Information Systems Security Officer (ISSO) Jobs

Information Systems Security Officers help organizations protect sensitive data, systems, and networks. ISSOs assess security risks, guide teams through compliance requirements, and help ensure that information systems are designed and operated securely. Explore vetted ISSO opportunities on Ladders, including professional roles that pay $100,000 or more.

What Does an ISSO Do?

Responsibilities vary by employer and industry, but ISSOs commonly maintain security documentation, monitor system controls, coordinate risk assessments, and support authorization and compliance activities. They may work with system owners, security engineers, auditors, and government stakeholders to identify vulnerabilities and address findings.

Common ISSO Skills and Qualifications

Employers often seek experience in information security, risk management, security controls, and regulatory or government frameworks. Familiarity with standards such as NIST guidance, authorization processes, incident response, and security assessment practices can be valuable. Some roles require a bachelor’s degree, relevant certifications, security clearance, or experience supporting federal systems; requirements differ by position.

ISSO Career Opportunities

ISSO professionals work across government contracting, defense, technology, healthcare, financial services, and other sectors with complex security needs. Depending on experience, they may advance into senior ISSO, information assurance, cybersecurity program management, or security leadership roles. Browse current listings to compare responsibilities, qualifications, work arrangements, and compensation.

Find ISSO Jobs on Ladders

Use Ladders to explore vetted professional opportunities, including Information Systems Security Officer jobs with salaries of $100,000 or more. Review each listing for its specific pay range, location, clearance requirements, and experience expectations, then apply to roles aligned with your background.

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$90K - $189K *

Drive the transformation of federal HR systems by leading the functional design of Oracle Fusion Cloud HCM modules, collaborating with stakeholders to deliver modern, efficient solutions for millions...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$94K - $157K *

Unlock potential by designing and delivering innovative RPA solutions using UiPath. Collaborate with cross-functional teams to enhance automation processes, ensuring high-quality outcomes and adherenc...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

$94K - $157K *

Engineer and deliver innovative RPA solutions using UiPath, collaborating across teams to meet organizational needs. This role requires hands-on expertise, commitment to quality, and participation in...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Join a team that's redefining enterprise cybersecurity sales, driving growth through innovative AI solutions. You'll engage with key stakeholders, own the sales cycle, and shape strategies for large e...

Dallas, TXRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$94K - $145K *

Lead the charge in optimizing Microsoft 365 operations, ensuring seamless administration and management of tenant subscriptions, Exchange online, and identity services while leveraging best practices...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$75K - $158K *

Champion the Alteryx platform by ensuring secure, efficient operations and integration across enterprise analytics. Collaborate with cross-functional teams to enhance data-driven decision-making and a...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $178K *

Transform data governance by leading initiatives that bridge legal compliance, data security, and technology operations. Drive innovative self-service workflows while ensuring compliance across divers...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$175K - $200K *

Elevate client security practices by architecting advanced SOC solutions, enhancing threat detection and exposure management capabilities. Lead high-impact engagements, translating complex security ne...

Dallas, TXRemote

4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$83K - $125K *

Drive the operational health of mission-critical Appian environments, ensuring reliability and performance. Collaborate with cross-functional teams to manage configurations, deployments, and incident...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$140K - $228K *

Lead the charge in enhancing cybersecurity by driving detection engineering, incident response, and automation. Collaborate cross-functionally to secure cloud architectures and improve operational eff...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$135K - $150K *

Champion innovation by enhancing our cloud infrastructure and automating operations. Collaborate with cross-functional teams to drive AI-powered solutions and ensure software reliability in a dynamic...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$175K - $251K *

Lead the charge in transforming customer experiences through innovative cloud security solutions, leveraging your expertise to craft tailored technical presentations and solutions that drive strategic...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$65K - $123K *

Join a team that's dedicated to providing expert DB2 support for mainframe clients. You'll manage database upgrades, maintenance, and performance tuning while ensuring timely solutions to enhance cust...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$99K - $159K *

Unlock the potential of AI in IT service management by implementing and optimizing ServiceNow tools. Collaborate with cross-functional teams to enhance knowledge management and ultimately deliver outs...

Norfolk, VARemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Transform complex cloud and data center solutions by leading implementations, ensuring technical readiness, and delivering exceptional customer support throughout the project lifecycle. Drive innovati...

Savannah, GARemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$129K - $175K *

Champion the optimization of mission-critical Oracle EBS environments, ensuring seamless database administration and support for complex financial systems. Collaborate with cross-functional teams to e...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$135K - $216K *

Shape the future of aviation by ensuring the highest quality standards in site installations for critical FAA systems. This hands-on role requires expertise in construction inspection and quality assu...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$100K - $130K *

Drive your career forward by leading federal proposal efforts from start to finish. Collaborate with cross-functional teams to create compelling, compliant proposals for defense and civilian sectors...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $158K *

Shape the future of federal data integration by leveraging Oracle EBS expertise to create actionable insights and advanced dashboards. Collaborate with cross-functional teams and enhance government da...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $94K *

Unlock potential by joining a dynamic team that supports military transitions into civilian roles. Gain hands-on experience in IT project management while collaborating with industry leaders to enhanc...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $130K *

Lead the charge in developing cloud strategies and governance frameworks for the Judiciary. Collaborate with stakeholders to enhance cloud adoption and ensure effective decision-making through compreh...

Virginia, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$89K - $148K *

Partner with us to design and implement secure architectures for enterprise environments, ensuring compliance with regulatory frameworks and cybersecurity best practices through expert collaboration a...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$105K - $170K *

Unlock exceptional communication and cybersecurity support as you bridge technical incident response with customer engagement, ensuring proactive guidance and clarity during active incidents for an ou...

California, USRemote

Reposted today

  •   Less than 5 years exp.  •   Enterprise Technology

$94K - $118K *

Unlock potential by driving application security initiatives through innovative tooling and automation. Collaborate closely with engineering teams to safeguard cloud platforms and implement security b...

CanadaRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $110K *

Lead the charge in conducting rigorous audits for compliance with international quality standards in high-consequence industries, ensuring operational effectiveness and safety through strategic planni...

Denver, CORemote

1 week ago

  •   5 - 7 years exp.  •   Staffing

Frequently Asked Questions (FAQ)

  • What is an Information Systems Security Officer (ISSO)?question toggle

    An ISSO is a cybersecurity professional who helps protect an organization’s information systems by coordinating security controls, assessing risks, maintaining documentation, and supporting compliance and authorization activities.

  • What qualifications are commonly required for ISSO jobs?question toggle

    Requirements vary, but employers commonly look for information security or IT experience, knowledge of security controls and risk management, and familiarity with relevant standards such as NIST guidance. Some positions may require a degree, professional certifications, or an active security clearance.

  • How much do Information Systems Security Officers earn?question toggle

    Compensation varies by employer, location, experience, clearance, and job scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check each listing for its stated salary or compensation details.

  • Where do ISSOs work?question toggle

    ISSO roles are found in government and defense contracting, technology, healthcare, financial services, and other industries that manage sensitive or regulated information.

  • How can I find ISSO jobs paying $100,000 or more?question toggle

    Browse Information Systems Security Officer listings on Ladders and review each posting’s compensation, qualifications, location, and clearance requirements to find roles that fit your experience.