Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Healthcare Jobs in Iowa

Average Salary in USD

Average Salary: $109,869

Sort By: Relevance

$90K - $110K *

Engage in dynamic emergency medicine as an Advanced-Practice Provider, collaborating with a dedicated team to enhance patient care and well-being in a supportive, multi-specialty clinic environment...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Join a team that's dedicated to ensuring safe and effective radiation therapy delivery. Collaborate with oncologists and clinical staff to uphold treatment accuracy, regulatory compliance, and patient...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $110K *

Empower patient care by coordinating cardiology services, performing assessments, and managing outpatient and inpatient needs. Collaborate with a multidisciplinary team to enhance patient outcomes and...

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$101K - $146K *

Elevate the insurance verification and authorization process by managing staff, developing strategies, and ensuring excellent service delivery while resolving complex patient financial needs in a coll...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $140K *

Transform patient care by leading a team of Field Clinical Specialists, ensuring high-quality clinical education and support. Drive clinical outcomes through effective management, collaboration, and c...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$72K - $97K *

Accelerate progress at clinical trials by supporting regional study delivery, ensuring quality standards, and collaborating with key stakeholders to meet study goals within timelines and budget...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$146K - $189K *

Partner with us to enhance our community health provider network. Leverage your expertise in provider relations and network management to drive growth, improve access to care, and support our mission...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$130K - $155K *

Elevate your career by joining a dynamic Medical Affairs team, where you'll lead Medical Information initiatives, ensure compliance, and drive strategic insights to support our innovative pipeline in...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$186K - $233K *

Pioneer innovative strategies in breast oncology, driving commercial success through collaboration and data-driven insights. Lead cross-functional teams to enhance product adoption and optimize market...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$173K - $200K *

Elevate rebate product strategy by leading development, driving growth, and enhancing operational performance. Collaborate across teams to ensure compliance and deliver measurable outcomes that align...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$125K - $235K *

Champion healthcare coding excellence by optimizing operations, implementing automation, and enhancing training. Collaborate with leaders to drive measurable improvements in productivity and accuracy...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $100K *

Join a team that's dedicated to transforming veterinary care with flexible schedules, clinical autonomy, and a supportive community. Enjoy a balanced work-life while delivering exceptional medical ser...

3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$110K - $130K *

Reimagine medical communication by leading a team of writers to craft regulatory and scientific documents. Oversee projects, ensuring clarity and quality for diverse audiences while adhering to timeli...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Join a team that's dedicated to enhancing patient care in cardiology. This role involves providing comprehensive support, education, and coordination for patients with cardiovascular conditions, ensur...

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$74K - $98K *

Champion regulatory audit excellence by leading PACE audits, ensuring compliance, and driving cross-functional collaboration to enhance operational readiness and continuous improvement across the orga...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $322K *

Provide comprehensive medical care and consultation for incarcerated patients, ensuring quality treatment through interdisciplinary collaboration and emergency response while maintaining compliance wi...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Join a team that's redefining oncology care by overseeing clinical standards, evaluating therapies, and engaging with providers. You'll play a key role in shaping patient eligibility and treatment pro...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $90K *

Shape the future of Cell and Gene Therapy by providing expert application support, driving customer integration, and enhancing product utilization through collaboration and technical guidance across t...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a team that's enhancing pharmacy services through innovative technology and clinical expertise. Drive medication safety initiatives, optimize automated systems, and collaborate with diverse teams...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Shape the future of surgical care by leading a dedicated team, fostering collaboration, and ensuring high-quality patient outcomes while managing departmental resources and compliance with regulations...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$81K *

Empower the well-being of residents by delivering quality nursing care through established practices and standards, while fostering teamwork and leadership in a supportive environment focused on indiv...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$73K - $110K *

Elevate your career by ensuring coding accuracy and compliance in a dynamic healthcare environment. Collaborate with teams to enhance documentation quality and drive improvements in coding practices w...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$132K - $178K *

Champion quality in In-Vitro Diagnostics and Companion Diagnostics. Lead proactive strategies, ensuring compliance in clinical trials while collaborating with partners to enhance precision medicine in...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $235K *

Join a team that's shaping the future of Medical Affairs by driving strategic client engagements and enhancing capabilities. This Director-level role balances client delivery and internal growth, focu...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Elevate healthcare revenue integrity by leading client engagements focused on optimizing revenue cycles, enhancing compliance, and driving financial performance through strategic recommendations and d...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.