Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,075

Sort By: Relevance

$72K - $116K *

Join a dedicated team to provide comprehensive case management services, ensuring quality care delivery and optimal health outcomes for members. Assess needs, develop care plans, and coordinate servic...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$140K - $180K *

Shape the future of clinical quality assurance by overseeing trials, ensuring compliance with GCP and ICH standards, and driving operational excellence across clinical activities within a cross-functi...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$115K - $140K *

Elevate your career by managing day-to-day accounting operations, ensuring compliance with U.S. GAAP, and collaborating across departments to support financial reporting and audits in a dynamic pharma...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Unlock potential by driving sales in the employer benefits space, managing relationships, and closing deals in Texas and Oklahoma. Collaborate with teams to shape growth and ensure successful implemen...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Hospitality & Recreation

$115K - $145K *

Advance your career by managing district relationships and ensuring exceptional service delivery. Collaborate with operations to resolve issues, present performance metrics, and drive customer satisfa...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Transportation

$110K - $130K *

Drive your career with a dynamic role in Identity DevOps, focusing on IAM solutions, SSO integrations, and production support. Collaborate across teams to enhance security and user experience while ma...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$105K - $231K *

Shape the future of AI/ML by designing innovative computer vision solutions. Collaborate with cross-functional teams to deliver impactful software applications while leveraging cutting-edge technologi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Empower clients by delivering exceptional support and insights in Managed Security Solutions. Drive client satisfaction through effective onboarding, technical discussions, and relationship management...

Today

  •   Less than 5 years exp.  •   Information Technology

$95K - $105K *

Drive your career with a key role in supporting retrofit sales through strategic technical field support, optimizing HVAC systems, and enhancing customer engagement across a regional territory...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$130K - $165K *

Drive strategic growth by acquiring new logos and expanding partnerships within large health systems. Navigate complex sales cycles, build executive relationships, and enhance enterprise value through...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$88K - $105K *

Transform manufacturing processes by leading R&D Technical Services, ensuring safe and efficient operations while driving innovation and continuous improvement across cross-functional teams in a dynam...

Today

  •   5 - 7 years exp.  •   Food & Beverages

$80K - $95K *

Join a team that's dedicated to excellence in marine engineering, supervising vessel maintenance and leading projects to ensure fleet reliability while developing specifications and solutions that enh...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Transportation

$70K - $95K *

Unlock potential by leveraging data insights to drive scalable growth and enhance sales team performance. Collaborate with leadership to develop strategies that improve productivity and operational ef...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Transportation

$85K - $95K *

Empower your career as a Senior Business Intelligence Analyst, modernizing data extraction and automation. Collaborate across teams to deliver actionable insights using AI and BI tools, ensuring clari...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Media

$80K - $95K *

Lead the charge in designing immersive environments that enhance brand experiences. Drive innovation and collaboration across teams to execute high-visibility projects, influencing showroom strategies...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$86K - $165K *

Transform the future of avionics by designing cutting-edge circuit cards for mission-critical systems. Collaborate with cross-functional teams to ensure compliance and performance throughout the hardw...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$120K - $145K *

Transform complex security architectures into compelling business narratives that resonate with enterprise decision-makers. Collaborate across teams to drive product positioning, messaging, and go-to...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$102K - $123K *

Join us to lead complex client programs, coordinating cross-functional teams and ensuring seamless delivery of diverse learning solutions. Utilize your expertise to enhance operational processes and f...

Reposted today

  •   Less than 5 years exp.  •   Business Services

$150K - $357K *

Drive impactful SAP Finance Transformation projects, collaborating with clients to innovate and implement solutions that enhance business value. Lead diverse teams and navigate complex challenges in a...

Today

  •   11 - 15 years exp.  •   Business Services

$115K - $125K *

Drive client satisfaction and retention by managing complex service plans, overseeing account strategies, and leading a dedicated team to enhance revenue growth and address customer needs effectively...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$108K - $125K *

Champion innovative solutions as a Full Stack Engineer, delivering impactful features and enhancing systems across projects. Collaborate, design, and optimize applications with a focus on performance...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$130K - $140K *

Lead the charge in delivering enterprise data platform initiatives, managing Agile processes, and ensuring effective collaboration across teams. Drive project execution from discovery to deployment wh...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$122K - $175K *

Unlock potential by leading the design and maintenance of scalable cloud infrastructure. Drive innovation in cloud technologies, ensuring robust security and efficient deployment while collaborating w...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$175K - $243K *

Engage with enterprise merchants to architect scalable solutions, leveraging technical expertise and collaboration across teams. Drive pre-sale activities, build trust, and influence product developme...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Finance & Insurance

$191K - $260K *

Drive ERP strategy and modernization initiatives, collaborating with leaders to ensure technology investments yield significant business value and enhance operational efficiency across the organizatio...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.