Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$107K - $147K *

Champion the integration of business needs and technical solutions, driving product delivery through collaboration with stakeholders. Leverage your expertise to translate requirements into actionable...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Empower life sciences innovation by evaluating AI model outputs, ensuring quality and accuracy. Collaborate with cross-functional teams to enhance predictive analytics and insights, bridging clinical...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive your career with a senior role that leverages healthcare expertise to support sales processes, lead solution demonstrations, and collaborate with teams to enhance customer success and revenue gr...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $180K *

Accelerate pharmacy analytics innovation by leading strategic design and execution of data-driven solutions that enhance pharmacy benefit performance and client engagement, while guiding a dedicated a...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $130K *

Lead the charge in enhancing member care as you coach and develop clinical teams, oversee daily operations, and ensure compliance with regulatory standards while driving quality improvements and opera...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Join a dynamic team to analyze processes and implement Salesforce solutions. Collaborate with stakeholders, developers, and teams to enhance system functionality and ensure user alignment for impactfu...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Staffing

$100K - $140K *

Engage in the design and deployment of Epic integrations, collaborating across healthcare IT teams to enhance ordering and data workflows, ensuring effective application support and training for end-u...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$73K - $130K *

Drive the acquisition and usability of clinical data to enhance healthcare outcomes. Collaborate with diverse teams to analyze data gaps, implement integrations, and optimize processes, ensuring timel...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$108K - $130K *

Unlock your potential by leading customer projects, ensuring seamless communication, and driving success in healthcare solutions. Collaborate with diverse teams to enhance client satisfaction and oper...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$173K - $245K *

Unlock insights through data analytics and experimentation to enhance credit risk management. Collaborate with cross-functional teams to optimize policies, monitor performance, and drive strategic gro...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Champion healthcare solutions by managing integrations and providing expert support. Drive projects and improve processes as a Senior Interface Analyst in a dynamic and innovative environment, ensurin...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by driving improvements in pricing data management, data quality, and asset class coverage. Collaborate within a dynamic, agile environment to optimize workflows and support enterpris...

1 month ago

  •   5 - 7 years exp.  •   Business Services

$110K - $183K *

Optimize health policy research by applying advanced quantitative methods to inform stakeholders. Collaborate on multidisciplinary teams to evaluate health care markets, coverage, and costs, deliverin...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $100K *

Engineer AI-driven data solutions by designing, deploying, and maintaining scalable systems. Collaborate with stakeholders to transform business needs into effective machine learning applications and...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$95K - $115K *

Empower our mission by leading IT audits that assess risk and enhance controls. Collaborate across teams to ensure compliance and operational effectiveness while mentoring fellow auditors and deliveri...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Lead the charge in implementing and supporting data analytics initiatives across multiple business units, enhancing productivity through advanced AI solutions and collaborative business intelligence e...

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$122K - $177K *

Advance your nursing career by managing complex case management and er duties. Collaborate with interdisciplinary teams to improve patient outcomes, streamline discharges, and enhance operational perf...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$64K - $120K *

Empower clients by delivering expert employee benefits solutions. Collaborate with teams to enhance client strategies, manage projects, and ensure compliance while fostering strong vendor relationship...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$64K - $120K *

Join a dynamic team as you provide expert employee benefits consulting, collaborating with clients and vendors to enhance their insurance strategies and ensure compliance while delivering exceptional...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Empower decision-making by utilizing data-driven insights to enhance operations, supporting growth through statistical modeling and AI techniques while maintaining compliance in a complex regulatory e...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$89K - $121K *

Transform patient care by overseeing complex care management and transitions. Collaborate with interdisciplinary teams to ensure effective, patient-centered approaches, optimizing health outcomes and...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $110K *

Solve complex production challenges and ensure system stability as a key technical support resource. Collaborate cross-functionally to enhance customer satisfaction through effective incident manageme...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$113K - $226K *

Lead the charge in optimizing healthcare processes by bridging strategy and execution. Collaborate with teams to enhance coding workflows, drive change management, and ensure alignment with strategic...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$79K - $125K *

Lead the charge in enhancing Employer Health Solutions products, driving market competitiveness through collaboration, strategic analysis, and innovative development. Support regulatory compliance and...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$77K - $116K *

Unlock your potential as an Actuarial Analyst II, driving impactful analyses for Medicare Advantage pricing and financial performance. Collaborate with cross-functional teams to identify trends and en...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.