Information Systems Security Officers help organizations protect sensitive data, systems, and networks. ISSOs assess security risks, guide teams through compliance requirements, and help ensure that information systems are designed and operated securely. Explore vetted ISSO opportunities on Ladders, including professional roles that pay $100,000 or more.
Responsibilities vary by employer and industry, but ISSOs commonly maintain security documentation, monitor system controls, coordinate risk assessments, and support authorization and compliance activities. They may work with system owners, security engineers, auditors, and government stakeholders to identify vulnerabilities and address findings.
Employers often seek experience in information security, risk management, security controls, and regulatory or government frameworks. Familiarity with standards such as NIST guidance, authorization processes, incident response, and security assessment practices can be valuable. Some roles require a bachelor’s degree, relevant certifications, security clearance, or experience supporting federal systems; requirements differ by position.
ISSO professionals work across government contracting, defense, technology, healthcare, financial services, and other sectors with complex security needs. Depending on experience, they may advance into senior ISSO, information assurance, cybersecurity program management, or security leadership roles. Browse current listings to compare responsibilities, qualifications, work arrangements, and compensation.
Use Ladders to explore vetted professional opportunities, including Information Systems Security Officer jobs with salaries of $100,000 or more. Review each listing for its specific pay range, location, clearance requirements, and experience expectations, then apply to roles aligned with your background.
Technical Delivery Manager - Healthcare, Release Management & AI
$120K - $145K *
Shape the future of patient services by ensuring timely delivery of features and integrations. Collaborate across teams to enhance operational efficiency in a compliance-heavy environment, driving inn...
4 days ago
$80K - $90K *
Analyze and deliver data management solutions to support public health research, utilizing advanced statistical software and collaborating with project leaders to enhance data quality and reporting fo...
2 weeks ago
$110K - $130K *
Shape the future of messaging systems by managing IBM MQ clusters, automating tasks, and ensuring optimal performance. Collaborate with teams to enhance file transfer solutions and troubleshoot comple...
2 weeks ago
$75K - $158K *
Join a dynamic team to develop RPA solutions using UiPath and Java technologies. Engage with stakeholders to implement automation solutions that enhance workflows while working on cutting-edge project...
Reposted 1 week ago
$150K - $160K *
Drive project success by managing integrated delivery across AI task orders, overseeing multidisciplinary teams, and ensuring adherence to quality standards while maintaining project roadmaps and sche...
2 weeks ago
Oracle Fusion Cloud HCM Functional
$90K - $189K *
Drive the transformation of federal HR systems by leading the functional design of Oracle Fusion Cloud HCM modules, collaborating with stakeholders to deliver modern, efficient solutions for millions...
Reposted 1 week ago
$94K - $157K *
Unlock potential by designing and delivering innovative RPA solutions using UiPath. Collaborate with cross-functional teams to enhance automation processes, ensuring high-quality outcomes and adherenc...
Reposted 2 days ago
Enterprise Cybersecurity Account Executive
$125K - $150K *
Join a team that's redefining enterprise cybersecurity sales, driving growth through innovative AI solutions. You'll engage with key stakeholders, own the sales cycle, and shape strategies for large e...
4 weeks ago
SME Microsoft 365 Administrator
$94K - $145K *
Lead the charge in optimizing Microsoft 365 operations, ensuring seamless administration and management of tenant subscriptions, Exchange online, and identity services while leveraging best practices...
Reposted 2 weeks ago
$75K - $158K *
Champion the Alteryx platform by ensuring secure, efficient operations and integration across enterprise analytics. Collaborate with cross-functional teams to enhance data-driven decision-making and a...
Reposted 1 week ago
Senior Program Manager - Data Security & Information Governance
$135K - $178K *
Transform data governance by leading initiatives that bridge legal compliance, data security, and technology operations. Drive innovative self-service workflows while ensuring compliance across divers...
Reposted yesterday
Senior Solutions Architect | SecOps (Remote)
$175K - $200K *
Elevate client security practices by architecting advanced SOC solutions, enhancing threat detection and exposure management capabilities. Lead high-impact engagements, translating complex security ne...
