Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.
Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.
Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.
Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.
U.S. Engagement Manager, Healthcare Services - 2026
$241K *
Champion client engagements and lead teams in the healthcare services sector, driving growth strategies and delivering impactful insights while managing complex projects and fostering team development...
1 week ago
$78K - $156K *
Join a team that's dedicated to enhancing business systems through design, configuration, and support. As a Senior Application Analyst, you'll lead improvements, mentor junior analysts, and ensure sea...
1 week ago
$78K - $156K *
Manage system design, enhancements, and support as a Senior Application Analyst. Collaborate with stakeholders, mentor junior team members, and improve workflows while ensuring application performance...
1 month ago
Director - Management Consulting - State & Local Government (HHS)
$179K - $298K *
Champion a dynamic team dedicated to enhancing state health and human services through strategic client engagement, quality delivery, and innovative business development while leading a diverse consul...
Reposted 4 weeks ago
$128K - $152K *
Drive advanced data analysis and regulatory reporting to enhance data quality and compliance. Collaborate with stakeholders to transform complex data into actionable insights, ensuring accuracy and op...
Reposted 1 week ago
VP Sales, Provider Analytics - Remote
$130K - $240K *
Lead national sales strategy for AI-enabled healthcare analytics, driving provider performance and value-based care success. Build executive relationships and develop a high-performing sales team to a...
3 days ago
Home Health RN Case Manager, South Central Chicago
$79K - $118K *
Lead the delivery of high-quality home health nursing care, fostering therapeutic relationships with patients and families. Collaborate with interdisciplinary teams to ensure effective care planning a...
Reposted today
Senior Associate - Revenue Cycle - Healthcare
$85K - $115K *
Empower client success by analyzing revenue cycles, enhancing processes, and managing relationships. Collaborate on qualitative and quantitative projects, driving operational improvements with your an...
3 weeks ago
Business Insights Analyst, Remote US
$80K - $95K *
Grow your career with a dynamic role that drives actionable insights across e-commerce and service delivery. Collaborate with stakeholders to analyze data, build impactful reports, and enhance busines...
4 days ago
Principal, Data Governance Platforms
$149K - $224K *
Shape the future of data governance by leading the design and implementation of enterprise platforms that ensure data integrity, quality, and compliance across the organization, while collaborating wi...
1 week ago
Clinical Informatics Specialist
$102K - $133K *
Unlock potential by optimizing clinical systems and driving informatics initiatives. This role combines strategy with hands-on support across EHR applications, fostering collaboration to enhance workf...
Reposted 2 weeks ago
DRG Coding Auditor - MS-DRG and APR-DRG
$92K - $160K *
Analyze and audit claims using coding principles and clinical guidelines to ensure accurate coding and documentation. Leverage expertise in DRG coding and medical billing to support recovery auditing...
Reposted 1 week ago
$148K - $256K *
Shape the future of data engineering by architecting scalable, cloud-native data platforms on Azure and Databricks. Influence the organization’s data practices to leverage AI-driven insights, driving...
Reposted 1 week ago
$195K - $245K *
Lead transformative AI strategy and implementation engagements in healthcare, guiding a team to deliver measurable value while driving business development and practice growth across multiple sectors...
1 week ago
$112K - $169K *
Help us enhance healthcare integration by designing and implementing HL7 interfaces for Perinatal Systems. Collaborate with clients and vendors to streamline hospital IT systems, ensuring efficient da...
3 weeks ago
Senior Manager, Clinical Data Systems
$120K - $145K *
Elevate your career by leading a high-performing team in data science, driving innovation and operational excellence in clinical trials. Oversee technology implementations and talent development to ma...
2 weeks ago
Manager, Business Development, National Center for Clinical Trials (NCCT)
$114K - $171K *
Join a team that's driving growth in clinical trials by identifying and securing partnerships. Collaborate with cross-functional leaders to enhance visibility and expand opportunities, ensuring seamle...
3 weeks ago
Mgr, Business Analysis, Workforce Initiatives, Data & Analytics
$66K - $145K *
Drive impactful workforce analytics and business intelligence initiatives by transforming data into strategic insights that enhance talent and operational outcomes. Collaborate across departments to f...
Reposted 1 week ago
Medical Review Analyst - Medicare
$66K - $106K *
Lead the charge in conducting medical record reviews and applying clinical judgment to ensure accurate claim payment decisions while supporting fraud investigations and compliance efforts...
2 weeks ago
$75K - $100K *
Join the charge in supporting our enterprise IT environment by managing user identities, deploying applications, and troubleshooting complex issues across hybrid infrastructures. Leverage your experti...
3 days ago
$75K - $100K *
Drive excellence by supporting our enterprise IT environment, managing user identities, and troubleshooting complex issues across hybrid systems. Collaborate with teams to ensure seamless application...
3 days ago
Senior Analyst, Client Insights
$124K - $145K *
Join our Client Insights team to transform data into actionable insights that drive sales and merchant retention. Collaborate across analytics, product, and strategy to enhance AI-driven solutions for...
1 week ago
$88K - $117K *
Unlock potential by transforming raw data into impactful insights. Build robust data models and pipelines to enhance decision-making processes across departments. Collaborate effectively to ensure dat...
1 month ago
$88K - $117K *
Accelerate data-driven decision-making by building robust data models and pipelines. This role is essential for transforming raw data into actionable insights, ensuring data quality, and optimizing pe...
Yesterday
$90K - $120K *
Transform financial operations by leveraging your analytical skills to enhance budgeting, forecasting, and reporting processes. Collaborate with diverse teams to ensure accurate financial management a...
5 days ago
What types of $100,000+ jobs can I find in Illinois?
Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.
Are there high-paying jobs outside Chicago?
Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.
How can I find Illinois jobs that pay $100,000 or more?
Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.
Do Illinois job listings include remote or hybrid roles?
Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.