Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.
Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.
Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.
Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.
$67K - $113K *
Advance our security posture by managing access controls and identity solutions, ensuring data integrity and compliance across cloud and on-premises environments, while effectively addressing security...
1 month ago
Senior Medical Director, Oncology Clinical Development (GI)
$210K - $250K *
Shape the future of clinical development by overseeing clinical trials, ensuring adherence to regulations, and integrating scientific insights into strategies that enhance product efficacy and safety...
3 weeks ago
Healthcare-Life Sciences Practice Director
$160K - $200K *
Shape your career by launching and leading a transformative healthcare consulting practice. Drive growth through strategic engagements, build a robust team, and establish innovative solutions in data...
Reposted 1 month ago
Senior Scientific Director, Oncology Clinical Development (NHL & Leukemia)
$166K - $200K *
Unlock potential by leading clinical development programs, ensuring high-quality data and compliance. Collaborate with cross-functional teams to drive scientific strategy and oversee project integrity...
2 weeks ago
Account Executive - Biopharma Clinical Research, Study Conduct
$110K - $130K *
Engage with pharmaceutical partners to drive revenue through AI-driven solutions. Build strategic relationships and develop account plans while collaborating across teams. Utilize your sales expertise...
Reposted 1 month ago
$165K - $166K *
Drive technical excellence by leading cross-functional teams, gathering requirements, and proposing innovative solutions. Mentor peers while managing enhancements and ensuring quality in application d...
2 weeks ago
Director, Business Development - Locum Tenens
$115K - $130K *
Grow and strengthen strategic relationships with healthcare systems to drive business success. Optimize networking and sales strategies to secure new contracts and expand our reach within the healthca...
1 month ago
Senior Manager, Data Management, Office of Safety Operations
$120K - $145K *
Lead data management initiatives to enhance safety data solutions, ensuring high-quality outputs and compliance. Collaborate with stakeholders to optimize processes and drive operational excellence in...
3 days ago
Director, Insights and Analytics
$150K - $180K *
Optimize your career by leading insights-driven strategies that shape brand decisions. Collaborate across functions to deliver actionable market research and analysis, driving impactful outcomes in a...
2 weeks ago
$85K - $100K *
Drive comprehensive audits, mentor junior staff, and ensure compliance with clinical and financial standards. Enhance revenue cycle performance by identifying issues and recommending improvements, whi...
3 weeks ago
$112K - $130K *
Collaborate with VA stakeholders to analyze business needs and drive effective solutions for the modernization of financial tracking tools, ensuring clear, actionable requirements are delivered throug...
3 weeks ago
Manager Regulatory Affairs, Global Regulatory Strategy US & Canada - Hybrid
$110K - $130K *
Shape the future of regulatory strategy by managing US and Canada submissions, ensuring compliance, and collaborating with cross-functional teams to drive product commercialization and regulatory exce...
3 days ago
Business Senior Analyst (BluesNet)
$107K - $156K *
Partner with us to develop strategies for national healthcare delivery, leading product integration and analysis for complex projects. Collaborate with stakeholders to enhance operational processes an...
2 weeks ago
Deal Advisory Director (Healthcare)
$192K - $334K *
Tackle complex healthcare M&A engagements, leading due diligence efforts, and collaborating with clients and teams to drive value. Manage multiple projects while utilizing your expertise to influence...
Reposted 2 weeks ago
USCAN Services Finance Analyst - FP&A Operations
$105K - $158K *
Optimize financial performance by partnering with operations to enhance cost efficiency and profitability. Drive strategic investment decisions and support budgeting processes while ensuring alignment...
6 days ago
$119K - $179K *
Support the integration and harmonization of clinical data by designing FHIR-compliant models and pipelines, ensuring data accuracy and usability for patient care and research initiatives across the o...
2 weeks ago
$93K - $140K *
Accelerate progress at defining technical requirements and solutions, collaborating with business experts to enhance operational processes. Lead projects, mentor analysts, and ensure alignment of tech...
2 weeks ago
Director, Quality Intelligence & Causal Analysis
$200K - $240K *
Pioneer quality intelligence and causal analysis initiatives, transforming data into actionable insights. Lead root cause analyses and predictive risk assessments to enhance audit quality and support...
2 days ago
Account Executive, Small Group
$75K - $90K *
Lead the charge in driving sales growth by engaging independent physician practices. Utilize your expertise in full-cycle sales to build relationships, conduct virtual demos, and collaborate with team...
2 weeks ago
Marketing Data Analytics Engineer (US)
$87K - $97K *
Shape the future of marketing analytics by building robust data pipelines and automating reporting workflows. Collaborate with cross-functional teams to enhance data quality and leverage AI tools for...
2 weeks ago
Head of National Strategic Accounts
$250K - $300K *
Champion strategic growth by leading the charge to secure complex health system accounts. Drive transformative deals with hands-on coaching, leveraging deep relationships and expertise to elevate team...
Reposted 1 week ago
eDiscovery Analyst, Enterprise Accounts
$100K - $120K *
Champion the management and execution of complex e-discovery projects, collaborating with legal teams to ensure successful outcomes. Oversee multiple projects while mentoring a team, maintaining quali...
1 week ago
Director of Health and Wellness
$100K - $120K *
Unlock your potential by directing a comprehensive Health and Wellness Program, ensuring top-tier resident care and regulatory compliance while managing clinical budgets and leading a dedicated team i...
1 week ago
Director, Actuarial Science (Medicaid Rate Advocacy, Month End Close, Forecasting)
$135K - $237K *
Shape the future of actuarial science by leading innovation, guiding strategies, and enhancing financial performance through advanced modeling and regulatory compliance. Collaborate with senior leader...
Reposted 1 week ago
Financial Intelligence Analyst-Workday
$85K - $115K *
Transform finance operations by providing expert Workday support across financial accounting. Collaborate with cross-functional teams to enhance processes from record to report, ensuring smooth transi...
3 weeks ago
What types of $100,000+ jobs can I find in Illinois?
Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.
Are there high-paying jobs outside Chicago?
Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.
How can I find Illinois jobs that pay $100,000 or more?
Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.
Do Illinois job listings include remote or hybrid roles?
Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.