Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,869

Sort By: Relevance

$93K - $120K *

Join a dynamic team as you manage clinical data throughout study lifecycles, ensuring compliance and quality. Collaborate with cross-functional teams to drive data strategy and support innovative solu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$67K - $199K *

Elevate product strategy and execution for Epic EHR solutions, driving user-centric design and agile methodologies. Collaborate with stakeholders to enhance healthcare delivery through innovative info...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$63K - $98K *

Support your career by providing essential nursing care in a correctional facility. Collaborate with a dedicated team to enhance the health and well-being of clients while adapting to dynamic environm...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$120K - $155K *

Empower patients by delivering compassionate, patient-centered palliative care through virtual consultations. Collaborate with a dynamic team to enhance quality of life for members with complex needs...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Champion clinical services initiatives, driving strategic content development and mentoring teams to enhance market access and client success. Lead projects, ensure compliance with standards, and reso...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Champion innovative healthcare research by leading complex evaluations and business development initiatives, fostering collaboration among diverse experts to enhance Medicare and Medicaid services and...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Lead clinical pharmacy operations in oncology, providing patient care, education, and medication management. Collaborate with healthcare teams to enhance pharmacy services and support residency traini...

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Unlock potential by providing expert support and training for Nuclear Medicine and PET customers, enhancing satisfaction and service quality for CardioGen-82 users through education, troubleshooting...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K *

Champion the delivery of quality care as a Licensed Nursing Home Administrator, overseeing daily operations and ensuring compliance with regulations while fostering effective relationships in a dynami...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$108K - $171K *

Join us to lead clinical development for an innovative AI cardiometabolic care solution. Collaborate cross-functionally to ensure clinical excellence in product features, workflows, and member experie...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$297K - $367K *

Grow your career with a pivotal role driving hospital data integration and compliance. Lead execution of clinical data operations, build relationships, and ensure secure data handling while shaping a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Shape impactful healthcare solutions by leveraging your Epic Professional Billing expertise. Collaborate with diverse teams to optimize systems, enhance workflows, and drive meaningful results for cli...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$143K - $243K *

Champion innovative clinical strategies in specialty pharmacy, overseeing services and solutions to enhance client value and outcomes. Collaborate with cross-functional teams to drive program performa...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$76K - $131K *

Join a team that's redefining healthcare compliance by leading detailed coding audits, mentoring auditors, and driving innovative solutions to enhance compliance and operational excellence in a dynami...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$76K - $131K *

Elevate healthcare compliance by leading detailed coding audits, mentoring auditors, and implementing action plans. Drive innovation and ensure adherence to standards while fostering a culture of cont...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$241K - $337K *

Transform your career with a flexible role in primary care, serving a diverse patient population. Collaborate with a dedicated team in a supportive environment, offering both part-time and full-time o...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$68K - $105K *

Champion the implementation and support of Epic Beaker applications, ensuring effective system design, user experience, and problem resolution while managing projects and enhancing end-user engagement...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$195K - $277K *

Drive innovative clinical oncology studies by designing protocols, collaborating with teams, and ensuring compliance with regulations. Leverage expertise to analyze data, support publications, and mai...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$119K - $179K *

Support the integration and harmonization of clinical data by designing FHIR-compliant models and pipelines, ensuring data accuracy and usability for patient care and research initiatives across the o...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$92K - $167K *

Drive strategic initiatives in Medicare Advantage provider networks, analyzing data and collaborating with leadership to enhance performance and achieve goals. Lead complex projects from inception to...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Drive strategic excellence in healthcare by leading business development, planning, and population health initiatives. Collaborate with teams to ensure that the mission and values guide MercyOne’s evo...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$164K - $273K *

Join a team that's advancing global scientific engagement through strategic conference planning and execution. Collaborate across functions to elevate medical affairs and enhance the impact of evidenc...

RemoteRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$140K - $185K *

Accelerate progress at the forefront of payor relations, leading a team to develop strategic partnerships that enhance patient access and optimize reimbursement for innovative medical technologies in...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$79K - $127K *

Partner with us to deliver comprehensive case management services, ensuring quality care and optimal health outcomes for members with complex needs. Collaborate with healthcare teams to develop and im...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$108K - $114K *

Join a team that's dedicated to enhancing patient care as a Speech Language Pathologist. Collaborate with health professionals in a supportive environment, providing essential therapy services to impr...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.