Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.
Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.
Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.
Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.
Associate Director, Talent Analytics & Assessment Science
$132K - $193K *
Unlock potential by leading the enterprise employee listening strategy, enhancing assessment science, and applying analytics to drive data-informed talent decisions. Collaborate with cross-functional...
1 week ago
IT Infrastructure Design Engineer
$100K - $120K *
Join a team that's dedicated to innovation and excellence, driving projects from concept to completion. Collaborate with cross-functional teams to enhance product development and ensure quality standa...
2 weeks ago
$133K - $180K *
Join a team that's redefining member experiences by architecting optimal journeys, bridging operational execution with strategic vision to enhance engagement and satisfaction across all touchpoints...
1 month ago
Director of Insurance Plan Management
$120K - $150K *
Transform the landscape of dental negotiations by leading strategic partnerships with payers, optimizing contracts, and driving revenue growth through data-driven insights and collaborative execution...
1 week ago
AI & GenAI Data Scientist-Senior Associate
$77K - $202K *
Champion advanced analytics and AI solutions by transforming complex data into actionable insights, guiding junior team members, and driving data-driven decision-making within a collaborative environm...
1 week ago
$82K - $108K *
Empower your career by managing and advancing clinical research initiatives. Collaborate with leadership and stakeholders to facilitate trials and grants while ensuring compliance and oversight, foste...
1 month ago
$98K - $115K *
Unlock potential by leading financial and administrative operations at a premier institute. Collaborate with faculty and staff to drive strategic initiatives, manage complex budgets, and enhance resea...
2 weeks ago
$80K - $100K *
Join a team that's dedicated to providing compassionate end-of-life care. As a Hospice Admissions Nurse, you'll assess patient eligibility, guide families through the admissions process, and collabora...
Yesterday
Life Sciences Data Management, Lead (MDM/DGov)
$134K - $265K *
Lead the charge in transforming Life Sciences commercial operations through innovative Customer MDM and AI solutions. Drive client engagements, build high-performing teams, and ensure data governance...
2 days ago
Care Manager Registered Nurse - Field (Central Illinois -Peoria)
$66K - $142K *
Champion patient care by coordinating case management for dual eligible populations. Utilize critical thinking to enhance healthcare outcomes through effective communication and collaboration with mem...
3 weeks ago
Care Manager Registered Nurse - Field (Central Illinois -Peoria)
$66K - $142K *
Join our team to elevate patient care for dual eligible populations. Utilize your clinical expertise to facilitate healthcare outcomes, collaborating with members and providers to address complex heal...
3 weeks ago
$168K - $231K *
Join a dynamic team to lead Nurse Case Managers, enhancing patient support and education throughout treatment journeys while ensuring compliance and quality in case management processes...
2 days ago
Project Manager, FEHRM Healthcare Technology Management - Interoperability
$95K - $125K *
Advance your career by coordinating healthcare technology integration across multiple VA sites. Leverage your project management skills to support the Federal Electronic Health Record Modernization pr...
3 weeks ago
Registered Nurse (RN) Cardiac Cath Lab
$79K - $118K *
Lead patient-centered care in a dynamic Cath Lab environment, ensuring safety and optimal experiences through skilled nursing practices and collaboration with healthcare teams...
4 days ago
$72K - $120K *
Join a team that's dedicated to enhancing cyber security infrastructure. As a Security Engineer I, you'll administer security services, conduct audits, and collaborate with analysts to protect against...
5 days ago
BI Analyst - Snowflake & QNXT | USC Only.
$80K - $95K *
Join a dynamic team as a BI Analyst, leveraging Snowflake and QNXT data to deliver actionable insights through advanced reporting and data visualization. Collaborate with stakeholders to drive data-dr...
1 week ago
Director, Competitive & Strategic Insights, Oncology Lead
$150K - $180K *
Transform the future of Oncology by driving global insights and competitive intelligence. Collaborate with cross-functional teams to influence asset development and strategic decisions, ensuring timel...
1 week ago
Director Information Services, Consumer Data Intelligence
$150K - $180K *
Lead the charge in transforming consumer data and intelligence capabilities, enhancing digital care through strategic governance, analytics, and cross-functional collaboration to drive insights and im...
Yesterday
Physical Therapist, Outpatient (Hyde Park Clinic)
$78K - $113K *
Lead patient-focused initiatives by conducting thorough assessments and developing personalized treatment plans to enhance mobility, relieve pain, and restore independence in an outpatient therapy env...
Reposted 2 weeks ago
Senior Director, Manufacturing Strategy
$170K - $200K *
Shape the future of global manufacturing strategy by leading initiatives that enhance operational efficiency, drive innovation, and align with organizational goals across the ME&C network, ensuring ro...
2 days ago
Vice President, Medicare Partnerships
$150K *
Lead the charge in driving Medicare partnerships, enhancing contract value, and achieving growth targets through strategic sales initiatives and relationship management with health plans...
2 weeks ago
Medical Nurse Practitioner/Physician Assistant
$110K - $120K *
Join a team that's dedicated to enhancing patient quality of life through compassionate care. Leverage your skills and autonomy in post-acute medicine while enjoying flexibility and competitive compen...
4 weeks ago
Clinical Research Nurse Coordinator
$80K - $95K *
Join a team that's dedicated to advancing clinical research through expert coordination and collaboration. As a Clinical Research Nurse Coordinator, you'll ensure compliance and support investigator t...
Yesterday
$82K - $100K *
Join a team that's dedicated to driving financial insights and strategic growth. You'll manage budgeting, forecasting, and reporting while collaborating with leadership to enhance decision-making and...
1 week ago
AI & GenAI Data Scientist-Director
$155K - $410K *
Transform data into strategic solutions as you lead AI projects that enhance business growth. Oversee client engagements, mentor teams, and implement cutting-edge data technologies to drive impactful...
Reposted 2 weeks ago
What types of $100,000+ jobs can I find in Illinois?
Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.
Are there high-paying jobs outside Chicago?
Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.
How can I find Illinois jobs that pay $100,000 or more?
Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.
Do Illinois job listings include remote or hybrid roles?
Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.