Explore $100K+ Jobs in Maine

Discover professional opportunities across Maine with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re looking to advance in your current field or take the next step in your career, explore openings across the state and find positions that match your experience and goals.

Professional opportunities across Maine

Maine’s economy includes healthcare, financial services, technology, manufacturing, education, energy, and other professional fields. High-paying roles may be available in Portland and other communities throughout the state, including remote and hybrid opportunities. Job availability and compensation vary by employer, location, and experience.

Find a role that fits your experience

Use Ladders to explore senior-level and experienced professional positions. Review each listing for salary details, responsibilities, required qualifications, and work arrangements. Set up a focused search by job title, industry, or location to identify opportunities aligned with your expertise.

Take the next step in your Maine job search

Build a strong application by highlighting measurable accomplishments, relevant leadership experience, and specialized skills. Keep your profile and resume current, and check back regularly for new Maine jobs paying $100,000 or more.

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$104K - $166K *

Join a team that's dedicated to enhancing cybersecurity operations by monitoring, analyzing, and responding to security incidents. Leverage your expertise to protect critical systems and mentor junior...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$95K - $115K *

Unlock potential by bridging business and technical teams to define and implement master data management and governance solutions, ensuring data quality and compliance across the organization...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$74K - $98K *

Elevate quality operations by leading corrective action plans (CAPs) for regulatory compliance. Collaborate with cross-functional teams to drive accountability, resolve barriers, and ensure sustained...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $120K *

Analyze and enhance business processes across the services lifecycle. Develop reporting solutions and dashboards to drive informed decisions, improve revenue predictability, and support stakeholders i...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$90K - $95K *

Champion the analysis of Low-Income Housing Tax Credit projects, leveraging strong financial acumen to prepare investment models and reports. Collaborate with developers and manage multiple assignment...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$77K - $115K *

Join a team that's driving innovation in IT solutions by leveraging your expertise in systems analysis and functional design. Collaborate with cross-functional teams to enhance business processes and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $85K *

Grow your career with a dynamic team focused on client success, managing relationships, and delivering tailored solutions. Drive satisfaction and retention while collaborating across departments to en...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$89K - $150K *

Optimize sales operations by managing forecasting and data analytics to enhance revenue delivery. Collaborate with cross-functional teams to ensure data accuracy and support sales processes, enabling...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K *

Shape the future of enterprise data engineering by developing scalable data pipelines and integrating AI capabilities. Drive modernization efforts and enhance operational efficiency through automation...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$75K - $158K *

Drive enterprise-level technical solutions by analyzing system needs, coordinating design activities, and ensuring compliance with governance processes. Leverage your expertise to enhance performance...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $175K *

Shape the future of client partnerships by driving strategic growth and success for large enterprise organizations. Collaborate with cross-functional teams to deliver exceptional value and measurable...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to enhancing healthcare quality through thorough medical claims audits. Leverage your nursing expertise in a dynamic remote environment, collaborating with experienced aud...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$142K - $161K *

Join us to ensure the highest quality standards for our FDA-cleared AI clinical platform. Collaborate across teams to drive software design quality, manage regulatory compliance, and enhance post-mark...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Elevate your career by preparing and analyzing complex Medicaid cost reports, ensuring compliance with regulations, and leading a team of accountants in a remote setting. Drive process improvements an...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$90K - $110K *

Deliver excellence in clinical research by managing monitoring activities, ensuring site compliance, and fostering strong relationships with investigators. Drive study integrity and patient safety whi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$71K - $97K *

Pioneer the integration of comprehensive assessments and discharge planning to ensure coordinated, quality care for admitted members, enhancing health outcomes and optimizing member wellness through c...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Drive statistical excellence in oncology clinical trials, ensuring accuracy and quality of deliverables while collaborating with diverse teams to support impactful research across various health secto...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$129K - $177K *

Join a team that's shaping innovative pricing strategies for Medicare Advantage products. Collaborate cross-functionally to analyze market data, establish financial metrics, and drive profitable growt...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Drive customer success by managing relationships and ensuring product adoption. Collaborate with teams to mitigate risks, enhance customer experience, and create growth opportunities while mentoring p...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$68K - $105K *

Shape the future of Information Security by assisting in the design, development, and implementation of ISRM Infrastructure systems. Collaborate with teams to ensure compliance, analyze systems perfor...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$164K - $205K *

Lead the design and analysis of clinical validation studies, ensuring regulatory compliance and driving innovative research in molecular diagnostics. Collaborate with cross-functional teams to enhance...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate your career by driving ERP innovation and optimization. Collaborate with stakeholders to enhance Workday and corporate applications, ensuring seamless integration and maximum value delivery ac...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $158K *

Drive strategies to enhance customer engagement and retention for pharmacy services. Collaborate with cross-functional teams to optimize member experiences, increase auto-refill adoption, and boost pr...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$103K - $140K *

Shape the future of supply chain analytics by leveraging AI and data science expertise to develop innovative solutions that enhance decision-making and user productivity across the organization...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a team that's dedicated to enhancing security operations through proactive monitoring, incident response, and client engagement. This role offers the chance to lead investigations and improve sec...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Maine?question toggle

    Listings may include experienced and senior professional roles in areas such as healthcare, technology, finance, manufacturing, education, and management. Available positions depend on current employer hiring needs.

  • Are these Maine jobs vetted?question toggle

    Ladders focuses on vetted professional job opportunities that pay $100,000 or more. Review each listing for its specific employer, qualifications, compensation, and application details.

  • Where in Maine can I search for high-paying jobs?question toggle

    Search statewide, including Portland and other Maine communities. You can also check listings for remote or hybrid arrangements where available.

  • Do all Maine jobs listed pay at least $100,000?question toggle

    Ladders specializes in professional jobs paying $100,000 or more. Confirm the salary information and compensation terms on the individual job listing.

  • How can I improve my chances of finding a high-paying job in Maine?question toggle

    Tailor your resume to each role, emphasize relevant results and leadership experience, and use job title, industry, and location filters to focus your search. Check listings regularly for new opportunities.