Explore $100K+ Jobs in Maine

Discover professional opportunities across Maine with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re looking to advance in your current field or take the next step in your career, explore openings across the state and find positions that match your experience and goals.

Professional opportunities across Maine

Maine’s economy includes healthcare, financial services, technology, manufacturing, education, energy, and other professional fields. High-paying roles may be available in Portland and other communities throughout the state, including remote and hybrid opportunities. Job availability and compensation vary by employer, location, and experience.

Find a role that fits your experience

Use Ladders to explore senior-level and experienced professional positions. Review each listing for salary details, responsibilities, required qualifications, and work arrangements. Set up a focused search by job title, industry, or location to identify opportunities aligned with your expertise.

Take the next step in your Maine job search

Build a strong application by highlighting measurable accomplishments, relevant leadership experience, and specialized skills. Keep your profile and resume current, and check back regularly for new Maine jobs paying $100,000 or more.

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$105K - $130K *

Shape the future of analytics by leading reporting initiatives and managing client relationships. Drive implementation strategies, gather requirements, and deliver impactful dashboard solutions using...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Transform clinical operations by leading a dynamic team, ensuring high-quality trial management, and driving innovation through technology and AI solutions. Your strategic oversight will enhance perfo...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$200K - $270K *

Join a team that's redefining biostatistics in clinical development. You will lead statistical strategy across multiple therapeutic areas, ensuring excellence in design, analysis, and reporting while...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$83K - $114K *

Grow your career with a dynamic team delivering compassionate dialysis care. Utilize your nursing expertise in a fast-paced outpatient setting, ensuring patient safety and comfort while collaborating...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$89K - $122K *

Empower patients through compassionate care in a dynamic outpatient dialysis setting. Collaborate with a dedicated team to monitor treatment plans, educate families, and build lasting relationships wh...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$83K - $114K *

Grow your career with a dynamic team delivering compassionate dialysis care. Utilize your nursing skills in a fast-paced outpatient setting, ensuring patient safety and comfort while collaborating wit...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $108K *

Join a team that's dedicated to providing high-quality outpatient dialysis care. You'll collaborate with clinical professionals, manage patient treatments, and educate families—all while fostering las...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$81K - $114K *

Transform patient care by delivering compassionate dialysis services in a dynamic outpatient setting. Collaborate with a skilled team to ensure safety and comfort while utilizing critical thinking to...

Weeks Mills, MEIn-Person

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$81K - $110K *

Champion quality care for ESRD patients by coordinating services, tracking outcomes, and ensuring safety in a supportive team environment. Leverage your nursing skills to build strong relationships in...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Unlock AI-driven engineering transformation by collaborating with clients to enhance SDLC processes. Drive measurable improvements in delivery speed and quality through innovative solutions and hands...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$116K - $193K *

Lead the charge in defining and executing the product strategy for AI and analytics, driving innovation across pharmacy management platforms. Collaborate with cross-functional teams to deliver scalabl...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$200K - $230K *

Champion a transformative member software experience, guiding strategy and design across the care journey. Leverage data and user insights to drive impactful solutions in a complex healthcare landscap...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$274K - $371K *

Elevate patient care through innovative clinical strategies in obesity and cardiometabolic development. Collaborate across teams to design and implement late-phase studies, ensuring alignment with glo...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$105K - $150K *

Inspire impactful change by leading complex federal digital services programs. Oversee strategy, execution, and customer relationships while managing multidisciplinary teams to deliver high-quality te...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$75K - $158K *

Champion operational excellence by managing the Avantra platform for SAP, ensuring secure, efficient monitoring and automation across diverse environments while collaborating with cross-functional tea...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Lead the charge in enhancing software quality and reliability through automation. Collaborate with cross-functional teams to troubleshoot complex issues while mentoring others to achieve excellence in...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $216K *

Transform program administration for a large federal services initiative, overseeing workforce planning, financial operations, and compliance. Collaborate with diverse teams to enhance operational eff...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$95K - $115K *

Empower our finance team by overseeing accounting operations, ensuring compliance, and enhancing financial reporting. Lead month-end close activities and mentor team members in a dynamic, multi-entity...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$86K - $118K *

Innovate content design strategies to enhance user experiences across digital platforms. Collaborate with cross-functional teams to simplify complex healthcare information, ensuring clarity and access...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$107K - $180K *

Join a team that's redefining API integration! Leverage your technical expertise to guide partners through the integration lifecycle, ensuring seamless onboarding and successful implementations while...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$120K - $145K *

Drive your career with a pivotal role in shaping product strategy and delivery, enhancing member experiences in healthcare. Collaborate across teams to define problems, prioritize outcomes, and levera...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Join a team that's dedicated to ensuring the quality and safety of clinical trials. As a Senior Clinical Research Associate, you'll manage site relationships, oversee monitoring activities, and contri...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a dynamic team to lead the creation of impactful scientific content, enhancing medical education and patient outcomes. Collaborate cross-functionally, mentor writers, and drive excellence in heal...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$73K - $100K *

Empower program success by managing daily operations and documentation for a key transformation initiative, coordinating across teams, maintaining accurate records, and supporting financial and admini...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$126K - $173K *

Champion the development of Provider Direct Connect capabilities, driving product vision and strategy while collaborating with cross-functional teams to enhance provider engagement and deliver scalabl...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Maine?question toggle

    Listings may include experienced and senior professional roles in areas such as healthcare, technology, finance, manufacturing, education, and management. Available positions depend on current employer hiring needs.

  • Are these Maine jobs vetted?question toggle

    Ladders focuses on vetted professional job opportunities that pay $100,000 or more. Review each listing for its specific employer, qualifications, compensation, and application details.

  • Where in Maine can I search for high-paying jobs?question toggle

    Search statewide, including Portland and other Maine communities. You can also check listings for remote or hybrid arrangements where available.

  • Do all Maine jobs listed pay at least $100,000?question toggle

    Ladders specializes in professional jobs paying $100,000 or more. Confirm the salary information and compensation terms on the individual job listing.

  • How can I improve my chances of finding a high-paying job in Maine?question toggle

    Tailor your resume to each role, emphasize relevant results and leadership experience, and use job title, industry, and location filters to focus your search. Check listings regularly for new opportunities.