Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.
Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.
Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.
Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.
$88K - $105K *
Unlock potential by leveraging data science expertise to drive insights and solutions. Collaborate with stakeholders to evolve business capabilities through predictive modeling and innovative analytic...
Reposted 3 weeks ago
$110K - $120K *
Champion the development of high-quality program materials and deliverables, enhancing effectiveness in complex specialty markets. Collaborate with teams to ensure project success through strong manag...
3 days ago
Manager, Global EHS Compliance
$120K - $150K *
Lead the charge in developing and governing global EHS programs, ensuring compliance and minimizing risk. Drive strategic initiatives that enhance safety standards while fostering collaboration across...
3 weeks ago
Thought Leader Liaison Gastroenterology Midwest
$146K - $211K *
Grow your career with a dynamic role focused on KOL engagement and strategic collaboration in the gastroenterology field, driving insights and educational initiatives to elevate brand success in speci...
4 weeks ago
Director Financial Operations - Payment Integrity Operations
$138K - $238K *
Transform operational excellence by leading Payment Integrity initiatives, driving strategic alignment, and enhancing workforce effectiveness through data-driven insights and cross-functional collabor...
1 week ago
Senior Business Intelligence Analyst
$110K - $130K *
Champion data-driven decision-making by transforming insights into actionable reports and dashboards. Collaborate with cross-functional teams to enhance performance, optimize strategies, and drive bus...
2 weeks ago
$97K - $129K *
Optimize HVAC systems and enhance energy efficiency in complex projects. Collaborate with engineering teams to troubleshoot, implement control logic, and drive measurable performance improvements acro...
1 week ago
Insights Manager - Health & Life Sciences (Remote, US-based only)
$75K - $90K *
Unlock potential by leading data analysis and storytelling efforts, ensuring insights meet client needs. Collaborate with teams to deliver actionable reports and maintain high-quality standards throug...
2 days ago
$125K - $140K *
Optimize your career by managing enterprise-wide database environments, ensuring high availability, executing disaster recovery strategies, and supporting critical operations in a dynamic SaaS ecosyst...
Yesterday
$80K - $95K *
Advance business intelligence by leveraging data science techniques to develop predictive models and insights. Contribute to team success through collaboration and effective communication while drivin...
Reposted 3 weeks ago
Mid-Market Account Executive, Healthcare SaaS
$80K - $95K *
Join a team that's driving growth in mid-market healthcare by building relationships, managing a dynamic sales pipeline, and closing new business opportunities in a fast-paced SaaS environment...
1 week ago
Manager of Data Analysis for Lab Production Support, Extended-Hours Support (ExHS)
$140K - $175K *
Optimize data analytics support for lab production operations by leading a dedicated team in a dynamic environment. Drive innovation, ensure compliance, and enhance operational effectiveness while mak...
2 weeks ago
$115K - $130K *
Elevate operational efficiency by providing high-level administrative support to senior leadership, coordinating meetings, managing correspondence, and ensuring compliance with Navy directives while f...
2 weeks ago
Integrated Solution Strategy Director - Oncology
$135K - $160K *
Join us to lead Oncology integrated solutions, collaborating across teams to design and implement strategic, client-focused approaches. Shape impactful proposals that drive growth and enhance patient...
3 weeks ago
Analyst Sr Supply Chain -Transportation
$80K - $100K *
Analyze complex data and drive innovative solutions while providing guidance to team members. Collaborate with internal and external experts to improve processes and assist leadership in mitigating ri...
Reposted 3 weeks ago
Director STARS Strategy & Planning
$121K - $225K *
Champion the execution of Medicare Stars strategy, enhancing member experience through cross-functional collaboration and operational excellence. Lead strategic initiatives to achieve performance goal...
Yesterday
Account Development Manager II
$125K - $175K *
Transform client relationships by driving value and engagement in a fast-growing segment. Leverage product expertise to manage renewals and upsell opportunities while contributing to best practices wi...
3 weeks ago
Remote Program Analytics & Reporting Analyst (VA ESOM)
$90K - $120K *
Analyze data trends and support program oversight as a key team lead. Collaborate across multiple teams to enhance reporting and data quality, ensuring effective problem management and continuous impr...
5 days ago
$116K - $166K *
Unlock potential by serving as a key technical resource, bridging information security and customer success. Collaborate with teams to enhance security posture, address inquiries, and ensure complianc...
1 week ago
Early Careers New Grad - Leadership Development Program (REMOTE)
$63K - $114K *
Unlock your potential by supporting strategic projects and planning in health care. Collaborate with diverse teams to drive business goals, enhance analytical capabilities, and develop innovative solu...
Reposted today
$90K - $110K *
Lead the management of clinical trial agreements and budgets, ensuring quality and timely deliverables. Collaborate with cross-functional teams to resolve contract issues and enhance processes while g...
2 weeks ago
$160K - $180K *
Champion growth and satisfaction by managing key Ecosystem client relationships. Drive sales of innovative data solutions in Life Sciences, leveraging deep industry knowledge to meet client needs and...
6 days ago
$140K - $190K *
Take ownership of defining and operationalizing a customer ROI framework across teams, fostering strategic growth initiatives through measurable value outcomes while enabling effective customer engage...
Reposted 1 month ago
Physician Assistant or Acute Care Nurse Practitioner - Inpatient Endocrinology Full Time Days
$100K - $120K *
Transform patient care by leveraging your expertise in endocrinology and diabetes management. Collaborate with a dedicated team to enhance health outcomes, mentor future practitioners, and drive quali...
2 days ago
Senior Complex Claims Specialist - Allied Healthcare
$140K - $170K *
Optimize claims handling by leading high-severity Allied Healthcare Professional Liability claims from inception to resolution. Collaborate with internal and external partners to ensure best practices...
2 days ago
What types of $100,000+ jobs can I find in Illinois?
Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.
Are there high-paying jobs outside Chicago?
Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.
How can I find Illinois jobs that pay $100,000 or more?
Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.
Do Illinois job listings include remote or hybrid roles?
Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.