Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$117K - $161K *

Join a team that's redefining member engagement through advanced analytics and strategic leadership. Drive analytics strategy, mentor engineers, and enhance conversational experiences across innovativ...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$78K - $88K *

Join us to perform actuarial analyses and support healthcare consulting projects. Collaborate with multidisciplinary teams to develop insights, maintain models, and communicate findings effectively wh...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$90K - $110K *

Grow your career with us as you shape critical patient data flows, ensuring seamless integration of ADT/Cadence/Prelude systems. Collaborate across teams, mentoring colleagues while navigating the com...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a team that's redefining software engineering by integrating AI tools to accelerate the development process. Transform requirements into reliable solutions while ensuring quality, security, and m...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$97K - $125K *

Drive impactful change by analyzing user needs and defining requirements for clinical applications. Collaborate with diverse teams to enhance electronic health record systems, ensuring effective docum...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$174K - $374K *

Lead the charge in clinical oversight and mentorship, driving innovative medical solutions across diverse programs. Collaborate with cross-functional teams to ensure evidence-based decision-making and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $155K *

Empower financial transformation with post-merger integration strategies. Collaborate with clients to enhance accounting processes and optimize integration initiatives for growth-focused businesses af...

3 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$122K - $176K *

Elevate bioanalytical and biomarker operations by managing outsourcing efforts, ensuring quality deliverables, and collaborating with stakeholders throughout clinical and preclinical studies for impac...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Advance business processes by analyzing requirements and defining system objectives. Collaborate with IT to enhance applications and support testing efforts for small to moderate projects, ensuring al...

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Innovate business processes by analyzing requirements and defining system objectives. Collaborate across IT to enhance applications and support testing efforts, ensuring effective solutions for small...

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Lead and empower nursing teams to deliver high-quality, patient-centered care while managing resources and ensuring compliance. Drive operational excellence and enhance patient satisfaction in a colla...

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$87K - $153K *

Unlock potential by assessing and optimizing AWS environments, identifying gaps, and recommending architecture improvements. Collaborate with technical stakeholders to enhance cloud infrastructure and...

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Empower nursing excellence by designing and implementing comprehensive education programs across diverse clinical areas, enhancing professional development through collaboration and innovative teachin...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Champion seamless communication by managing VoIP and telephony systems, ensuring optimal performance and user satisfaction. Collaborate across departments to analyze data, enhance workflows, and uphol...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$83K - $112K *

Support large-scale research initiatives by managing operations, budgets, and partnerships. Oversee project teams, ensure compliance, and contribute to data analysis and publications, driving innovati...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Tackle security challenges by spearheading vulnerability and attack surface management. You'll build crucial programs, refine risk assessments, and ensure operational excellence in safeguarding sensit...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$61K - $98K *

Transform the landscape of risk management by overseeing collections and funding returns, analyzing transaction patterns, and collaborating with teams to resolve complex cases while driving process im...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $110K *

Drive sales and develop relationships with financial advisors across various channels to enhance market share and revenue for investment products, while collaborating with team members to leverage dat...

RemoteRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $105K *

Analyze data and create actionable insights to enhance business intelligence. Engage in SQL, Python, and data visualization to maintain dashboards, support modeling, and drive improvements in efficien...

United StatesRemote

Reposted 1 month ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$80K - $95K *

Lead the charge in providing information assurance support to ensure security compliance for systems at Hanscom AFB, managing risks and aiding in certification processes to safeguard vital data and in...

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $145K *

Accelerate progress at a crucial leadership role shaping enterprise data strategies. Collaborate with global teams to define roadmaps that turn fragmented data into strategic insights for R&D, Medical...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

The Director of Government Reimbursement will serve in a consultancy capacity, advising large health systems on managing and optimizing healthcare reimbursement processes, particularly focusing on Med...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$130K - $178K *

Transform procurement strategies by leading complex sourcing initiatives, collaborating with cross-functional teams, and driving cost-effective solutions to enhance operational efficiency and supplier...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$135K - $185K *

Transform data into actionable insights by enhancing financial models, optimizing sales performance, and driving operational efficiencies. Collaborate with cross-functional teams to support strategic...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Technical Services

$100K - $120K *

Join a team that's dedicated to enhancing clinical operations through strategic site identification and management. Leverage your expertise to build relationships, track project timelines, and contrib...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.