Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Healthcare Analyst Jobs in Missouri

Sort By: Relevance

$111K *

Unlock potential by leading Clinical Documentation Integrity operations, enhancing physician engagement, and driving performance improvement. Collaborate with diverse teams to ensure compliance and op...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$71K - $100K *

Drive strategic initiatives by analyzing market trends and performance metrics. Collaborate with cross-functional teams to develop business cases and forecasts, ensuring data integrity and delivering...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Join a team that's dedicated to safeguarding sensitive health information while enhancing security across cloud and application environments. As a Senior Security Engineer, you'll design and implement...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $215K *

Lead a dynamic team to innovate and enhance healthcare technology solutions. Drive cross-functional collaboration, mentor engineers, and ensure high-quality software delivery while aligning with strat...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$90K - $105K *

Drive the migration of patient data within a healthcare IT modernization program. Oversee planning, execution, and reporting for your workstream, ensuring alignment with stakeholders and delivery of h...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Business Services

$120K - $155K *

Empower patients by delivering compassionate, patient-centered palliative care through virtual consultations. Collaborate with a dynamic team to enhance quality of life for members with complex needs...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$83K - $222K *

Transform data engineering practices by designing robust data pipelines and models. Collaborate with cross-functional teams to enhance analytics capabilities and ensure data quality, governance, and p...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$113K - $197K *

Lead regulatory and compliance oversight for Operations, ensuring accuracy and efficiency. Collaborate with enterprise partners to enhance operational processes, implement automation, and drive contin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$98K - $115K *

Lead independent assessments to evaluate and enhance the Bank's risk management practices, ensuring compliance with evolving regulatory standards while guiding a team of analysts in a dynamic environm...

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Take ownership of revenue modeling and forecasting, leveraging AI to automate processes and enhance reporting accuracy. Collaborate across functions to drive financial insights and support strategic d...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Business Services

$103K - $171K *

Elevate security compliance by collaborating with cross-functional teams to maintain accurate documentation and support federal compliance initiatives, ensuring systems meet evolving cybersecurity sta...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$235K - $270K *

Unlock potential by leading actuarial strategy and health economic analyses. Collaborate with cross-functional teams to enhance value propositions and drive commercial growth while translating complex...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$87K - $161K *

Optimize automation and AI capabilities within Security Defense Technologies. Collaborate with teams to design AI solutions, enhance Kubernetes operations, and implement secure development practices t...

Missouri, USRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$86K - $138K *

Empower your career by leading business analysis efforts, collaborating with stakeholders to enhance system applications, and driving innovative solutions that improve operational efficiency and user...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Pioneer in radiology innovation by enhancing clinical value and technology. Join a forward-thinking team that prioritizes high-quality patient care while driving improvements in service and operationa...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$101K - $145K *

Lead the charge in leveraging advanced data science techniques to solve complex business challenges, mentor junior team members, and drive effective risk management through innovative algorithms and d...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Drive analytical excellence by auditing freight contracts and invoices, ensuring compliance and accuracy. Collaborate with teams to enhance audit processes and mentor junior analysts, contributing to...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$120K - $165K *

Join a dynamic team as a Managing Consultant, driving innovative solutions in Revenue Integrity. Oversee engagements, enhance client relationships, and lead project teams to optimize financial perform...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$69K - $101K *

Lead the charge in holistic clinical care management, enhancing health outcomes through comprehensive assessments, care planning, and coordination for diverse member populations with complex needs...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $105K *

Unlock potential by supporting compensation programs through analysis, reporting, and administration. Collaborate with HR and finance teams to ensure accurate employee compensation data and streamline...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Transform financial operations by leveraging Workday expertise to enhance reporting, payroll, and planning processes. Collaborate with cross-functional teams to deliver scalable solutions and drive co...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$78K - $113K *

Innovate healthcare fraud prevention by leading complex investigations, evaluating medical necessity, and collaborating with regulatory agencies to ensure quality member care and safeguard plan assets...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$78K - $113K *

Unlock potential by leading complex investigations into healthcare fraud, waste, and abuse. Collaborate with regulatory agencies and internal teams to ensure compliance and safeguard member care while...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$172K - $202K *

Innovate within identity and access management by providing expert insights and strategies to clients on best practices in identity governance, privileged access, and AI tools, enhancing cybersecurity...

RemoteRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Business Services

$80K - $95K *

Transform your career by driving sales growth in a dynamic healthcare market. Leverage your consultative selling skills to build relationships, develop new business, and enhance client engagement in a...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.