Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$73K - $130K *

Drive the acquisition and usability of clinical data to enhance healthcare outcomes. Collaborate with diverse teams to analyze data gaps, implement integrations, and optimize processes, ensuring timel...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $210K *

Lead the charge in driving enterprise growth within healthcare by building relationships with national and regional health plans. Own new logo acquisition and expansion, leveraging a robust support sy...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$210K - $250K *

Grow your career by providing comprehensive diagnostic radiology services, including consultations and interpretations for a diverse patient population. Collaborate remotely to ensure timely and accur...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$240K - $269K *

Advance your career by leading national account strategies in oncology, fostering relationships with health plans and PBMs. Drive coverage, reimbursement, and adoption initiatives while collaborating...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive data integrity and operational excellence by resolving complex payer data issues, collaborating across teams, and enhancing data quality for value-based care initiatives. Play a key role in opti...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Transform early phase clinical trials by leading design, execution, and oversight. Collaborate with cross-functional teams to ensure compliance and data integrity while managing project performance an...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$167K - $300K *

Unlock your potential by leading regional oncology thought leader engagement and advocacy strategies. Collaborate with cross-functional teams to shape brand strategy and launch planning for innovative...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$69K - $104K *

Unlock your potential as a coding auditor, ensuring accurate documentation and coding while promoting compliance and reimbursement optimization. Collaborate with coders and specialists to enhance proc...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Transform healthcare operations by leading a dedicated team in a critical illness recovery hospital. Drive quality care, employee engagement, and strategic initiatives while ensuring compliance and op...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $165K *

Join a team that's dedicated to enhancing clinical education and customer experience. In this role, you'll drive training strategies and support ultrasound product implementation, impacting patient ca...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$193K - $262K *

Lead and optimize field effectiveness initiatives, driving sales performance through insights and operational excellence. Manage a high-performing team while collaborating cross-functionally to enhanc...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Champion clinical education and training by delivering expert knowledge and support to enhance user competencies and optimize patient care within a defined territory. Build strong relationships with s...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Business Services

$149K - $206K *

Empower your career by delivering exceptional virtual care as you evaluate and treat diverse patient needs, ensuring optimal outcomes through collaboration and quality measures in a dynamic team envir...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$136K - $187K *

Lead patient education and support initiatives for individuals affected by generalized Myasthenia Gravis. Collaborate with caregivers and healthcare teams to enhance treatment coordination and empower...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$198K - $268K *

Lead the global GMP/GDP audit organization, enhancing predictive compliance intelligence while mitigating risks through advanced analytics and effective audit strategies...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$76K - $114K *

Elevate the clinical sales landscape by driving growth in Electrophysiology-focused Ambulatory Surgery Centers. Leverage your clinical expertise to build relationships, enhance product adoption, and e...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Join a dynamic team to lead the creation of impactful scientific content, enhancing medical education and patient outcomes. Collaborate cross-functionally, mentor writers, and drive excellence in heal...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Unlock your potential by leading the development of innovative DRGV services, enhancing billing and coding optimization. Collaborate across teams to create scalable solutions that drive operational ex...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $160K *

Oversee the operational planning and execution of clinical trials, ensuring compliance with regulatory standards while managing cross-functional teams to meet project timelines, budgets, and quality o...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$68K - $126K *

Transform medical billing operations by leading a team to optimize systems, enhance service delivery, and drive continuous improvement through technology and structured practices, ensuring accountabil...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $250K *

Make your mark at the forefront of clinical operations, driving global studies from strategy to execution while ensuring operational integration across teams and vendors for successful Phase 3 program...

United StatesRemote

1 month ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$223K - $313K *

Shape the future of behavioral health care strategy and operations. Leverage your medical expertise to enhance quality, operational efficiency, and patient outcomes while navigating complex regulatory...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$76K - $114K *

Shape the future of healthcare by driving growth in Electrophysiology-focused Ambulatory Surgery Centers. Leverage your clinical expertise to build relationships, enhance product adoption, and ensure...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$227K - $313K *

Elevate your career by leading strategic reimbursement initiatives, optimizing revenue cycles, and collaborating with key stakeholders to enhance patient access and billing processes in a dynamic heal...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$136K - $187K *

Unlock potential by serving as a vital resource for patients and caregivers, providing education and support for managing generalized Myasthenia Gravis while coordinating treatment and navigating insu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.