Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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Healthcare Analyst Jobs in Missouri

Sort By: Relevance

$170K - $212K *

Elevate AI security by designing robust frameworks to protect systems from threats. Collaborate with cross-functional teams to ensure compliance and ethical use, while implementing strategies that saf...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$182K - $198K *

Build and lead a robust Service Management Office to enhance IT operations, ensuring effective governance, accountability, and continuous improvement across a complex 24x7 environment, while fostering...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$88K - $105K *

Join a dynamic team as you lead HR initiatives, fostering a high-performance culture that empowers employees and drives organizational success. Collaborate with leadership to enhance recruitment, trai...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$130K - $155K *

Unlock potential by rapidly transforming customer insights into innovative prototypes. Collaborate with a dynamic team to build scalable products from scratch, leveraging AI tools and existing platfor...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$188K - $245K *

Drive the vision for a unified longitudinal patient record, ensuring data accuracy and completeness across multiple sources. Collaborate with cross-functional teams to enhance clinical data utility an...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Lead the consolidation of financial models and metrics, partnering with cross-functional teams to deliver actionable insights and support strategic decision-making across the organization...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $375K *

Join a team that's transforming life sciences through strategic commercial leadership. Drive large-scale engagements, foster client relationships, and deliver innovative solutions that enhance operati...

2 weeks ago

  •   11 - 15 years exp.  •   Business Services

$100K - $231K *

Unlock potential by leading strategic capture management initiatives, collaborating with cross-functional teams to enhance proposal quality and win probability in Medicaid managed care. Drive innovati...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$109K - $144K *

Join a team that's driving strategic payroll initiatives and enhancing operational effectiveness. You'll lead program execution, optimize Workday Payroll systems, and foster collaboration across depar...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Shape client success by leading complex consulting projects, integrating diverse workstreams into actionable insights, and driving high-quality deliverables while fostering team growth and managing st...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $450K *

Inspire innovation in global therapeutic strategies, leading scientific expertise and operational execution across a diverse therapeutic landscape, while ensuring high-quality delivery and compliance...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$65K - $109K *

Partner with us to foster strategic relationships, optimize account performance, and drive engagement with key stakeholders, leveraging your knowledge of healthcare technology to deliver impactful sol...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Contribute to impactful consulting services in government pricing, leveraging your expertise to guide clients through compliance, data analysis, and strategic initiatives while leading a collaborative...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$69K - $95K *

Join a team that's dedicated to leveraging data analytics to drive sales success. As a key partner, you'll provide insights and innovative solutions that enhance decision-making and support strategic...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$163K - $220K *

Shape the future of healthcare by leading analytics for managed care, driving payer strategies, and delivering insights to enhance access to medical benefit products. Collaborate with cross-functional...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$250K - $300K *

Lead the charge in providing exceptional critical care for complex patients. Join a dynamic team at a tertiary teaching hospital, engaging in bedside care, education, and research while enjoying a sup...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$115K - $193K *

Drive innovation in pharmacy automation software development, enhancing efficiency and accuracy. Collaborate cross-functionally to tackle complex challenges and see the impact of your contributions on...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$240K - $300K *

Contribute to a leading cancer program by joining a collaborative team of experts in head & neck surgery, focusing on microvascular reconstruction and oncology, while enjoying a balanced lifestyle and...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Advance client relationships and team performance as a strategic leader, overseeing captive insurance operations, driving excellence, and enhancing service delivery while managing complex engagements...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$215K - $240K *

Shape the future of drug development by leading analytical strategies, ensuring compliance and optimization of processes across lifecycle stages, and collaborating with cross-functional teams and exte...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$325K - $375K *

Lead the charge in driving revenue growth by building and mentoring a high-performing sales team in the Mid-Enterprise segment, focusing on customer acquisition and market penetration in a competitive...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$140K - $180K *

Champion innovation by developing full-stack web applications using TypeScript. Collaborate in a dynamic, remote-first team to deliver engaging user experiences, streamline operations, and lead techni...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Drive customer success by managing enterprise accounts, ensuring adoption and satisfaction with cybersecurity solutions. Collaborate cross-functionally to deliver value and strategic alignment through...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$128K - $226K *

Unlock potential by leading the delivery of APIs and integrations that enhance healthcare tools. Collaborate with engineering teams to ensure reliable, user-friendly solutions that drive business grow...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$73K - $127K *

Join our dynamic Outsourced Accounting Team to deliver tailored financial services, manage client accounts, and drive operational excellence. Collaborate with clients and team members to enhance their...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.