Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Population Health Care Manager Complex Care Management
$80K - $95K *
Contribute to patient care by managing complex cases, coordinating discharge plans, and ensuring effective transitions across healthcare settings. Collaborate with teams to optimize resources and main...
1 week ago
$104K - $166K *
Join a team that's dedicated to enhancing cybersecurity operations by monitoring, analyzing, and responding to security incidents. Leverage your expertise to protect critical systems and mentor junior...
4 days ago
$70K - $180K *
Drive impactful healthcare technology solutions through data-driven strategies, optimize customer engagements with compelling insights, and foster long-term partnerships for strategic growth...
Reposted today
Business Analyst - MDM & Data Governance
$95K - $115K *
Unlock potential by bridging business and technical teams to define and implement master data management and governance solutions, ensuring data quality and compliance across the organization...
2 weeks ago
Registered Nurse, Atrium Health University City, Dialysis, Full Time Days
$79K - $118K *
Help us enhance patient care by utilizing your nursing expertise to assess, plan, and implement effective care strategies. Collaborate with a dedicated team to ensure safety and quality outcomes in a...
Reposted 5 days ago
Senior Quality Operations Specialist, CAP & Monitoring
$74K - $98K *
Elevate quality operations by leading corrective action plans (CAPs) for regulatory compliance. Collaborate with cross-functional teams to drive accountability, resolve barriers, and ensure sustained...
2 weeks ago
$68K - $103K *
Empower patient care by performing CT scans and assisting in procedures. Ensure quality imaging, maintain safety standards, and provide exceptional support to patients and medical staff in a dynamic h...
1 week ago
Senior Business Analyst, Professional Services (Req #1417)
$90K - $120K *
Analyze and enhance business processes across the services lifecycle. Develop reporting solutions and dashboards to drive informed decisions, improve revenue predictability, and support stakeholders i...
Reposted 3 weeks ago
$74K - $125K *
Lead the charge in modernizing a federal agency's data ecosystem. Collaborate with stakeholders to translate needs into actionable features, ensuring backlog readiness and supporting AI initiatives in...
2 weeks ago
Director, Enterprise Enablement
$150K - $180K *
Drive transformative AI initiatives across departments by leading a strategic team in designing scalable, agentic workflows that enhance decision-making and efficiency, ensuring measurable business ou...
Reposted today
Registered Nurse (RN) Behavioral Health Adults-One South
$79K - $118K *
Join a team that's dedicated to providing compassionate care in a dynamic behavioral health setting. As an RN, you'll coordinate patient care, utilizing evidence-based practices to ensure safety and e...
1 week ago
$90K - $95K *
Champion the analysis of Low-Income Housing Tax Credit projects, leveraging strong financial acumen to prepare investment models and reports. Collaborate with developers and manage multiple assignment...
3 weeks ago
Registered Nurse (RN) - Admission Discharge Transition Unit
$79K - $118K *
Elevate your nursing career by joining a dynamic Medical-Surgical Telemetry unit, providing comprehensive patient care in a Level 1 Trauma Center. Collaborate with experienced professionals to ensure...
3 days ago
$77K - $115K *
Join a team that's driving innovation in IT solutions by leveraging your expertise in systems analysis and functional design. Collaborate with cross-functional teams to enhance business processes and...
1 week ago
Area Director Clinical Ops & Engagement
$100K - $120K *
Transform patient care by leading a dedicated clinical team, enhancing operational efficiency, and ensuring compliance with healthcare standards while fostering a culture of excellence and collaborati...
1 week ago
Area Director Clinical Ops & Engagement
$100K - $120K *
Champion clinical excellence by leading a dedicated care team, enhancing patient satisfaction, and ensuring compliance with healthcare standards while driving operational efficiency and team engagemen...
1 week ago
Area Director Clinical Ops & Engagement
$110K - $130K *
Transform healthcare delivery by leading clinical operations and enhancing team performance. Drive patient satisfaction and compliance while managing a dedicated care team to ensure quality services f...
1 week ago
Account Manager- Client Success
$80K - $85K *
Grow your career with a dynamic team focused on client success, managing relationships, and delivering tailored solutions. Drive satisfaction and retention while collaborating across departments to en...
5 days ago
Business Analyst, New Construction Sales Analytics
$89K - $150K *
Optimize sales operations by managing forecasting and data analytics to enhance revenue delivery. Collaborate with cross-functional teams to ensure data accuracy and support sales processes, enabling...
1 week ago
$127K - $243K *
Transform investment management by leading research, analysis, and reporting. Drive efficiencies and ensure compliance while mentoring team members. Collaborate with senior leaders to enhance portfoli...
1 week ago
Senior Business Systems Analyst
$75K - $158K *
Drive enterprise-level technical solutions by analyzing system needs, coordinating design activities, and ensuring compliance with governance processes. Leverage your expertise to enhance performance...
Reposted 1 week ago
Client Growth & Success Principal Manager- Enterprise Accounts
$150K - $175K *
Shape the future of client partnerships by driving strategic growth and success for large enterprise organizations. Collaborate with cross-functional teams to deliver exceptional value and measurable...
1 week ago
Medical Technologist GCM Lead Tech Mountain Island
$73K - $110K *
Join a team that's dedicated to ensuring quality and safety in clinical lab operations. Lead and mentor staff while maintaining accreditation standards and enhancing efficiency in a fast-paced environ...
Reposted 1 week ago
$110K - $130K *
Transform your career by leading complex software projects and delivering high-quality solutions. Collaborate across teams to shape the future of our systems while mentoring peers and advocating for e...
1 week ago
Innovation Associate - Wake Forest University School of Medicine (WFUSM)
$79K - $118K *
Drive innovation by overseeing tech assessments, engaging with researchers, and managing commercialization strategies in a dynamic team environment. Support diverse projects and enhance outreach to se...
Reposted 3 weeks ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.