4 weeks ago
$83K - $125K *
Drive the operational health of mission-critical Appian environments, ensuring reliability and performance. Collaborate with cross-functional teams to manage configurations, deployments, and incident...
Yesterday
$140K - $228K *
Lead the charge in enhancing cybersecurity by driving detection engineering, incident response, and automation. Collaborate cross-functionally to secure cloud architectures and improve operational eff...
1 week ago
$135K - $150K *
Champion innovation by enhancing our cloud infrastructure and automating operations. Collaborate with cross-functional teams to drive AI-powered solutions and ensure software reliability in a dynamic...
3 weeks ago
Principal Specialist Sales Engineer, Zero Trust Branch - Healthcare/SLED
$175K - $251K *
Lead the charge in transforming customer experiences through innovative cloud security solutions, leveraging your expertise to craft tailored technical presentations and solutions that drive strategic...
Reposted 1 week ago
Mainframe Systems Programmer - DB2 Physical
$65K - $123K *
Join a team that's dedicated to providing expert DB2 support for mainframe clients. You'll manage database upgrades, maintenance, and performance tuning while ensuring timely solutions to enhance cust...
2 weeks ago
$99K - $159K *
Unlock the potential of AI in IT service management by implementing and optimizing ServiceNow tools. Collaborate with cross-functional teams to enhance knowledge management and ultimately deliver outs...
3 weeks ago
Systems Engineer III Cloud - Data Center
$110K - $130K *
Transform complex cloud and data center solutions by leading implementations, ensuring technical readiness, and delivering exceptional customer support throughout the project lifecycle. Drive innovati...
Yesterday
Oracle eBusiness Suite (EBS) Database Administrator
$129K - $175K *
Champion the optimization of mission-critical Oracle EBS environments, ensuring seamless database administration and support for complex financial systems. Collaborate with cross-functional teams to e...
1 week ago
Site Installation Quality Assurance Specialist
$135K - $216K *
Shape the future of aviation by ensuring the highest quality standards in site installations for critical FAA systems. This hands-on role requires expertise in construction inspection and quality assu...
4 weeks ago
$100K - $130K *
Drive your career forward by leading federal proposal efforts from start to finish. Collaborate with cross-functional teams to create compelling, compliant proposals for defense and civilian sectors...
3 weeks ago
DAI Data Integration/Replication Engineer
$75K - $158K *
Shape the future of federal data integration by leveraging Oracle EBS expertise to create actionable insights and advanced dashboards. Collaborate with cross-functional teams and enhance government da...
Reposted 1 week ago
Sr IT Project Specialist - HOH Fellows | SpouseWorks Fellows | SkillBridge Candidates Only
$90K - $94K *
Unlock potential by joining a dynamic team that supports military transitions into civilian roles. Gain hands-on experience in IT project management while collaborating with industry leaders to enhanc...
2 days ago
$110K - $130K *
Lead the charge in developing cloud strategies and governance frameworks for the Judiciary. Collaborate with stakeholders to enhance cloud adoption and ensure effective decision-making through compreh...
2 weeks ago
What is an Information Systems Security Officer (ISSO)?
An ISSO is a cybersecurity professional who helps protect an organization’s information systems by coordinating security controls, assessing risks, maintaining documentation, and supporting compliance and authorization activities.
What qualifications are commonly required for ISSO jobs?
Requirements vary, but employers commonly look for information security or IT experience, knowledge of security controls and risk management, and familiarity with relevant standards such as NIST guidance. Some positions may require a degree, professional certifications, or an active security clearance.
How much do Information Systems Security Officers earn?
Compensation varies by employer, location, experience, clearance, and job scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check each listing for its stated salary or compensation details.
Where do ISSOs work?
ISSO roles are found in government and defense contracting, technology, healthcare, financial services, and other industries that manage sensitive or regulated information.
How can I find ISSO jobs paying $100,000 or more?
Browse Information Systems Security Officer listings on Ladders and review each posting’s compensation, qualifications, location, and clearance requirements to find roles that fit your experience.