Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
$160K - $180K *
Elevate customer success by managing strategic federal programs, ensuring seamless implementation and adoption of innovative solutions. Collaborate with stakeholders to drive project execution and enh...
Today
Validation Engineers & Leads (cGMP) - Project Farma
$60K - $105K *
Join a team that's dedicated to enhancing patient lives through innovative validation solutions. Collaborate across functions to deliver high-quality outcomes while mentoring others and driving projec...
4 weeks ago
$275K - $350K *
Lead the charge in transforming operations by integrating AI and technology to enhance member and clinician experiences, ensuring efficient care delivery and operational excellence across a distribute...
1 week ago
Staff Bioinformatics Scientist, Clinical Applications
$146K - $196K *
Transform genomic insights into clinical applications by designing automated solutions and integrating AI/ML approaches. Collaborate with cross-functional teams to enhance variant curation and ensure...
1 week ago
Enterprise Core Sales Engineer - West
$139K - $184K *
Launch your career by facilitating critical technical sales and supporting senior sellers. Drive impact through intricate integrations, share insights with your team, and develop key customer relation...
Reposted 4 weeks ago
Principal GTM Systems Architect
$200K - $220K *
Lead the design and implementation of advanced systems and workflows for GTM teams. Drive technical initiatives to optimize scalability, leverage AI, and mentor engineers, ensuring robust architectura...
Reposted 2 weeks ago
Field Clinical Specialist (Remote)
$115K - $180K *
Champion the use of innovative medical technology by training and supporting clinical staff in the effective application of the Globe PF System, ensuring successful clinical trials and enhancing patie...
1 week ago
$65K - $108K *
Unlock potential by providing advanced technical support and engineering expertise to resolve complex production issues. Manage end-to-end case ownership while collaborating with teams to enhance serv...
3 weeks ago
Applications Analyst-Clinical-Sr
$89K - $136K *
Innovate clinical application support to enhance patient care efficiency. Manage software upgrades, coordinate with IT teams, and lead projects while ensuring compliance and effective communication ac...
Today
Staff Bioinformatics Engineer, Clinical Applications
$134K - $179K *
Lead the charge in bridging genomic variants with clinical insights, collaborating with scientists to automate and scale curation workflows. Drive innovation in AI/ML applications while ensuring softw...
1 week ago
Senior Product Marketing Manager
$120K - $145K *
Elevate your career by leading strategic product marketing initiatives, managing high-impact projects, and collaborating cross-functionally to drive value propositions in enterprise technology, includ...
3 weeks ago
Regional Account Manager-Eastern Midwest Region
$186K - $234K *
Grow your career by driving sales and building relationships in the neurology and rare disease sectors. Collaborate with healthcare professionals to enhance patient care and achieve sales targets whil...
3 weeks ago
$92K - $120K *
Join a dynamic team as a Medical Claims Auditor, ensuring compliance and integrity in healthcare payments. Collaborate with cross-functional teams to identify fraud, waste, and abuse while leveraging...
2 days ago
Surgical Sales Executive- Chicago/Minneapolis
$110K - $130K *
Drive growth by promoting innovative regenerative medicine solutions. Leverage your expertise in vascular surgery sales and establish strong customer relationships to achieve targets and make a meanin...
Reposted 5 days ago
Regional Sales Director, Enterprise - Southeast
$148K - $248K *
Shape the future of software sales by leading a dynamic team in the Southeastern US. Drive revenue growth, enhance customer relationships, and foster a high-performing culture while leveraging GitLab...
2 weeks ago
$210K - $260K *
Transform the workplace culture and integration of two organizations, ensuring support for clinicians and staff while enhancing benefits, compensation, and recruitment strategies to foster a unified m...
3 days ago
Manager, Provider Operations - Provider Data
$73K - $115K *
Help us drive operational excellence in provider data management, ensuring accuracy and efficiency throughout the lifecycle. Collaborate with teams to enhance processes, leverage insights, and impleme...
3 days ago
$140K - $228K *
Lead the charge in enhancing cybersecurity by driving detection engineering, incident response, and automation. Collaborate cross-functionally to secure cloud architectures and improve operational eff...
1 week ago
AVP/VP, Client Services (RadScience)
$175K - $205K *
Transform client relationships and drive growth by leading strategic initiatives in scientific visualization, medical education, and digital engagement. Manage multidisciplinary teams and oversee acco...
Reposted 2 weeks ago
$80K - $155K *
Join a team that's redefining energy solutions by designing innovative fluid and power systems. As a Process Engineer, you'll drive the development and optimization of cutting-edge technologies in a f...
1 week ago
$135K - $165K *
Pioneer operational excellence in Design leadership, managing workflows, prioritizing projects, and developing talent. Collaborate cross-functionally to enhance Design integration in AI-driven product...
1 week ago
Director, Health Plans (Account Executive)
$120K - $135K *
Support the growth of health plan accounts by fostering client relationships, analyzing data, and driving retention in a fast-paced, independent role. Leverage strong communication and analytical skil...
4 weeks ago
Senior Manager - APR DRG Concept Development Analyst
$100K - $125K *
Transform healthcare analytics by leading the development of APR-DRG audit criteria. Collaborate with cross-functional teams to enhance payment integrity through data-driven insights and innovative so...
1 week ago
Vice President, Business Intelligence Engineer
$150K - $180K *
Innovate data-driven strategies to enhance business decision-making and optimize reporting processes. Leverage expertise in BI, CRM Analytics, and Salesforce to deliver actionable insights and support...
Reposted yesterday
Regional Sales Director - Memphis
$180K - $215K *
Lead the charge in regional sales execution, driving product launch success and team performance through strategic planning, customer engagement, and cross-functional collaboration in a dynamic enviro...
1 week ago
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.