Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$130K - $145K *

Elevate revenue cycle management by analyzing workflows, optimizing processes, and driving strategic improvements. Collaborate across teams to enhance billing accuracy and maximize collections in a fu...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$117K - $171K *

Join our scientific computing team to enhance the researcher experience for a high-performance computing platform, driving user engagement, training, and support for data-intensive biomedical research...

Yesterday

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$118K - $196K *

Lead the charge in developing and executing drug formulary strategies, ensuring compliance with regulations while collaborating with cross-functional teams to enhance pharmacy utilization management a...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$133K - $192K *

Lead the charge in product management within AI-driven healthcare, collaborating with diverse teams to optimize clinical modeling and simulation, ensuring impactful delivery and strategic alignment wi...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $205K *

Join a team that's transforming payroll solutions by leading Workday Payroll implementations, optimizing processes, and mentoring junior consultants to enhance client efficiency and satisfaction...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$74K - $100K *

Support the administration of sales compensation programs through accurate commission calculations, reporting, and process improvement initiatives. Collaborate effectively with Finance, Sales, and HR...

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$115K - $192K *

Empower strategic relationships with health & benefits consultants to enhance awareness and adoption of our innovative solutions. Drive engagement and collaboration to influence employer decisions and...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $155K *

Empower innovation by managing Microsoft 365 services and AI solutions, ensuring seamless end-user support and infrastructure. Drive productivity through technology while maintaining security and comp...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Champion data-driven innovation by leading advanced predictive analytics and modeling initiatives. Collaborate cross-functionally to enhance strategic decision-making and drive business growth with im...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$83K - $99K *

Discover and enhance patient care by providing comprehensive dental hygiene services, including screenings, cleanings, and education, while collaborating with the dental team to ensure optimal patient...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $235K *

Champion innovative compensation strategies that align with business goals, attract top talent, and drive organizational growth. Collaborate with senior leaders to navigate complex compensation challe...

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$109K - $174K *

Join a team that's advancing next-generation cell therapies by designing and executing in vitro assays to select CAR-T candidates, driving data-driven decisions in a dynamic, collaborative environment...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$144K - $288K *

Drive innovative digital product strategies for chronic condition management, leading cross-functional teams to enhance patient care pathways and optimize outcomes through technology integration and o...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$105K - $120K *

Lead high-quality hospice care by managing clinical operations, coordinating patient services, and mentoring staff. Ensure compliance with regulations while fostering a compassionate environment for t...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Join us to oversee the Clinical Resource department, managing case management and social work staff. Drive operational excellence, enhance discharge planning, and foster continuous education while ens...

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $110K *

Drive client success by managing small to medium accounts, enhancing engagement, and leveraging data insights to improve health outcomes and revenue growth. Collaborate with teams to implement solutio...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$84K - $107K *

Join a dedicated team to deliver comprehensive home health nursing services, managing patient care through assessments, interventions, and support. Collaborate with healthcare professionals to ensure...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $210K *

Join a team that's driving innovation in data science through rigorous analysis, algorithm development, and collaboration to enhance AI and machine learning systems for national security applications...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$148K - $222K *

Pioneer advanced analytics strategies to optimize omnichannel investments, translating global performance data into actionable insights. Collaborate with cross-functional teams to drive measurable com...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Unlock potential by driving BioPharma partnership success through innovative liquid biopsy solutions, enhancing clinical trial designs, and fostering key relationships in oncology precision medicine...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$145K - $234K *

Help us shape the future of third-party cybersecurity risk management by leading comprehensive assessments, identifying control gaps, and enhancing compliance practices in a dynamic, regulated environ...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$142K - $195K *

Lead the design and implementation of ForgeRock-based CIAM/XIAM solutions. Drive architecture strategy, ensure compliance, and mentor teams on best practices to enable scalable identity management sol...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $105K *

Empower a data-driven culture by analyzing and optimizing business processes. Leverage data insights to drive impactful decisions, enhance stakeholder outcomes, and support the development of a compre...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Unlock potential by providing in-home occupational therapy services, evaluating safety, assessing functional needs, and implementing personalized treatment plans to enhance patient independence and qu...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$161K - $210K *

Elevate workforce management by leading recruitment, onboarding, and performance strategies. Drive clinician readiness and productivity while ensuring quality care through data-driven decision-making...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.