Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,075

Sort By: Relevance

$162K - $195K *

Drive sales performance by launching a novel cardiac myosin inhibitor, building strategic relationships with healthcare providers, and coordinating a local integrated field team to meet patient needs...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$75K - $123K *

Join a team that's dedicated to enhancing Payment Integrity Audit programs by collaborating with stakeholders, managing inventory, and driving process improvements in a fast-paced environment focused...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$85K - $110K *

Elevate quality assurance in clinical DRG audits by mentoring auditors, ensuring accuracy, and recommending process improvements. Collaborate with peers to enhance performance and uphold compliance st...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$93K - $163K *

Drive effective marketing strategies for cybersecurity offerings, collaborating with cross-functional teams to enhance product management and deliver impactful go-to-market initiatives, while ensuring...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$73K - $101K *

Unlock potential by leading installation, maintenance, and repair of low voltage power distribution systems. Collaborate with teams to ensure safety and efficiency while delivering exceptional service...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Transform enterprise modernization by leading user-centered design and business analysis initiatives. Collaborate with stakeholders to optimize workflows, enhance user experiences, and drive strategic...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$175K - $237K *

Empower your leadership skills by overseeing county operations, managing budgets, and driving strategic initiatives. Collaborate with diverse teams to enhance service delivery and ensure effective gov...

Today

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Lead the charge in enhancing complex Federal applications by designing, developing, and maintaining full-stack solutions using Java and Angular. Collaborate in an Agile environment to deliver secure...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Elevate your career by driving sales in the employer benefits space. Shape growth, manage relationships, and collaborate across teams to deliver impactful solutions for SMB clients in the Rocky Mounta...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Hospitality & Recreation

$85K - $90K *

Unlock potential by leading a dynamic Customer Success team to enhance client satisfaction, drive product adoption, and identify upselling opportunities, ensuring customers achieve their business goal...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $105K *

Champion dealership sales performance by collaborating with management to enhance digital strategies, optimize processes, and drive effective communication, ensuring maximum impact on sales outcomes a...

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$125K *

Empower your sales career by driving growth in the SaaS/Security sector. Build relationships with key decision-makers, exceed quotas, and collaborate across teams to deliver exceptional value and solu...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$112K - $140K *

Transform the future of software development by architecting and enhancing back-end solutions across diverse applications, mentoring engineers, and driving Agile processes to deliver high-quality soft...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Transform your career by leading new business acquisition in a dynamic sales environment. Engage with key stakeholders to drive large-scale security and compliance solutions, leveraging your expertise...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$75K - $95K *

Join a team that's dedicated to delivering impactful user events across North America and Europe. You'll manage logistics, coordinate teams, and ensure engaging experiences that drive product adoption...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$200K - $232K *

Lead the charge in shaping innovative educational products for universities, enhancing faculty engagement and institutional adoption through AI-driven solutions and comprehensive support, while drivin...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$108K - $155K *

Elevate your career by leading complex public sector deployments, ensuring seamless execution of Zero Trust solutions while collaborating with cross-functional teams to achieve impactful business outc...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Transform core GRC platform capabilities into intelligent, agentic experiences. Own the product strategy, engage with stakeholders, and redefine user workflows while enhancing automation and flexibili...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$9K - $185K *

Lead the optimization of large-scale SQL Server databases, enhancing performance and efficiency. Drive data mining capabilities by resolving bottlenecks and implementing innovative solutions that dire...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Help us shape the future of partner marketing by crafting compelling narratives that drive adoption and engagement for our Buyer Intent product line, collaborating with cross-functional teams to deliv...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Unlock new business opportunities by driving sales growth in emerging healthcare markets. This role focuses on building relationships with non-national health plans and technology partners, achieving...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$88K *

Advance the prosecution of criminal cases in Woodbury County, ensuring justice through effective legal representation, case preparation, and courtroom advocacy while collaborating with law enforcement...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Unlock potential by leading strategic provider network contracting initiatives, driving negotiations, and fostering collaboration across departments to enhance healthcare quality, affordability, and s...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$106K - $177K *

Shape customer success by managing enterprise accounts, driving satisfaction and retention through strategic guidance, proactive support, and relationship building. Collaborate with sales teams to max...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Transform customer success at a strategic level by leading a diverse team of CSMs, driving initiatives to enhance satisfaction, retention, and growth while collaborating across departments to align wi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.