Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs offering salaries of $100,000 or more, from leadership positions to specialized roles. Whether you’re targeting a new opportunity in Columbus, Cleveland, Cincinnati, or another Ohio community, find openings that match your experience and career goals.

Find Opportunities Across Ohio

Ohio’s job market spans major metropolitan areas and a wide range of industries. Search roles in cities such as Columbus, Cleveland, and Cincinnati, as well as opportunities throughout the state. Availability varies by employer and location, so explore current listings to see where your skills are in demand.

Explore Professional Roles and Industries

High-paying Ohio openings may include positions in technology, healthcare, finance, manufacturing, sales, and operations. Listings can range from experienced individual-contributor roles to director, vice president, and executive positions. Review each posting for its responsibilities, qualifications, location, and compensation details.

Make Your Ohio Job Search More Focused

Use Ladders to narrow your search by role, location, and other preferences. Tailor your resume to highlight relevant achievements, leadership experience, and measurable results. Check listings regularly and apply to opportunities that align with your qualifications and compensation expectations.

Discover Your Next Career Move

Find vetted professional jobs paying $100,000 or more in Ohio on Ladders. Browse current openings and take the next step toward a role that fits your experience and ambitions.

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$150K - $268K *

Drive state and local government relations across 25 states, managing legislative efforts and stakeholder engagement to advance business goals. Collaborate with internal teams and external partners to...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$83K - $107K *

Unlock potential by guiding families through pediatric oncology care. Engage closely with multidisciplinary teams to coordinate complex treatment plans and ensure seamless transitions between inpatien...

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$106K - $260K *

Unlock powerful data capabilities by leading the development of a cutting-edge real-time transactional cache platform designed to enhance API access and streamline operational data flows across enterp...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a team that's dedicated to delivering exceptional cardiology care. As an Acute Care Nurse Practitioner or Physician Assistant, you'll collaborate with healthcare teams to provide personalized, hi...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Engage with healthcare services and technology leaders to drive new business growth. Leverage a robust support system to build relationships, execute territory plans, and expand existing accounts whil...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Contribute to impactful SaaS implementations, guiding clients through setup, data migration, and training while leading complex projects to success across municipal government sectors...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$74K - $118K *

Elevate compliance standards by leading oversight initiatives, managing complex projects, and collaborating across teams to ensure regulatory adherence and effective governance in a dynamic environmen...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$151K - $209K *

Lead the strategic management of a VA health care facility, ensuring high-quality patient care and operational excellence. Collaborate with executive leadership to drive program goals, enhance service...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$135K - $170K *

Accelerate growth by managing strategic healthcare accounts, driving new business, and enhancing relationships. Collaborate with cross-functional teams to address complex identity challenges and deliv...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$104K - $166K *

Join a team that's dedicated to enhancing cybersecurity operations by monitoring, analyzing, and responding to security incidents. Leverage your expertise to protect critical systems and mentor junior...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$150K - $175K *

Lead the charge in delivering insights through advanced research and analysis, managing multiple projects, guiding team performance, and enhancing client relationships in the life sciences consulting...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Unlock potential by bridging business and technical teams to define and implement master data management and governance solutions, ensuring data quality and compliance across the organization...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$74K - $98K *

Elevate quality operations by leading corrective action plans (CAPs) for regulatory compliance. Collaborate with cross-functional teams to drive accountability, resolve barriers, and ensure sustained...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to enhancing clinical trial processes through effective management, budget negotiation, and regulatory support, while building collaborative relationships with research in...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $120K *

Analyze and enhance business processes across the services lifecycle. Develop reporting solutions and dashboards to drive informed decisions, improve revenue predictability, and support stakeholders i...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Unlock potential by leading the data engineering strategy for a transformative healthcare platform. Drive interoperability, oversee data integrations, and build a high-performing team to enhance patie...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$88K - $105K *

Empower nursing education by leading strategic program management initiatives. Coordinate across multiple programs, enhance processes, and engage stakeholders to strengthen the student-to-nurse pipeli...

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$90K - $95K *

Champion the analysis of Low-Income Housing Tax Credit projects, leveraging strong financial acumen to prepare investment models and reports. Collaborate with developers and manage multiple assignment...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$61K - $98K *

Empower your career by analyzing commercial insurance pricing while utilizing AI and automation. Collaborate with profit centers to deliver actionable insights, support rate filings, and enhance profi...

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$85K - $102K *

Engage with stakeholders to manage a complex portfolio of clinical and non-clinical projects. Drive strategic initiatives by collaborating across teams to ensure alignment, effective execution, and pr...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$71K - $89K *

Lead the charge in strategic fundraising initiatives, managing a portfolio of 125 major gift prospects, including alumni and corporate partners. Cultivate and solicit gifts ranging from $100K to $250K...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$77K - $115K *

Join a team that's driving innovation in IT solutions by leveraging your expertise in systems analysis and functional design. Collaborate with cross-functional teams to enhance business processes and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Deliver innovative solutions by enhancing AI agent capabilities, debugging runtime issues, and building testing tools. Collaborate closely with client data and improve system performance in a dynamic...

RemoteRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $150K *

Transform data engineering practices by leading innovative projects that enhance data sharing and analysis across organizations, driving mission-critical insights and collaboration within a dynamic te...

4 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$80K - $85K *

Grow your career with a dynamic team focused on client success, managing relationships, and delivering tailored solutions. Drive satisfaction and retention while collaborating across departments to en...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Ohio listings may include professional, senior, leadership, and executive roles across fields such as technology, healthcare, finance, manufacturing, sales, and operations. Available positions vary, so check current postings for details.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Opportunities may be available in Columbus, Cleveland, Cincinnati, and other Ohio communities. Search by location to see current openings near you or in a city where you’d like to work.

  • How can I find Ohio jobs that pay at least $100,000?question toggle

    Browse Ohio listings on Ladders and review each posting’s compensation information, location, and qualifications. Use available search filters to focus on roles that fit your experience and goals.

  • Are all Ohio jobs on Ladders remote or on-site?question toggle

    Work arrangements vary by employer and position. Review each listing for its location and whether it describes the role as on-site, hybrid, or remote.