Information Systems Security Officer (ISSO) Jobs

Information Systems Security Officers help organizations protect sensitive data, systems, and networks. ISSOs assess security risks, guide teams through compliance requirements, and help ensure that information systems are designed and operated securely. Explore vetted ISSO opportunities on Ladders, including professional roles that pay $100,000 or more.

What Does an ISSO Do?

Responsibilities vary by employer and industry, but ISSOs commonly maintain security documentation, monitor system controls, coordinate risk assessments, and support authorization and compliance activities. They may work with system owners, security engineers, auditors, and government stakeholders to identify vulnerabilities and address findings.

Common ISSO Skills and Qualifications

Employers often seek experience in information security, risk management, security controls, and regulatory or government frameworks. Familiarity with standards such as NIST guidance, authorization processes, incident response, and security assessment practices can be valuable. Some roles require a bachelor’s degree, relevant certifications, security clearance, or experience supporting federal systems; requirements differ by position.

ISSO Career Opportunities

ISSO professionals work across government contracting, defense, technology, healthcare, financial services, and other sectors with complex security needs. Depending on experience, they may advance into senior ISSO, information assurance, cybersecurity program management, or security leadership roles. Browse current listings to compare responsibilities, qualifications, work arrangements, and compensation.

Find ISSO Jobs on Ladders

Use Ladders to explore vetted professional opportunities, including Information Systems Security Officer jobs with salaries of $100,000 or more. Review each listing for its specific pay range, location, clearance requirements, and experience expectations, then apply to roles aligned with your background.

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$132K - $207K *

Lead the charge in enhancing security for cutting-edge satellite ground solutions. As an Information System Security Officer, you'll oversee security compliance, risk management, and collaboration wit...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$110K - $150K *

Develop and maintain comprehensive security documentation for DoD systems, ensuring compliance with the Risk Management Framework (RMF). Collaborate with technical teams and stakeholders to manage sec...

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $150K *

Lead the implementation and validation of security controls across enterprise systems, ensuring compliance with federal cybersecurity standards while collaborating with engineering teams to enhance se...

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$103K - $181K *

Transform cybersecurity practices by ensuring robust system security for critical operations, supporting national defense initiatives through innovative solutions and expert collaboration in a dynamic...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$130K - $150K *

Optimize security compliance efforts by managing FedRAMP authorization, coordinating audits, and collaborating with engineering teams. Drive continuous improvement in cybersecurity practices while sup...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $216K *

Lead the charge in ensuring compliance and security for critical IC systems. Collaborate with engineers and government teams to maintain operational integrity while managing vulnerabilities and accred...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $130K *

Contribute to enhancing our security posture by identifying risks, implementing controls, and ensuring compliance with regulations. Collaborate with stakeholders to maintain incident response plans an...

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $150K *

Join a team that's dedicated to maintaining cybersecurity for large-scale programs. You'll ensure compliance, manage risks, and collaborate with technical teams to uphold security standards across var...

Today

  •   5 - 7 years exp.  •   Technical Services

$80K - $95K *

Redefine cybersecurity by ensuring operational security for IT systems. Collaborate with teams to implement policies, manage incidents, and maintain compliance, while enhancing the security posture at...

Today

  •   5 - 7 years exp.  •   Technical Services

$110K - $130K *

Manage risk assessments and security controls to ensure system authorization. Collaborate with IT staff to develop security procedures and maintain compliance with RMF and NIST standards, while addres...

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$115K - $130K *

Empower our cybersecurity efforts by managing risk and compliance for critical systems. Collaborate with teams to develop security documentation and provide guidance, ensuring adherence to DoD policie...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Transform cybersecurity practices by ensuring compliance with RMF requirements, managing ATO processes, and providing expert guidance to enhance the security posture of critical systems across diverse...

5 days ago

  •   Less than 5 years exp.  •   Technical Services

$110K - $135K *

Collaborate to enhance cybersecurity for critical defense programs, ensuring compliance and risk management for cloud and classified systems. Join a team dedicated to innovative solutions and operatio...

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Transform security operations by ensuring compliance and safeguarding information systems in DoD environments. Collaborate with teams to maintain security posture and manage risk while supporting Spec...

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Optimize security operations for DoD environments by managing information systems' security posture, ensuring compliance, and supporting Special Access Programs. Collaborate with teams to conduct asse...

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$88K - $105K *

Champion cybersecurity excellence by safeguarding classified information systems, ensuring compliance with industry standards, and supporting application development and network implementation for opt...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $130K *

Transform security protocols by leading risk management activities and ensuring compliance for diverse information systems. Collaborate with teams to enhance cybersecurity measures and protect critica...

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$110K - $130K *

Join our team as an Information System Security Officer, where you'll manage Risk Management Framework activities, ensuring compliance and security for diverse information systems while collaborating...

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$100K - $140K *

Pioneer cybersecurity excellence by managing system security controls, ensuring compliance with federal standards, and collaborating with cross-functional teams to protect mission-critical IT systems...

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$80K - $120K *

Join a team that's dedicated to enhancing cybersecurity for mission-critical IT systems. As a Senior Information Systems Security Officer, you'll implement security controls, assess risks, and ensure...

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Transform cybersecurity practices by ensuring compliance and security for mission-critical IT systems. Collaborate with cross-functional teams to assess risks, implement controls, and maintain system...

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Join a dynamic team to implement and manage cybersecurity measures, ensuring compliance with federal standards. Collaborate with cross-functional teams to assess risks and maintain the security postur...

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Lead cybersecurity initiatives by implementing and managing security controls, ensuring compliance with federal standards, and collaborating with cross-functional teams to protect mission-critical IT...

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Elevate cybersecurity operations by safeguarding DoD Special Access Program systems. Collaborate with teams to ensure compliance, manage risks, and enhance security documentation throughout system lif...

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $130K *

Transform the security landscape of classified information systems by managing day-to-day operations, ensuring compliance, and leading risk assessments. Collaborate with government officials to mainta...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What is an Information Systems Security Officer (ISSO)?question toggle

    An ISSO is a cybersecurity professional who helps protect an organization’s information systems by coordinating security controls, assessing risks, maintaining documentation, and supporting compliance and authorization activities.

  • What qualifications are commonly required for ISSO jobs?question toggle

    Requirements vary, but employers commonly look for information security or IT experience, knowledge of security controls and risk management, and familiarity with relevant standards such as NIST guidance. Some positions may require a degree, professional certifications, or an active security clearance.

  • How much do Information Systems Security Officers earn?question toggle

    Compensation varies by employer, location, experience, clearance, and job scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check each listing for its stated salary or compensation details.

  • Where do ISSOs work?question toggle

    ISSO roles are found in government and defense contracting, technology, healthcare, financial services, and other industries that manage sensitive or regulated information.

  • How can I find ISSO jobs paying $100,000 or more?question toggle

    Browse Information Systems Security Officer listings on Ladders and review each posting’s compensation, qualifications, location, and clearance requirements to find roles that fit your experience.