South Dakota, known for its diverse economy and strong job market, hosts a variety of high-paying job opportunities in different sectors. Whether you are looking for roles in healthcare, technology, finance, or other professional industries, Ladders has got you covered.
With a low unemployment rate and fast-growing industries, South Dakota is a promising place to level up your career. Explore the vast opportunities spread across the Mount Rushmore State with Ladders.
Navigate the professional job market in South Dakota with ease using our curated, vetted job postings. Join Ladders to discover the lucrative job opportunities in South Dakota that await you.
Average Salary: $119,458
Sr. Director, Integrated Evidence Generation Lead
$175K - $210K *
Lead pioneering evidence generation initiatives to inform oncology product strategies and lifecycle management through cross-functional collaboration and data-driven decision-making...
3 weeks ago
Executive Director, Global Medical Affairs Disease Area Lead, Solid Tumors
$296K - $376K *
Pioneer the execution of gynecologic and solid tumor Global Medical Affairs programs, ensuring strategic alignment, budget adherence, and collaboration across teams to drive clinical development and i...
Reposted 3 weeks ago
$210K - $250K *
Transform healthcare by delivering expert medical evaluation and treatment, ensuring top-notch patient care. Collaborate with a dedicated team to enhance health education and outcomes while maintainin...
3 weeks ago
Senior Manager - Automation - RCM
$89K - $151K *
Champion automation strategies to enhance efficiency in healthcare revenue cycles. Lead cross-functional teams in delivering innovative solutions while ensuring compliance and optimizing processes for...
3 weeks ago
RN Case Manager - Inpatient Days
$76K - $106K *
Drive effective resource management for patient care delivery across various settings. Collaborate with inter-professional teams to enhance clinical outcomes, promote patient wellness, and coordinate...
3 weeks ago
$120K - $130K *
Partner with us to conduct thorough medical evaluations for military applicants, ensuring compliance with standards while collaborating with healthcare teams to deliver outstanding care in a high-stak...
3 weeks ago
Associate Director, Medical Science Liaison - Southeastern PA / New Jersey
$197K - $247K *
Engage healthcare professionals to elevate expertise in hypertrophic cardiomyopathy and heart failure. Collaborate across functions to foster scientific exchange and support clinical development initi...
3 weeks ago
Content Solutions Analyst I (Certified Lab Coder)
$95K - $115K *
Transform your expertise into impactful solutions as you analyze and develop medical policies for genetic testing. Collaborate across teams while delivering high-quality insights in a fast-paced envir...
3 weeks ago
$90K - $105K *
Contribute to public health initiatives by analyzing congenital heart defect data, developing analytical plans, and supporting program operations to enhance health outcomes among affected populations...
3 weeks ago
$90K - $105K *
Empower public health initiatives by analyzing and ensuring quality data focused on congenital heart defects. Collaborate with stakeholders to enhance health outcomes through advanced statistical meth...
3 weeks ago
Senior Director, US Medical Lead LC-FAOD and MPSs
$270K - $334K *
Advance medical strategies for rare diseases, leading significant projects that unify scientific expertise and business acumen. Collaborate with teams to spearhead launches, data generation, and KOL e...
3 weeks ago
$86K - $106K *
Lead the charge in coordinating patient care by managing cases, ensuring seamless communication among patients, families, and providers, and resolving barriers to therapy. Focus on optimizing the pati...
Reposted 3 weeks ago
Director of Clinical Operations
$175K - $200K *
Transform clinical operations by leading a high-performing team to enhance patient experience, streamline processes, and ensure compliance while fostering innovation that drives organizational growth...
3 weeks ago
Medical Device & Diagnostics - CRA 2 - US Remote
$105K - $117K *
Deliver high-quality clinical monitoring in a fast-paced environment. Lead site management, ensure adherence to protocols, and guarantee participant safety. Collaborate effectively while adapting to c...
Reposted 3 weeks ago
Remote Sr. Director, Healthcare Analytics
$172K - $258K *
Advance innovative healthcare analytics programs by leading evaluations of clinical outcomes, ensuring clear metrics, and establishing best practices. Collaborate with cross-functional teams to drive...
3 weeks ago
Manager: Federal Healthcare Partnership Advisor
$113K - $188K *
Unlock transformative healthcare solutions by managing strategic engagements, optimizing partnerships between Military Health and Veterans Affairs, and guiding teams to enhance delivery systems for im...
Reposted 3 weeks ago
Registered Nurse (RN) | December 2026 and May 2027 New Grad
$67K - $100K *
Advance patient care by delivering compassionate nursing support, coordinating with healthcare teams, and implementing effective care plans. This role offers the opportunity to shape patient outcomes...
Reposted 3 weeks ago
Sr Manager, Global Scientific Communications & Engagement Strategy- Obesity Content Lead
$141K - $191K *
Empower healthcare innovation by leading strategic scientific communication initiatives in obesity treatment, ensuring impactful engagement with medical professionals through collaboration across func...
3 weeks ago
Staff Nuclear Pharmacist (Floater) - PET and SPECT
$125K - $150K *
Make your mark at a dynamic role, facilitating efficient pharmacy operations nationwide, providing technical support, promoting compliance, and building relationships while traveling extensively to va...
3 weeks ago
Clinical Operations Supervisor
$80K - $95K *
Help us optimize clinical operations by leading a team of nurses in delivering exceptional patient care and enhancing workflow adherence, quality, and compliance in a specialty pharmacy program...
Reposted 3 weeks ago
Director, Global Value, Access & Pricing; Solid Tumors, Pipeline
$183K - $243K *
Drive market access strategies for pipeline solid tumor products, ensuring alignment with clinical and commercial goals. Collaborate cross-functionally to address payer needs and enhance product posit...
Reposted 3 weeks ago
$80K - $133K *
Unlock your potential by providing essential reimbursement support and education to healthcare providers. Collaborate with medical teams to enhance patient access and streamline processes in a dynamic...
3 weeks ago
Supervising Physician for California
$200K - $250K *
Engage in transforming sleep care through a modern, evidence-based platform. Enjoy flexibility with 20 hours of patient care weekly, collaborate effectively, and shape the future of sleep medicine at...
3 weeks ago
$85K - $100K *
Join us to lead clinical informatics initiatives that optimize EHR usage, enhance workflows, and improve quality outcomes, fostering collaboration across clinical and operational teams while ensuring...
3 weeks ago
Manager, Value-Based Care Operations
$80K - $95K *
Lead the charge in enhancing value-based care operations by driving quality initiatives and optimizing processes across ACO programs. Collaborate with providers and stakeholders to ensure compliance a...
3 weeks ago
What kind of high-paying jobs are available in South Dakota?
South Dakota has a robust job market with high-paying positions in healthcare, IT, finance, manufacturing, and more.
Why should I consider working in South Dakota?
South Dakota is known for its diverse economy, low unemployment rate, and range of industries. It's a great location for professionals looking to advance their careers.
Can I find jobs that pay over $100000 in South Dakota?
Yes, at Ladders you can find many jobs in South Dakota that pay over $100000.
How can Ladders help me in finding high-paying jobs in South Dakota?
Ladders provide vetted, high-paying job postings and tools to help you navigate the professional job market in South Dakota.