenue through collaboration, executive influence, and innovative business models w...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $159K *

Inspire excellence in clinical documentation by leading a team of specialists, ensuring quality assurance, and fostering professional development. Collaborate with stakeholders to enhance operational...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $150K *

Champion a high-impact sales experience, driving customer engagement and loyalty. Own the sales cycle from initial contact to follow-up, consistently exceeding goals while benefiting from a supportive...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$175K - $200K *

Join a team that's dedicated to overseeing compliance and security initiatives, including FedRAMP and SOC audits. Collaborate across departments to enhance data protection and drive organizational suc...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Drive excellence in equipment reliability and maintenance across multiple facilities. Collaborate with teams to enhance safety, implement best practices, and manage capital projects, ensuring optimal...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$113K - $254K *

Drive innovation by developing scalable Python services and AI-driven solutions. Collaborate with data science teams to enhance pricing automation and improve operational efficiency in a fully remote...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.