Welcome to Information Systems Security Officer (ISSO) Jobs

As an Information Systems Security Officer (ISSO), you play a critical role in protecting an organization's information system. Discover opportunities that pay over $100k, exclusively available on Ladders.

Job responsibilities

As an ISSO, your responsibilities can include ensuring system security, conducting regular checks, and implementing the organization's security policy.

Skills Needed

Successful ISSOs often have strong technical abilities, knowledge of IT security, problem-solving skills, and an understanding of relevant laws and regulations.

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$120K - $180K *

Lead the design and operation of agentic AI systems to enhance consulting and internal operations. Own production AI tooling from stakeholder requests to deployment, ensuring a seamless user experienc...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $135K *

Transform business needs into scalable ServiceNow solutions by leveraging technical expertise and collaboration with stakeholders. This role blends product ownership with development to drive successf...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$200K - $220K *

Unlock potential by driving growth strategies in Federal ground-based logistics. Manage complex pursuits, develop customer relationships, and lead capture efforts to secure high-value contracts, foste...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Transportation

$94K - $116K *

Unlock potential by leading analytical strategies that drive insights and performance across diverse data sets in healthcare. Collaborate cross-functionally to enhance operations, support business dec...

US-AnywhereRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$71K - $119K *

Drive the installation and maintenance of marine propulsion systems while ensuring technical excellence in complex environments. Engage directly with customers and lead diverse teams across various sh...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$198K - $273K *

Join a team that's shaping the future of partner-led security practices. In this senior role, you'll guide strategic partners in building technical capabilities and services, driving sustained growth...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$133K - $173K *

Unlock your potential as you lead outsourcing strategies for pharmacovigilance operations, managing a multi-million-dollar budget while fostering innovative solutions in a dynamic remote environment...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$74K - $111K *

Transform data into actionable insights and strategies by partnering closely with product teams, leveraging analytics and statistical techniques to enhance product decisions and drive innovation acros...

US-AnywhereRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Shape the environmental, health, and safety strategy for large-scale data center operations, ensuring safety and compliance throughout all phases—from design to ongoing operations—while collaborating...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$80K - $95K *

Serve as a trusted advisor, improving client operations through expert guidance and technical support on proprietary software. Drive customer success and foster relationships while partnering with sal...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$90K - $110K *

Lead and optimize order fulfillment processes by managing customer transactions, coordinating provisioning activities, and ensuring service level agreements are met while fostering stakeholder communi...

US-AnywhereRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Technical Services

$175K *

Empower clinical research excellence by leading rater training and endpoint surveillance initiatives to enhance the scientific integrity of trials while promoting evidence-based methodologies and coll...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$179K - $251K *

Lead the charge in shaping the Sales Engineering team for the US Public Sector, driving technical excellence and strategic growth while supporting key government accounts in cybersecurity and threat i...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$85K - $95K *

Transform procurement operations by leveraging Coupa software to enhance efficiency, manage vendor relationships, and ensure compliance in strategic sourcing and accounts payable processes...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$143K - $214K *

Advance your career by driving enterprise sales for an innovative AI security platform. Engage with senior stakeholders to deliver tailored solutions, ensuring the secure adoption of Generative AI in...

US-AnywhereRemote

1 month ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Engage with us to craft cutting-edge design systems that enhance healthcare software through collaboration and innovation. Drive consistency and accessibility as you build robust component libraries f...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $170K *

Drive innovative underwriting solutions for complex specialty accounts while managing relationships and strategic growth initiatives that enhance profitability within your territory...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$148K - $274K *

Lead strategic compliance initiatives for health plans, ensuring adherence to regulatory requirements while fostering cross-functional collaboration. Drive improvements in compliance programs and main...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$148K - $266K *

Transform your career by leading strategic operations and governance in risk and security. Serve as a key partner to executives, driving enterprise strategy and delivering measurable value through eff...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$70K - $95K *

Transform healthcare engagement by enhancing our social media presence, driving community interactions, and shaping brand perception across multiple platforms while collaborating cross-functionally to...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$151K - $226K *

Elevate your career by conducting impactful analyses on Real-World Data (RWD) for vital RWE studies. Collaborate with experts to produce rigorous, high-quality results that inform healthcare decisions...

US-AnywhereRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $140K *

Contribute to seamless technical integrations by assessing partner systems, guiding implementations, and troubleshooting issues. Build trust with partners and internal teams while enhancing customer e...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $145K *

Empower and lead a dynamic team of consultants, driving superior client satisfaction through effective program management and operational excellence in a fast-paced cybersecurity compliance environmen...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Lead the charge in managing regulatory submissions, ensuring alignment with global strategies and local requirements. Collaborate across teams to achieve timely site activations and maintain complianc...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Shape post-sales success for federal customers by driving adoption and measurable value through proactive engagement. Collaborate with internal teams to enhance outcomes and promote best practices to...

US-AnywhereRemote

4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What is the role of an Information Systems Security Officer (ISSO)?question toggle

    An ISSO is responsible for ensuring the confidentiality and integrity of an organization's information system. They implement the organization's IT security policies and conduct regular checks and audits.

  • What skills do you need for ISSO jobs?question toggle

    ISSOs need strong technical abilities, knowledge of IT security, problem-solving skills, and an understanding of relevant laws and regulations.

  • What kind of ISSO jobs are available on Ladders?question toggle

    Ladders offers a variety of high-paying ISSO jobs from reputable companies that value your skills and experience.