Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$215K - $250K *

Build your career with a pioneering role to shape grantmaking, partner programs, and organizational independence. Lead initiatives, engage stakeholders, and measure success while establishing a founda...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $200K *

Transform your career by leading key client relationships, understanding business goals, and driving innovative manufacturing solutions to market. Leverage your expertise to boost sales and collaborat...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$63K - $98K *

Lead the charge in ensuring seamless onboarding for new customers, coordinating efforts across teams to deliver a professional transition from sales to support, while fostering strong relationships an...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$75K - $125K *

Empower growth by driving strategic account management and sales initiatives. Collaborate with diverse teams to deliver innovative manufacturing solutions, ensuring client success and exceeding revenu...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$164K - $241K *

Lead a global TPRM program, enhancing vendor security risk management through AI-driven workflows and assessments. Manage a team, ensure compliance, and drive risk decisions while collaborating with c...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$86K - $138K *

Optimize financial analysis and reporting by conducting in-depth research, preparing forecasts, and collaborating across departments to enhance business outcomes and drive strategic decision-making...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $110K *

Join us to drive cross-functional GTM initiatives, enhance operational efficiency, and support executive decision-making. You'll collaborate with teams to align strategies and improve processes, ensur...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$128K - $191K *

Join a team that's driving growth in the CBRNe Safety & Security sector. You'll identify new business opportunities, develop strategies, and manage the sales cycle while collaborating with cross-funct...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$104K *

Champion legal excellence by representing the County in complex criminal, juvenile, and civil cases. Collaborate with officials, mentor junior attorneys, and provide strategic legal counsel while ensu...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$135K - $160K *

Elevate your career by leading strategic initiatives that drive provider growth. Collaborate with C-suite leaders to design scalable operations and align cross-functional teams, while mentoring a dedi...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Healthcare

$92K - $115K *

Unlock your potential by providing holistic patient care across diverse settings. Collaborate with a dedicated team to enhance health outcomes for underserved populations while navigating evolving hea...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Champion innovative research in clinical assessments, leading product development and strategy across multiple domains. Collaborate with cross-functional teams to translate scientific evidence into im...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$280K - $330K *

Empower a dynamic engineering team by leading technical architecture, enhancing system reliability, and driving scalable solutions that support rapid growth in a fast-paced fintech environment. Foster...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$160K - $180K *

Drive growth and satisfaction by managing client relationships in Life Sciences. Oversee the sales process, collaborate with experts, and leverage insights to uncover new opportunities while ensuring...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$155K - $170K *

Transform the national media landscape by leading strategic communications initiatives that elevate awareness of Alzheimer’s disease and dementia. Collaborate with executive leadership to drive impact...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$135K - $160K *

Lead the development of AI-driven systems for onboarding and compliance, enhancing customer journeys for major financial institutions. Collaborate with cross-functional teams to optimize processes and...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$106K - $284K *

Elevate your career by leading a dynamic engineering team to build scalable, cloud-native solutions within the Salesforce ecosystem, driving innovation across key business areas like Marketing, Sales...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the charge in optimizing our rendering system, enhancing performance and user experience across cutting-edge video technologies. Collaborate with a dynamic team to push the boundaries of audio an...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$116K - $171K *

Join a team that's dedicated to delivering exceptional technical support to strategic customers. Leverage your expertise to resolve complex issues, enhance customer experiences, and drive improvements...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Transportation

$153K - $226K *

Advance your career by owning and evolving our Workday platform, focusing on payroll and Core HCM. Collaborate with cross-functional teams to design scalable systems that enhance operational efficienc...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Lead engineering initiatives by developing customer relationships and delivering tailored solutions. Oversee team performance, manage workloads, and ensure engineering excellence while driving busines...

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Drive impactful data science initiatives by leading a high-performing team, fostering collaboration, and ensuring effective delivery of analytics solutions that create measurable business value and pr...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$145K - $193K *

Architect and enhance robust software solutions for player registration, identity verification, and compliance. Collaborate across teams to optimize performance, scalability, and security while mentor...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$140K - $185K *

Inspire the evolution of a brand by leading innovative design for campaigns and web experiences. Collaborate across teams to develop scalable brand systems, mentor creatives, and direct impactful stor...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$87K - $110K *

Unlock your potential as you lead innovative research projects, collaborate with diverse teams, and drive data-driven solutions that enhance opportunities and improve lives across various policy areas...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.