Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Workday Administrator - HCM, Payroll & Intergrations
$110K *
Transform our Workday environment by optimizing HCM and Payroll systems, ensuring seamless integrations and compliance. Collaborate cross-functionally to enhance processes and drive strategic improvem...
2 weeks ago
$110K - $130K *
Elevate your career by leading structural and finite element analyses of turbomachinery components. Collaborate with engineers to develop methodologies, support design evaluations, and enhance analyti...
Yesterday
EHS Specialist- Environment, Health & Safety
$80K - $150K *
Shape the future of safety in a dynamic environment by developing and enhancing EHS programs. Collaborate across teams to foster a culture of safety and compliance, ensuring adherence to regulations w...
1 week ago
Senior Business Analyst - Claims module
$85K - $111K *
Advance your career by leading the Claims Domain for MMIS health care projects. Drive analysis, documentation, and quality processes while collaborating with clients and development teams to meet cust...
3 weeks ago
Manager, Data Protection Analysts (Americas)
$120K - $145K *
Shape the future of data protection by leading a high-performing team of analysts. Drive incident response, enhance security strategies, and collaborate with clients to mitigate risks in a fast-paced...
5 days ago
$160K - $200K *
Transform the communications landscape by building a dynamic team that drives brand relevance through strategic earned media, influencer relations, and corporate communications, ensuring a consumer-fi...
3 weeks ago
Mid-Enterprise Account Executive, East Coast
$200K - $250K *
Empower growth in the cybersecurity sector by driving sales, acquiring new accounts, and fostering strong customer relationships. Leverage your expertise to introduce innovative solutions and exceed s...
Reposted today
Senior Director, Patient Experience Center of Excellence
$156K - $202K *
Elevate patient experiences by leading strategic initiatives in governance, intelligence, and hospitality excellence. Drive performance improvement and operational consistency across healthcare servic...
1 week ago
$85K - $100K *
Join a dynamic team as you drive data integrity and enhance client reporting through Addepar. Leverage your analytical skills and operations experience to support private investment processes and coll...
1 week ago
Senior Site Reliability Engineer
$160K - $208K *
Transform our technology infrastructure by enhancing automation, troubleshooting issues, and fostering collaboration. Bring your expertise to support a scalable infrastructure platform that manages di...
Reposted today
$95K - $115K *
Elevate the Managed Services team by leading specialists in review response, social media, and listings management. Drive operational excellence, client satisfaction, and revenue growth while ensuring...
Today
$110K - $130K *
Partner with us to drive transformative healthcare solutions by managing key accounts, fostering relationships, and ensuring measurable outcomes. Your expertise will enhance provider partnerships and...
1 week ago
National Account Director, Enterprise Access
$240K - $269K *
Advance your career by leading national account strategies in oncology, fostering relationships with health plans and PBMs. Drive coverage, reimbursement, and adoption initiatives while collaborating...
2 weeks ago
Finance Consultant, Deltek Vision/Vantagepoint
$100K - $130K *
Unlock potential by partnering with clients to deliver tailored finance solutions, optimizing system performance, and enhancing project management activities. Leverage your expertise to drive client s...
Yesterday
Senior Project Manager (Neuroscience)
$122K *
Elevate your career by managing global projects in Neuroscience, ensuring compliance, budget adherence, and successful collaboration across cross-functional teams to drive milestone achievement and en...
Reposted 4 weeks ago
Analyst I, Falcon Complete GovCloud (Hybrid, St. Louis)
$85K - $120K *
Unlock potential in cybersecurity by engaging in real-time incident response and threat detection for government organizations. Develop your skills in a compliance-driven environment while protecting...
Yesterday
$210K - $250K *
Champion high-quality inpatient care as a Board-Certified Internal Medicine Hospitalist. Enjoy a 7-on/7-off schedule, competitive compensation, and a collaborative environment focused on clinical exce...
1 week ago
Associate Director Epidemiology
$156K - $234K *
Lead strategic epidemiological initiatives in oncology and neurology, driving evidence generation and operational execution for non-interventional studies. Collaborate cross-functionally to support cl...
4 days ago
Nurse Practitioner, HouseCalls - Clay and Jackson Counties, MO
$109K - $164K *
Transform healthcare delivery by conducting in-home assessments, improving member health outcomes through education and collaboration with primary care providers. Enjoy flexible scheduling and a suppo...
3 weeks ago
$95K - $115K *
Execute comprehensive project controls to ensure timely, budget-compliant project completion. Collaborate with teams to analyze financial data, manage forecasts, and report on project progress across...
2 weeks ago
$115K - $135K *
Drive your career forward by managing a diverse portfolio of high-net-worth clients, delivering expert tax preparation and advisory services while collaborating with financial advisors to maximize cli...
1 week ago
Associate Director, Client Engagement
$100K - $120K *
Manage a team of engagement managers to enhance operational effectiveness, drive project execution, and implement innovative solutions. Oversee financial performance and resource allocation while fost...
2 weeks ago
Senior Advisor, Budgeting & Resource Planning
$124K - $153K *
Transform financial management practices by leading budgeting, forecasting, and resource allocation efforts. Collaborate with teams to enhance decision-making and optimize financial systems, ensuring...
1 week ago
Manager, Client Strategy & Operations
$100K - $120K *
Join a team that's focused on enhancing client delivery and relationship growth. Drive data-driven strategies and cross-functional collaboration to optimize post-sale operations, ensuring exceptional...
Reposted 2 weeks ago
Senior Director for Advancement - Health System
$81K - $100K *
Transform your career by leading strategic fundraising initiatives, building relationships, and securing major gifts to support education, research, and patient care within a collaborative health syst...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.