Explore $100K+ Jobs in Wisconsin

Find vetted professional jobs in Wisconsin with salaries of $100,000 or more on Ladders. From established employers in Milwaukee and Madison to opportunities across Green Bay, Eau Claire, and beyond, explore roles that match your experience and career goals.

High-Paying Careers Across Wisconsin

Wisconsin’s economy includes healthcare, manufacturing, financial services, technology, insurance, and professional services. Depending on your background, you may find leadership, engineering, healthcare, sales, finance, and technology roles among the state’s higher-paying opportunities. Job availability and compensation vary by employer, location, and qualifications.

Where to Find Wisconsin Jobs

Search for opportunities in major employment centers such as Milwaukee, Madison, Green Bay, Appleton, and Waukesha, or explore jobs elsewhere in the state. Use location and role preferences to focus your search on positions that fit your needs.

Find a Role That Fits Your Experience

Review job requirements, compensation details, and workplace expectations before applying. Keep your résumé current and highlight measurable accomplishments, relevant skills, and leadership experience to help employers understand the value you bring.

Start Your Wisconsin Job Search

Browse Ladders for vetted professional openings paying $100,000 or more. New listings and hiring needs change over time, so check back regularly and apply to roles that align with your career goals.

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$250K - $300K *

Join a team that's dedicated to providing compassionate, evidence-based care for women. Collaborate with a multidisciplinary team to deliver high-quality obstetrical and gynecological services in a su...

Today

  •   Less than 5 years exp.  •   Healthcare

$73K - $110K *

Empower patient care as a Registered Nurse, delivering high-quality, evidence-based nursing in an ambulatory setting. Collaborate with interdisciplinary teams to advocate for patients and promote opti...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$189K - $246K *

Lead clinical pharmacology strategies, integrating PK/PD assessments across development phases. Collaborate with cross-functional teams to guide decision-making and regulatory submissions, ensuring al...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$190K - $300K *

Champion scientific exchange and research initiatives in gastrointestinal immunology, engaging with key scientific leaders to enhance understanding and support clinical trials while fostering an inclu...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $90K *

Shape the future of Cell and Gene Therapy by providing expert application support, driving customer integration, and enhancing product utilization through collaboration and technical guidance across t...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Champion patient care by providing comprehensive family medicine services, engaging in clinical teaching, and participating in scholarly activities. Collaborate with faculty to enhance education and s...

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$98K - $132K *

Transform healthcare by leading Risk Adjustment strategies and educational initiatives. Collaborate with teams to enhance coding accuracy and documentation, ensuring compliance and delivering impactfu...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$130K - $150K *

Lead the charge in integrating complex hospital data systems into Astra OS. Own end-to-end data pipelines, collaborate with customers, and design scalable solutions that enhance healthcare operations...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$191K - $330K *

Champion compliance with the Mental Health Parity Act by advising leadership, coordinating audits, and developing strategies to ensure member access to mental health services while managing legal risk...

1 week ago

  •   11 - 15 years exp.  •   Hospitals & Medical Centers

$111K - $167K *

Empower your career by leading IT systems development, implementation, and maintenance. Oversee complex networks, ensure security, and drive automation, all while collaborating to enhance operational...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Champion operational excellence in Radiology Services, leading teams in X-ray, Breast Imaging, and IR. Drive process improvements and enhance patient access in a dynamic healthcare environment while m...

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Elevate market presence by driving adoption of innovative cardiac imaging solutions. Collaborate with healthcare professionals to enhance patient care, achieve sales targets, and optimize business str...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$250K - $300K *

Shape the future of diagnostic radiology by joining a dynamic team focused on oncologic imaging and theranostics. Collaborate in a supportive environment that values education, research, and work-life...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive excellence in patient care by managing imaging operations, enhancing staff performance, and ensuring compliance with healthcare standards across multiple service lines. Support collaborative wor...

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$76K - $114K *

Unlock potential by driving growth in Electrophysiology-focused Ambulatory Surgery Centers. Leverage clinical expertise to build relationships, enhance product adoption, and ensure customer satisfacti...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$174K - $224K *

Empower organizations by shaping data governance strategies that enhance security, compliance, and operational resilience. Collaborate with cross-functional teams to deliver impactful governance solut...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$175K - $250K *

Join a team that's optimizing medical cost management and driving financial performance across Commercial lines. Leverage your expertise in healthcare economics to influence strategic contracting and...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$272K - $340K *

Elevate your career by leading CMC Regulatory strategy and execution. Drive submissions, build a high-performing team, and engage with global health authorities to ensure compliance and success in dru...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Drive the enterprise data strategy and governance, ensuring data quality, compliance, and accessibility. Lead cross-functional teams to foster a data-rich culture, enabling advanced analytics and AI r...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to enhancing contract management and customer experience. Leverage your expertise in contract administration and customer service to streamline processes and ensure compli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the quality assurance efforts for commissioning, qualification, and validation across multiple manufacturing sites, ensuring compliance with cGMP standards while collaborating with cross-function...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $158K *

Transform customer experiences by managing complex technical projects, ensuring product quality, and facilitating cross-functional collaboration. Leverage your leadership skills to drive stakeholder c...

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$105K - $158K *

Unlock potential by managing complex projects in digital healthcare, ensuring product quality and customer satisfaction. Collaborate with cross-functional teams to drive program success and address st...

Waukesha, WIRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$150K - $180K *

Join a dynamic team to lead and scale clinical operations, overseeing performance and process optimization. Build accountable teams, manage metrics, and partner with stakeholders to enhance operationa...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$344K *

Join a team that's committed to excellent patient care in a vibrant multi-specialty clinic. Enjoy zero call, flexible hours, and a collaborative environment with a dedicated team of professionals focu...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Wisconsin?question toggle

    Listings may include professional and leadership roles in fields such as healthcare, manufacturing, technology, finance, insurance, engineering, and sales. Openings depend on current employer hiring needs and your qualifications.

  • Which Wisconsin cities have high-paying job opportunities?question toggle

    Milwaukee, Madison, Green Bay, Appleton, and Waukesha are among Wisconsin’s major employment centers. Opportunities may also be available in other cities and communities across the state.

  • Are the Wisconsin jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for specific compensation, requirements, and employer details.

  • How can I find the right job in Wisconsin?question toggle

    Filter listings by location, role, and other preferences, then compare responsibilities and qualifications with your experience. Tailor your résumé to emphasize relevant accomplishments and skills.

  • Do all jobs in Wisconsin pay at least $100,000?question toggle

    No. This page is intended to help you explore professional listings on Ladders that meet its $100,000-or-more salary focus. Compensation and availability vary by role and employer.