Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$142K - $195K *

Join a team that's driving digital transformation by designing scalable solutions and leading architecture efforts. Leverage your expertise to enhance client experiences and deliver measurable outcome...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$142K - $195K *

Unlock potential by leading digital transformation initiatives through scalable solutions and strategic architecture. Collaborate across teams to enhance client experiences and drive measurable outcom...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$70K - $105K *

Elevate client relationships by managing strategic accounts, coordinating project execution, and driving client engagement. Contribute to financial management and proactive growth opportunities while...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive impactful solutions as you lead integration efforts, enhancing user experiences through collaboration and innovation while managing multiple complex projects and mentoring junior engineers...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$140K - $185K *

Unlock the power of enterprise data as you design and implement Master Data Management solutions that enhance healthcare operations, drive analytics, and enable AI-driven decision-making with trusted...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$115K - $175K *

Lead the charge in transforming client objectives into actionable solutions by bridging business needs with technical requirements. Engage in hands-on delivery, ensuring effective implementation and a...

2 days ago

  •   5 - 7 years exp.  •   Business Services

$225K - $265K *

Transform healthcare interoperability by leading product strategy and market growth. Leverage deep industry insights to enhance payer-provider collaboration, drive operational excellence, and oversee...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$215K - $292K *

Transform enterprise architecture by defining standards and governance for data, AI, and integration solutions in a regulated life sciences environment. Lead a team while collaborating across technolo...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$101K - $197K *

Lead the development and execution of strategic sales initiatives to enhance market share and client relationships within designated therapeutic areas, ensuring alignment with organizational goals and...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$129K - $162K *

Empower healthcare transformation by providing legal support in payor contracting. Collaborate with cross-functional teams to negotiate, draft, and manage contracts, ensuring compliance with regulator...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Champion patient safety by monitoring neuromuscular function during surgeries. Collaborate with surgical teams to ensure optimal outcomes through real-time data analysis and communication, making a si...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Join a team that's dedicated to ensuring financial integrity and compliance. In this hands-on role, you'll manage revenue recognition and accounting processes, collaborating across departments to supp...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Elevate database performance and security by managing SQL Server instances, optimizing ETL processes, and leading cloud migration strategies while collaborating with cross-functional teams to enhance...

Reposted today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Join a team that's redefining clinical workflows by serving as a trusted clinical voice, collaborating across departments to enhance product development and ensure successful implementation of cardiov...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $138K *

Elevate your career by delivering expert clinical education and training. Drive customer success through hands-on support and relationship building, optimizing product adoption and enhancing patient c...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Business Services

$92K - $138K *

Help us enhance clinical education by delivering expert training and support to healthcare professionals. Drive product adoption and optimize user competencies while fostering strong relationships wit...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$210K - $286K *

Champion strategic legal guidance on employment matters, managing litigation and compliance while collaborating with leadership to mitigate risks and support organizational objectives in a complex hea...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$142K - $213K *

Pioneer innovative clinical strategies by leading cross-functional teams in the design and execution of clinical studies, ensuring effective development plans and therapeutic area strategies for impac...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $115K *

Lead the execution and optimization of email and SMS marketing channels, enhancing performance and compliance. Own end-to-end processes, from creative testing to analytics, while collaborating cross-f...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $245K *

Join a team that's dedicated to providing expert employment counsel across a global workforce. You'll partner with business leaders to navigate complex employment issues, ensuring sound legal advice t...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$170K - $185K *

Champion innovative software solutions by leading complex projects, mentoring engineers, and driving technical excellence across teams. Collaborate on strategic initiatives to enhance reliability and...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $125K *

Join a team that's advancing genomic research by developing NGS workflows to explore genome instability in HR-deficient cancers, collaborating with academic and biopharma partners to translate finding...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $110K *

Discover your potential by supporting data-driven decision-making as you develop and implement advanced statistical and machine learning models. Collaborate with stakeholders and enhance your skills i...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$135K - $173K *

Advance your career as a valued member of a multidisciplinary team, providing specialized research procedures and patient care across diverse medical settings, while leveraging your skills and experie...

1 month ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$88K - $115K *

Unlock your potential in a pivotal integration role, ensuring customer success through seamless technical setups, collaboration across teams, and enhancement of integration performance for optimal sat...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.