Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.
Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.
Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.
Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.
$80K - $95K *
Join a dynamic team to enhance decision-making and support EHRM initiatives. Drive program management, facilitate stakeholder engagement, and contribute to strategic communications while ensuring effe...
3 weeks ago
$125K - $153K *
Engineer the strategic development and operational support of advanced collaboration technologies, ensuring seamless integration across diverse campuses while enhancing user experience and driving pro...
Reposted 4 days ago
VP, Integrated Insights & Client Impact
$187K - $348K *
Transform client engagement by leading proactive insights delivery across Clinical, Operational, and Strategy Intelligence. Drive measurable impact through data-driven narratives and build a high-perf...
Reposted 1 week ago
Clinical AI Technical Integration Specialist
$110K - $130K *
Unlock potential by driving technical integration and validation for Ambient AI Scribe initiatives. Collaborate with clinical teams to enhance workflows, troubleshoot issues, and ensure operational re...
5 days ago
Senior Associate, Market Intelligence
$80K - $95K *
Optimize market intelligence within global diagnostics by leading analytical work, synthesizing data, and translating complex insights into actionable recommendations. Collaborate with diverse stakeho...
1 week ago
Registered Nurse (RN) Emergency Room
$66K - $100K *
Deliver compassionate nursing care by supporting patients and families, collaborating with healthcare teams, and promoting independence through education and emotional support. Ensure quality care by...
3 days ago
Registered Nurse (RN) Emergency Room
$70K - $106K *
Join a team that delivers critical care and compassion to our patients in need. As essential members of the medical staff, you will provide expert nursing care and support to patients and families dur...
4 weeks ago
Finance Supervisor, Product Development, Science & Technology (PDS&T)
$110K - $130K *
Optimize financial planning and analysis processes, delivering timely insights and variance reports. Collaborate with business leaders to enhance reporting accuracy and drive strategic decisions withi...
3 days ago
$95K - $115K *
Unlock the potential of seamless data exchange by analyzing EDI requirements, developing maps, and supporting integrations. Collaborate with partners to ensure efficient transactions and enhance elect...
2 days ago
$100K - $104K *
Transform financial management for Foreign Military Sales by providing essential support and analysis. Collaborate with stakeholders to ensure compliance and accuracy in financial reporting and case m...
4 days ago
Senior Agentic AI Engineer/Developer
$87K - $161K *
Launch your career by designing and implementing AI-driven security solutions that enhance automation and reduce repetitive tasks. Collaborate across teams to build robust, secure applications and str...
Yesterday
Manager - Statistical Programming (Hybrid)
$120K - $145K *
Unlock your potential by leading a team of Statistical Programmers in the development of innovative pharmaceutical products. Drive statistical programming activities, ensuring quality and consistency...
2 weeks ago
$70K - $109K *
Lead radiologic operations, ensuring patient comfort and departmental efficiency. Oversee workflow, manage staff training, and maintain high standards of care while fostering a collaborative environme...
3 days ago
$140K - $160K *
Accelerate progress at a dynamic tech firm by owning the full sales cycle for mid-market practices. Collaborate with leadership to shape strategy and drive impactful relationships, ensuring success in...
3 days ago
Senior Analyst, Reconciliation
$90K - $105K *
Unlock your potential by ensuring data accuracy and compliance in a fast-paced environment. Collaborate with teams to enhance processes and drive operational excellence while managing reconciliations...
3 weeks ago
Associate Engineer, Technology II
$80K - $95K *
Transform computational research by implementing and supporting HPC solutions. Collaborate with R&D teams to enhance software deployment, integrate applications, and streamline user access, contributi...
3 weeks ago
Associate Director, IT Service Desk
$117K - $161K *
Optimize support operations by enhancing service delivery, leading a hybrid team, and driving transformation initiatives to improve customer experiences and operational efficiencies across technology...
Reposted yesterday
Solutions Architect 3 AI / Digital Architecture
$135K - $160K *
Lead the design and implementation of innovative AI solutions, ensuring robust architecture for complex systems. Collaborate with cross-functional teams to translate business needs into scalable, secu...
3 weeks ago
$80K - $95K *
Empower the clinical support team by coordinating complex cases, mentoring junior counselors, and enhancing protocols. Your expertise will drive effective communication and quality standards in geneti...
1 week ago
$95K - $115K *
Manage data acquisition and integration for Flag Football, collaborating with multiple stakeholders to ensure seamless data flow, establish standards, and translate business needs into actionable data...
3 weeks ago
Corporate Charge Capture Auditor, Outpatient
$63K - $101K *
Optimize compliance in Interventional Radiology charge capture by conducting audits, educating teams, and enhancing coding practices. Collaborate with clinical departments to identify and rectify codi...
2 weeks ago
Senior Director, Head of Enterprise Clinical AI & Technology - Remote - The Cigna Group
$193K - $322K *
Join a team that leads the charge in advancing clinical AI and technology, shaping solutions that enhance clinician experience and patient outcomes while navigating complex healthcare environments...
1 month ago
$90K - $110K *
Unlock your potential as a Physician Assistant, blending in-person and telehealth care to enhance patient outcomes and experience through expert clinical skills and innovative technology...
1 month ago
Associate Manager, Clinical Health Services
$88K - $190K *
Provide oversight and leadership for healthcare management teams, ensuring effective interventions and adherence to regulatory standards while achieving operational and quality objectives across the c...
2 days ago
$75K - $117K *
Provide exceptional ultrasound and vascular imaging services while ensuring patient safety and comfort. Collaborate with medical professionals, and maintain optimal equipment functionality in a dynami...
Reposted 4 days ago
What types of $100,000+ jobs can I find in Illinois?
Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.
Are there high-paying jobs outside Chicago?
Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.
How can I find Illinois jobs that pay $100,000 or more?
Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.
Do Illinois job listings include remote or hybrid roles?
Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.