Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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Healthcare Analyst Jobs in Pennsylvania

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$125K - $145K *

Shape the future of data governance by leading methods and standards across enterprise systems. Collaborate with teams to define quality rules and documentation, ensuring consistency and excellence in...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$94K - $293K *

Unlock potential by leading innovative Data Science and AI initiatives. Manage diverse teams, bridge business and technical domains, and drive strategic solutions that enhance decision-making and deli...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$87K - $293K *

Drive innovative AI and Data Science solutions by managing end-to-end projects, leading teams, and collaborating across functions to enhance decision-making and deliver value for clients in a dynamic...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$210K - $250K *

Empower patient health by delivering comprehensive primary care services, focusing on preventive care and disease management. Collaborate with a multidisciplinary team to enhance patient outcomes and...

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$126K - $211K *

Elevate customer relationships by driving growth within oncology practices. Utilize a consultative approach to align solutions with client objectives and collaborate with internal teams to enhance bus...

RemoteRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$250K - $300K *

Join a team that's dedicated to advanced treatment and research in myeloid malignancies. Lead, innovate, and collaborate in a growing hematology program focusing on exceptional patient care and the ev...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$104K - $166K *

Shape the future of healthcare by delivering comprehensive in-home primary care, managing chronic diseases, and collaborating with an interdisciplinary team to enhance patient outcomes and prevent hos...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Join a leading healthcare system as an Anesthesiologist, providing comprehensive anesthetic care across diverse surgical cases. Collaborate with a multidisciplinary team, engage in teaching, and contr...

4 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$140K - $270K *

Unlock your potential by managing ML systems at scale, ensuring uptime and observability. Collaborate on deploying and scaling models, while enhancing platform reliability through advanced engineering...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$101K - $152K *

Champion innovative solutions by leveraging Epic expertise to enhance operational efficiency and drive strategic initiatives across healthcare environments, ensuring high-performance standards and cli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Champion enterprise data architecture by establishing standards and a unified data catalog. Collaborate across teams to define metrics and ensure data governance, driving alignment and clarity in a ha...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$92K - $110K *

Join a team that's dedicated to enhancing software quality and reliability. As a Business Analyst, you'll collaborate with cross-functional teams to gather requirements, facilitate Agile processes, an...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Engage in the development and deployment of innovative cybersecurity solutions, leading efforts to enhance network defense and incident response across a global enterprise while collaborating with mis...

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$75K - $137K *

Lead the charge in enhancing our security posture by evaluating alerts, mitigating risks, and leveraging advanced security technologies. Collaborate with teams to ensure effective incident response an...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Lead the design and delivery of impactful training programs, creating engaging learning materials and facilitating sessions to enhance employee skills and knowledge across various business units. Driv...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$135K - $160K *

Transform healthcare technology by owning core products, driving architectural decisions, and ensuring high-quality code. Collaborate across teams to deliver impactful solutions that enhance patient c...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $200K *

Lead the charge in managing complex Life Sciences programs, ensuring alignment with customer commitments. Drive delivery across teams, proactively addressing risks and building a PMO as the business s...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$101K - $203K *

Redefine the financial landscape by delivering in-depth analysis and insights that drive strategic finance and advisory decisions, while guiding junior team members and supporting M&A initiatives, all...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Innovate clinical quality systems for scalable care delivery, ensuring standards meet payer expectations and driving measurable performance improvements across independent health providers...

RemoteRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Shape the future of API management by designing and deploying robust solutions across diverse environments, ensuring seamless integration and operational excellence while mentoring clients to maximize...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $180K *

Unlock potential by leading product marketing initiatives that empower healthcare teams. Drive sales enablement, module marketing, and customer expansion, while shaping messaging and content that reso...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$123K - $207K *

Elevate enterprise systems by leading design and enhancements, ensuring reliability and usability. Collaborate with cross-functional teams to translate requirements into scalable solutions while drivi...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$170K - $200K *

Pioneer innovative solutions by leading client engagements with top firms. Drive discovery, connect needs to data insights, and collaborate across teams to deliver impactful results in a dynamic, remo...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$170K - $190K *

Transform data into actionable insights by leading a team of data scientists and analysts. Drive advanced analytics initiatives, foster collaboration with stakeholders, and ensure high-quality deliver...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $120K *

Elevate clinical trial success by providing expert oversight and guidance. Collaborate with cross-functional teams to ensure compliance, quality, and timely execution of monitoring activities while fo...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.