Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
Sr. / Principal Medical Writer (Regulatory focus) - Sponsor-dedicated; NA/CAN/UK
$110K - $130K *
Advance your career by leading medical writing projects in a regulatory environment. Collaborate with cross-functional teams to produce high-quality documents, ensuring compliance with industry standa...
6 days ago
Sr. / Principal Medical Writer (Regulatory focus) - Sponsor-dedicated; NA/CAN/UK
$80K - $175K *
Champion the creation of high-quality regulatory documents, managing writing tasks and leading reviews. Collaborate across teams to ensure clarity and compliance, mentoring junior writers while delive...
Reposted 2 weeks ago
$80K - $95K *
Empower clients by managing energy procurement operations, leading RFP processes, and delivering market insights. Collaborate with suppliers and customers to optimize strategies in deregulated electri...
2 weeks ago
$120K - $150K *
Champion demand generation by executing integrated campaigns to drive pipeline growth and revenue, collaborating cross-functionally with Sales and Product teams for fuel growth through strategic marke...
Reposted 4 weeks ago
21GRAMS- Director, Product Design
$140K - $155K *
Empower teams to elevate product design through strategic vision, fostering collaboration across disciplines to create impactful digital experiences that meet user needs and business goals while ensur...
6 days ago
Director, Enterprise Portfolio Enablement
$110K - $130K *
Drive your career with a strategic role focused on enhancing project management standards and integrating enterprise initiatives. Collaborate with leaders to improve clarity, prioritization, and execu...
4 weeks ago
Senior Oracle Business Analyst, Finance
$112K - $140K *
Unlock potential by bridging finance and IT as you optimize Oracle Fusion Cloud. Drive process improvements, manage updates, and enhance data flows while ensuring seamless operations and stakeholder e...
1 week ago
Sr. Staff Attorney (Regulatory)
$142K - $177K *
Lead legal initiatives by drafting documents, managing records, and providing counsel. Collaborate with executives to shape organizational direction while ensuring compliance and supporting continuous...
Today
Specialist Manager, Government Client Contracts Management (Air Force)
$93K - $191K *
Optimize federal contract administration by leading complex engagements, advising on strategy, and ensuring compliance throughout the contract lifecycle. Collaborate with stakeholders to enhance opera...
3 days ago
Configuration Lead, Compensation
$117K - $161K *
Drive your career with this strategic role, leading Workday Compensation solutions. Collaborate with cross-functional teams to optimize compensation processes, ensuring alignment with business goals a...
Today
Rare Disease Key Account Manager - Neurology - Delta South
$110K - $130K *
Lead the charge in transforming rare disease treatment by partnering with key stakeholders to enhance patient access, streamline operations, and drive business growth across health systems and special...
Today
Lead Solutions Engineer, Strategic
$140K - $170K *
Shape the future of healthcare technology by leveraging your expertise to drive sales success. Collaborate with cross-functional teams to deliver tailored solutions, engage customers, and enhance prod...
2 weeks ago
Senior Copywriter, Promotional Medical Writing
$80K - $100K *
Shape the future of medical communications by crafting high-quality, scientifically accurate content. Collaborate with diverse teams to deliver impactful resources that meet client needs while mentori...
2 days ago
Executive Director, Statistical Programming
$298K - $340K *
Join a dynamic team to lead strategic statistical programming initiatives, ensuring top-quality deliverables and compliance across diverse clinical trials. Collaborate with cross-functional partners t...
Reposted 3 weeks ago
$72K - $116K *
Engage in financial analysis and reporting, developing forecasts and insights. Collaborate across departments to enhance business outcomes and present findings to management, driving strategic decisio...
Reposted 1 week ago
Senior Director, Quality Control (QC) Program Implementation Lead
$216K - $243K *
Pioneer advancements in vaccine research and development, driving global immunization efforts. Collaborate across teams to ensure compliance and effective delivery of safe vaccines, enhancing public h...
1 week ago
$110K - $130K *
Accelerate progress at driving strategic M&A initiatives by managing deal execution, from financial modeling to synergy analysis, while collaborating with senior leadership and ensuring organized proc...
Reposted 4 weeks ago
Applications Analyst- Epic Professional Billing
$67K - $111K *
Elevate your career by providing critical analysis and programming support for application software, ensuring a comprehensive and integrated information network that meets diverse customer needs and e...
2 days ago
Senior Manager, Partner & Network Delivery
$100K - $120K *
Shape the future of partner-driven installations by ensuring project success, coordinating activities, and maintaining high standards throughout the delivery process. Lead teams to manage multiple pro...
1 month ago
$190K - $300K *
Build strategic relationships with scientific leaders to drive innovation in Pulmonary Hypertension. Engage in scientific exchange, support research initiatives, and enhance understanding of therapeut...
Reposted 1 week ago
Associate Director, Real-World Analytics Programming
$186K - $233K *
Empower the future of real-world analytics by leading programming activities for observational studies, ensuring high-quality deliverables through collaboration with cross-functional teams and innovat...
3 weeks ago
$112K - $131K *
Elevate your career by leading complex financial analyses and strategic initiatives. As a senior contributor, you'll drive enhancements in reporting, support business decisions, and mentor team member...
3 weeks ago
Account Executive - Government
$80K - $95K *
Grow your career by developing and maintaining key customer relationships, driving sales success, and collaborating with teams to exceed goals. Leverage your expertise in account management and sales...
2 weeks ago
Technical Support Engineer (New England)
$72K - $112K *
Serve as a vital technical support resource in healthcare technology, ensuring system stability and customer satisfaction while managing service requests and collaborating with teams for quick resolut...
Reposted 3 weeks ago
Director, Business Strategy and Operations, Global Clinical Development Operations (GCDO)
$192K - $288K *
Join us as a strategic partner in global clinical development operations, driving workforce planning, budget management, and continuous improvement initiatives. Collaborate with leadership to enhance...
Yesterday
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.