Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.
Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.
Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.
Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.
Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.
Senior Analyst, ALM & Treasury
$88K - $141K *
Empower financial strategies by analyzing interest rate and liquidity risks. Collaborate with stakeholders to enhance capital planning and reporting processes while ensuring compliance with regulation...
1 week ago
Publications and Scientific Communications Lead
$100K - $120K *
Lead scientific operations for clinical research projects, ensuring quality and efficiency. Collaborate with teams to develop strategies, manage protocols, and drive innovation while maintaining stake...
3 weeks ago
Applied Data Scientist – Performance Management & AI Solutions
$87K - $157K *
Innovate solutions by leveraging data, AI, and analytics to enhance operational performance. Collaborate with cross-functional teams to transform complex challenges into actionable insights, driving m...
2 weeks ago
Technical Account Manager - Healthcare
$95K - $115K *
Drive the technical relationship with healthcare accounts, ensuring platform adoption, risk mitigation, and customer growth through proactive advisory and strategic planning. Collaborate with IT teams...
1 week ago
Associate Director, Talent Analytics & Assessment Science
$132K - $193K *
Unlock potential by leading the enterprise employee listening strategy, enhancing assessment science, and applying analytics to drive data-informed talent decisions. Collaborate with cross-functional...
2 weeks ago
Senior Financial Analyst, FP&A (R&D)
$111K - $167K *
Transform financial operations by driving monthly close processes, managing forecasts, and leveraging AI for process improvements while serving as a key business partner to leadership to enhance strat...
Reposted 5 days ago
$133K - $180K *
Join a team that's redefining member experiences by architecting optimal journeys, bridging operational execution with strategic vision to enhance engagement and satisfaction across all touchpoints...
Reposted 6 days ago
Director of Insurance Plan Management
$120K - $150K *
Transform the landscape of dental negotiations by leading strategic partnerships with payers, optimizing contracts, and driving revenue growth through data-driven insights and collaborative execution...
2 weeks ago
EHR Applications Manager - Pharmacist
$110K - $130K *
Lead the development and optimization of the Epic EHR platform, ensuring secure and scalable functionality. Collaborate with teams to enhance workflows, guide analysts, and implement improvements for...
1 week ago
EHR Applications Manager - Pharmacist
$110K - $130K *
Shape the future of healthcare by leading the Epic EHR platform's development and optimization. Ensure secure, scalable functionality while guiding teams in enhancing clinical workflows and operationa...
1 week ago
Business Communications Lead Analyst - Cigna Healthcare - Remote
$95K - $115K *
Lead the charge in advancing business priorities through strategic communications that engage and inspire stakeholders globally. Collaborate across functions to create impactful content and drive enga...
1 week ago
Business Communications Lead Analyst - Cigna Healthcare - Remote
$100K - $120K *
Shape the future of strategic communications by driving engagement and alignment across a global organization. Collaborate with leaders to create impactful content and manage initiatives that connect...
1 week ago
Care Manager, Telephonic Nurse
$71K - $97K *
Transform patient care by guiding transitions and ensuring optimal service continuity. Leverage your nursing expertise to navigate healthcare options and advocate for patients in need of post-acute se...
3 days ago
Salesforce Senior Business Analyst
$110K - $150K *
Empower your career by leading client engagements and analysis within our dynamic Salesforce practice. Collaborate with a supportive team to deliver innovative solutions that address current challenge...
Reposted 4 days ago
$112K - $132K *
Join a team that's shaping the future of autism care by building robust statistical methodologies. You'll analyze real-world clinical data, ensuring rigorous evaluation of outcomes and social validity...
4 days ago
Life Sciences Data Management, Lead (MDM/DGov)
$134K - $265K *
Unlock potential by leading Customer MDM and Data Governance initiatives in Life Sciences. Drive AI-powered solutions, enhance commercial operations, and foster innovation while managing client engage...
1 week ago
Life Sciences Data Management, Lead (MDM/DGov)
$134K - $265K *
Elevate your career by leading innovative Customer MDM and Data Governance initiatives in Life Sciences. Drive strategic engagements, optimize data solutions, and foster high-performing teams to enhan...
1 week ago
Environmental, Health Safety- Regulatory Analyst
$80K - $95K *
Advance your career by optimizing EHS regulatory processes and data management. Collaborate with teams to ensure compliance, manage violations, and enhance reporting systems in a dynamic environment f...
3 days ago
$168K - $231K *
Join a dynamic team to lead Nurse Case Managers, enhancing patient support and education throughout treatment journeys while ensuring compliance and quality in case management processes...
1 week ago
Clinical Application Specialist - DCAR
$92K - $138K *
Join a dynamic team to deliver clinical education and support for diagnostic cardiology solutions, enhancing customer experience and driving successful outcomes through expert training and collaborati...
3 days ago
Certified Registered Nurse Practitioner/Physician Assistant (FT Pediatrics)
$90K - $110K *
Lead the charge in delivering exceptional pediatric care by supporting physicians and enhancing patient experiences. Collaborate with a dedicated team to assess, plan, and implement effective treatmen...
1 week ago
Certified Registered Nurse Practitioner/Physician Assistant (FT Pediatrics)
$90K - $110K *
Empower patient care by joining a dedicated team of healthcare professionals. Utilize your pediatric expertise to assess, plan, and deliver high-quality care in a collaborative environment focused on...
1 week ago
Head of AI Clinical Excellence
$176K - $294K *
Strategize AI-driven solutions that enhance Clinical Development processes and decision-making. Collaborate with cross-functional teams to implement innovations, improve efficiency, and ensure regulat...
Reposted 6 days ago
$104K *
Champion a comprehensive approach to patient care through assessment, diagnosis, and therapeutic services in an outpatient setting, ensuring adherence to ethical guidelines and delivery of culturally...
Reposted 3 days ago
Pharmacist - Jefferson Cancer Center
$100K - $120K *
Join us to optimize patient care through safe, effective pharmaceutical practices. Oversee drug dispensing, monitor therapy, and collaborate with healthcare teams to enhance patient outcomes while man...
1 week ago
What kinds of high-paying jobs can I find in Pennsylvania?
Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.
Do Pennsylvania jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.
How can I narrow my search for jobs in Pennsylvania?
Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.
Are remote or hybrid jobs available in Pennsylvania?
Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.